260 related articles for article (PubMed ID: 35886887)
1. Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity.
Darwish S; Ghazy E; Heimburg T; Herp D; Zeyen P; Salem-Altintas R; Ridinger J; Robaa D; Schmidtkunz K; Erdmann F; Schmidt M; Romier C; Jung M; Oehme I; Sippl W
Int J Mol Sci; 2022 Jul; 23(14):. PubMed ID: 35886887
[TBL] [Abstract][Full Text] [Related]
2. Structure-Based Design and Biological Characterization of Selective Histone Deacetylase 8 (HDAC8) Inhibitors with Anti-Neuroblastoma Activity.
Heimburg T; Kolbinger FR; Zeyen P; Ghazy E; Herp D; Schmidtkunz K; Melesina J; Shaik TB; Erdmann F; Schmidt M; Romier C; Robaa D; Witt O; Oehme I; Jung M; Sippl W
J Med Chem; 2017 Dec; 60(24):10188-10204. PubMed ID: 29190092
[TBL] [Abstract][Full Text] [Related]
3. Discovery of highly potent HDAC8 PROTACs with anti-tumor activity.
Zhao C; Chen D; Suo F; Setroikromo R; Quax WJ; Dekker FJ
Bioorg Chem; 2023 Jul; 136():106546. PubMed ID: 37098288
[TBL] [Abstract][Full Text] [Related]
4. Selective degradation of histone deacetylase 8 mediated by a proteolysis targeting chimera (PROTAC).
Chotitumnavee J; Yamashita Y; Takahashi Y; Takada Y; Iida T; Oba M; Itoh Y; Suzuki T
Chem Commun (Camb); 2022 Apr; 58(29):4635-4638. PubMed ID: 35311871
[TBL] [Abstract][Full Text] [Related]
5. Discovery of pomalidomide-based PROTACs for selective degradation of histone deacetylase 8.
Sun Z; Deng B; Yang Z; Mai R; Huang J; Ma Z; Chen T; Chen J
Eur J Med Chem; 2022 Sep; 239():114544. PubMed ID: 35759908
[TBL] [Abstract][Full Text] [Related]
6. A Therapeutic Perspective of HDAC8 in Different Diseases: An Overview of Selective Inhibitors.
Fontana A; Cursaro I; Carullo G; Gemma S; Butini S; Campiani G
Int J Mol Sci; 2022 Sep; 23(17):. PubMed ID: 36077415
[TBL] [Abstract][Full Text] [Related]
7. Design of Potent Panobinostat Histone Deacetylase Inhibitor Derivatives: Molecular Considerations for Enhanced Isozyme Selectivity between HDAC2 and HDAC8.
Stoddard SV; May XA; Rivas F; Dodson K; Vijayan S; Adhika S; Parker K; Watkins DL
Mol Inform; 2019 Mar; 38(3):e1800080. PubMed ID: 30369061
[TBL] [Abstract][Full Text] [Related]
8. Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation.
Rettig I; Koeneke E; Trippel F; Mueller WC; Burhenne J; Kopp-Schneider A; Fabian J; Schober A; Fernekorn U; von Deimling A; Deubzer HE; Milde T; Witt O; Oehme I
Cell Death Dis; 2015 Feb; 6(2):e1657. PubMed ID: 25695609
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis, and biological activity of NCC149 derivatives as histone deacetylase 8-selective inhibitors.
