BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 35863436)

  • 1. The amino acid sensor GCN2 suppresses terminal oligopyrimidine (TOP) mRNA translation via La-related protein 1 (LARP1).
    Farooq Z; Kusuma F; Burke P; Dufour CR; Lee D; Tabatabaei N; Toboz P; Radovani E; Greenblatt JF; Rehman J; Class J; Khoutorsky A; Fonseca BD; Richner JM; Mercier E; Bourque G; Giguère V; Subramaniam AR; Han J; Tahmasebi S
    J Biol Chem; 2022 Sep; 298(9):102277. PubMed ID: 35863436
    [TBL] [Abstract][Full Text] [Related]  

  • 2. La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1).
    Fonseca BD; Zakaria C; Jia JJ; Graber TE; Svitkin Y; Tahmasebi S; Healy D; Hoang HD; Jensen JM; Diao IT; Lussier A; Dajadian C; Padmanabhan N; Wang W; Matta-Camacho E; Hearnden J; Smith EM; Tsukumo Y; Yanagiya A; Morita M; Petroulakis E; González JL; Hernández G; Alain T; Damgaard CK
    J Biol Chem; 2015 Jun; 290(26):15996-6020. PubMed ID: 25940091
    [TBL] [Abstract][Full Text] [Related]  

  • 3. La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs.
    Lahr RM; Fonseca BD; Ciotti GE; Al-Ashtal HA; Jia JJ; Niklaus MR; Blagden SP; Alain T; Berman AJ
    Elife; 2017 Apr; 6():. PubMed ID: 28379136
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Distinct roles of LARP1 and 4EBP1/2 in regulating translation and stability of 5'TOP mRNAs.
    Hochstoeger T; Papasaikas P; Piskadlo E; Chao JA
    Sci Adv; 2024 Feb; 10(7):eadi7830. PubMed ID: 38363833
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation.
    Tcherkezian J; Cargnello M; Romeo Y; Huttlin EL; Lavoie G; Gygi SP; Roux PP
    Genes Dev; 2014 Feb; 28(4):357-71. PubMed ID: 24532714
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Translational coregulation of 5'TOP mRNAs by TIA-1 and TIAR.
    Damgaard CK; Lykke-Andersen J
    Genes Dev; 2011 Oct; 25(19):2057-68. PubMed ID: 21979918
    [TBL] [Abstract][Full Text] [Related]  

  • 7. La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region.
    Philippe L; Vasseur JJ; Debart F; Thoreen CC
    Nucleic Acids Res; 2018 Feb; 46(3):1457-1469. PubMed ID: 29244122
    [TBL] [Abstract][Full Text] [Related]  

  • 8. LARP1 on TOP of ribosome production.
    Fonseca BD; Lahr RM; Damgaard CK; Alain T; Berman AJ
    Wiley Interdiscip Rev RNA; 2018 Sep; 9(5):e1480. PubMed ID: 29722158
    [TBL] [Abstract][Full Text] [Related]  

  • 9. mTORC1 promotes TOP mRNA translation through site-specific phosphorylation of LARP1.
    Jia JJ; Lahr RM; Solgaard MT; Moraes BJ; Pointet R; Yang AD; Celucci G; Graber TE; Hoang HD; Niklaus MR; Pena IA; Hollensen AK; Smith EM; Chaker-Margot M; Anton L; Dajadian C; Livingstone M; Hearnden J; Wang XD; Yu Y; Maier T; Damgaard CK; Berman AJ; Alain T; Fonseca BD
    Nucleic Acids Res; 2021 Apr; 49(6):3461-3489. PubMed ID: 33398329
    [TBL] [Abstract][Full Text] [Related]  

  • 10. LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs.
    Hong S; Freeberg MA; Han T; Kamath A; Yao Y; Fukuda T; Suzuki T; Kim JK; Inoki K
    Elife; 2017 Jun; 6():. PubMed ID: 28650797
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GCN2- and eIF2α-phosphorylation-independent, but ATF4-dependent, induction of CARE-containing genes in methionine-deficient cells.
    Mazor KM; Stipanuk MH
    Amino Acids; 2016 Dec; 48(12):2831-2842. PubMed ID: 27613409
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A unifying model for mTORC1-mediated regulation of mRNA translation.
    Thoreen CC; Chantranupong L; Keys HR; Wang T; Gray NS; Sabatini DM
    Nature; 2012 May; 485(7396):109-13. PubMed ID: 22552098
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.
    Guan BJ; Krokowski D; Majumder M; Schmotzer CL; Kimball SR; Merrick WC; Koromilas AE; Hatzoglou M
    J Biol Chem; 2014 May; 289(18):12593-611. PubMed ID: 24648524
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells.
    Kim Y; Sundrud MS; Zhou C; Edenius M; Zocco D; Powers K; Zhang M; Mazitschek R; Rao A; Yeo CY; Noss EH; Brenner MB; Whitman M; Keller TL
    Proc Natl Acad Sci U S A; 2020 Apr; 117(16):8900-8911. PubMed ID: 32253314
    [TBL] [Abstract][Full Text] [Related]  

  • 15. mTOR- and LARP1-dependent regulation of TOP mRNA poly(A) tail and ribosome loading.
    Ogami K; Oishi Y; Sakamoto K; Okumura M; Yamagishi R; Inoue T; Hibino M; Nogimori T; Yamaguchi N; Furutachi K; Hosoda N; Inagaki H; Hoshino SI
    Cell Rep; 2022 Oct; 41(4):111548. PubMed ID: 36288708
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice.
    Yamazaki H; Kasai S; Mimura J; Ye P; Inose-Maruyama A; Tanji K; Wakabayashi K; Mizuno S; Sugiyama F; Takahashi S; Sato T; Ozaki T; Cavener DR; Yamamoto M; Itoh K
    PLoS Genet; 2020 Apr; 16(4):e1008693. PubMed ID: 32324833
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Autogenous Control of 5′TOP mRNA Stability by 40S Ribosomes.
    Gentilella A; Morón-Duran FD; Fuentes P; Zweig-Rocha G; Riaño-Canalias F; Pelletier J; Ruiz M; Turón G; Castaño J; Tauler A; Bueno C; Menéndez P; Kozma SC; Thomas G
    Mol Cell; 2017 Jul; 67(1):55-70.e4. PubMed ID: 28673543
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Time-resolved analysis of amino acid stress identifies eIF2 phosphorylation as necessary to inhibit mTORC1 activity in liver.
    Nikonorova IA; Mirek ET; Signore CC; Goudie MP; Wek RC; Anthony TG
    J Biol Chem; 2018 Apr; 293(14):5005-5015. PubMed ID: 29449374
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of activating transcription factor 4 in the hepatic response to amino acid depletion by asparaginase.
    Al-Baghdadi RJT; Nikonorova IA; Mirek ET; Wang Y; Park J; Belden WJ; Wek RC; Anthony TG
    Sci Rep; 2017 Apr; 7(1):1272. PubMed ID: 28455513
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An unusual mode of baseline translation adjusts cellular protein synthesis capacity to metabolic needs.
    Schneider C; Erhard F; Binotti B; Buchberger A; Vogel J; Fischer U
    Cell Rep; 2022 Oct; 41(2):111467. PubMed ID: 36223745
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.