Suzuki T; Muto N; Bando M; Itoh Y; Masaki A; Ri M; Ota Y; Nakagawa H; Iida S; Shirahige K; Miyata N
ChemMedChem; 2014 Mar; 9(3):657-64. PubMed ID: 24403121
[TBL] [Abstract][Full Text] [Related]
10. Structure-Based Discovery of Selective Histone Deacetylase 8 Degraders with Potent Anticancer Activity.
Huang J; Zhang J; Xu W; Wu Q; Zeng R; Liu Z; Tao W; Chen Q; Wang Y; Zhu WG
J Med Chem; 2023 Jan; 66(2):1186-1209. PubMed ID: 36516047
[TBL] [Abstract][Full Text] [Related]
11. Discovery of meta-sulfamoyl N-hydroxybenzamides as HDAC8 selective inhibitors.
Zhao C; Zang J; Ding Q; Inks ES; Xu W; Chou CJ; Zhang Y
Eur J Med Chem; 2018 Apr; 150():282-291. PubMed ID: 29533873
[TBL] [Abstract][Full Text] [Related]
12. Histone deacetylase 8 in neuroblastoma tumorigenesis.
Oehme I; Deubzer HE; Wegener D; Pickert D; Linke JP; Hero B; Kopp-Schneider A; Westermann F; Ulrich SM; von Deimling A; Fischer M; Witt O
Clin Cancer Res; 2009 Jan; 15(1):91-9. PubMed ID: 19118036
[TBL] [Abstract][Full Text] [Related]
13. Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants.
Marek M; Shaik TB; Heimburg T; Chakrabarti A; Lancelot J; Ramos-Morales E; Da Veiga C; Kalinin D; Melesina J; Robaa D; Schmidtkunz K; Suzuki T; Holl R; Ennifar E; Pierce RJ; Jung M; Sippl W; Romier C
J Med Chem; 2018 Nov; 61(22):10000-10016. PubMed ID: 30347148
[TBL] [Abstract][Full Text] [Related]
14. Discovery of novel potential selective HDAC8 inhibitors by combine ligand-based, structure-based virtual screening and in-vitro biological evaluation.
Debnath S; Debnath T; Bhaumik S; Majumdar S; Kalle AM; Aparna V
Sci Rep; 2019 Nov; 9(1):17174. PubMed ID: 31748509
[TBL] [Abstract][Full Text] [Related]
15. Methionine 274 Is Not the Determining Factor for Selective Inhibition of Histone Deacetylase 8 (HDAC8) by L-Shaped Inhibitors.
Jänsch N; Lang KL; Meyer-Almes FJ
Int J Mol Sci; 2022 Oct; 23(19):. PubMed ID: 36233076
[TBL] [Abstract][Full Text] [Related]
16. Characterization of Conformationally Constrained Benzanilide Scaffolds for Potent and Selective HDAC8 Targeting.
Hassan MM; Israelian J; Nawar N; Ganda G; Manaswiyoungkul P; Raouf YS; Armstrong D; Sedighi A; Olaoye OO; Erdogan F; Cabral AD; Angeles F; Altintas R; de Araujo ED; Gunning PT
J Med Chem; 2020 Aug; 63(15):8634-8648. PubMed ID: 32672458
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and Investigation of Therapeutic Potential of Isoform-Specific HDAC8 Inhibitors for the Treatment of Cutaneous T Cell Lymphoma.
Umamaheswari A; Puratchikody A; Hari N
Anticancer Agents Med Chem; 2019; 19(7):916-934. PubMed ID: 30836926
[TBL] [Abstract][Full Text] [Related]
18. Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressor.
Hu E; Chen Z; Fredrickson T; Zhu Y; Kirkpatrick R; Zhang GF; Johanson K; Sung CM; Liu R; Winkler J
J Biol Chem; 2000 May; 275(20):15254-64. PubMed ID: 10748112
[TBL] [Abstract][Full Text] [Related]
19. Advances in the Design and Development of PROTAC-mediated HDAC Degradation.
Rodrigues DA; Roe A; Griffith D; Chonghaile TN
Curr Top Med Chem; 2022 Mar; 22(5):408-424. PubMed ID: 34649488
[TBL] [Abstract][Full Text] [Related]
20. Discovery of histone deacetylase 3 (HDAC3)-specific PROTACs.
Xiao Y; Wang J; Zhao LY; Chen X; Zheng G; Zhang X; Liao D
Chem Commun (Camb); 2020 Aug; 56(68):9866-9869. PubMed ID: 32840532
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
