BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 35889210)

  • 1. A Novel ERK2 Degrader Z734 Induces Apoptosis of MCF-7 Cells via the HERC3/p53 Signaling Pathway.
    Xu S; Xiong Y; Yao R; Tian R; Meng Z; Zaky MY; Fu B; Guo D; Wang L; Lin F; Lin X; Wu H
    Molecules; 2022 Jul; 27(14):. PubMed ID: 35889210
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity.
    Menendez JA; Vellon L; Colomer R; Lupu R
    Int J Cancer; 2005 May; 115(1):19-35. PubMed ID: 15657900
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HERC3 regulates epithelial-mesenchymal transition by directly ubiquitination degradation EIF5A2 and inhibits metastasis of colorectal cancer.
    Zhang Z; He G; Lv Y; Liu Y; Niu Z; Feng Q; Hu R; Xu J
    Cell Death Dis; 2022 Jan; 13(1):74. PubMed ID: 35064108
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A network of substrates of the E3 ubiquitin ligases MDM2 and HUWE1 control apoptosis independently of p53.
    Kurokawa M; Kim J; Geradts J; Matsuura K; Liu L; Ran X; Xia W; Ribar TJ; Henao R; Dewhirst MW; Kim WJ; Lucas JE; Wang S; Spector NL; Kornbluth S
    Sci Signal; 2013 May; 6(274):ra32. PubMed ID: 23652204
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Repositioning of amprenavir as a novel extracellular signal-regulated kinase-2 inhibitor and apoptosis inducer in MCF-7 human breast cancer.
    Jiang W; Li X; Li T; Wang H; Shi W; Qi P; Li C; Chen J; Bao J; Huang G; Wang Y
    Int J Oncol; 2017 Mar; 50(3):823-834. PubMed ID: 28197631
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel CYR61-triggered 'CYR61-alphavbeta3 integrin loop' regulates breast cancer cell survival and chemosensitivity through activation of ERK1/ERK2 MAPK signaling pathway.
    Menendez JA; Vellon L; Mehmi I; Teng PK; Griggs DW; Lupu R
    Oncogene; 2005 Jan; 24(5):761-79. PubMed ID: 15592521
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA; Mehmi I; Atlas E; Colomer R; Lupu R
    Int J Oncol; 2004 Mar; 24(3):591-608. PubMed ID: 14767544
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HERC3 directly targets RPL23A for ubiquitination degradation and further regulates Colorectal Cancer proliferation and the cell cycle.
    Zhang Z; Wu Q; Fang M; Liu Y; Jiang J; Feng Q; Hu R; Xu J
    Int J Biol Sci; 2022; 18(8):3282-3297. PubMed ID: 35637966
    [No Abstract]   [Full Text] [Related]  

  • 9. Targeting UBR5 inhibits postsurgical breast cancer lung metastases by inducing CDC73 and p53 mediated apoptosis.
    Yu Z; Dong X; Song M; Xu A; He Q; Li H; Ouyang W; Chouchane L; Ma X
    Int J Cancer; 2024 Feb; 154(4):723-737. PubMed ID: 37855385
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CK2-mediated CCDC106 phosphorylation is required for p53 degradation in cancer progression.
    Ning Y; Wang C; Liu X; Du Y; Liu S; Liu K; Zhou J; Zhou C
    J Exp Clin Cancer Res; 2019 Mar; 38(1):131. PubMed ID: 30885251
    [TBL] [Abstract][Full Text] [Related]  

  • 11. BCAS3 exhibits oncogenic properties by promoting CRL4A-mediated ubiquitination of p53 in breast cancer.
    Zhou Z; Qiu R; Liu W; Yang T; Li G; Huang W; Teng X; Yang Y; Yu H; Yang Y; Wang Y
    Cell Prolif; 2021 Aug; 54(8):e13088. PubMed ID: 34240781
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SCO2 induces p53-mediated apoptosis by Thr845 phosphorylation of ASK-1 and dissociation of the ASK-1-Trx complex.
    Madan E; Gogna R; Kuppusamy P; Bhatt M; Mahdi AA; Pati U
    Mol Cell Biol; 2013 Apr; 33(7):1285-302. PubMed ID: 23319048
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HOTAIR may regulate proliferation, apoptosis, migration and invasion of MCF-7 cells through regulating the P53/Akt/JNK signaling pathway.
    Yu Y; Lv F; Liang D; Yang Q; Zhang B; Lin H; Wang X; Qian G; Xu J; You W
    Biomed Pharmacother; 2017 Jun; 90():555-561. PubMed ID: 28407576
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modulation of cyclins, p53 and mitogen-activated protein kinases signaling in breast cancer cell lines by 4-(3,4,5-trimethoxyphenoxy)benzoic acid.
    Lee KH; Ho WY; Wu SJ; Omar HA; Huang PJ; Wang CC; Hung JH
    Int J Mol Sci; 2014 Jan; 15(1):743-57. PubMed ID: 24406729
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tumor suppressor OTUD3 induces growth inhibition and apoptosis by directly deubiquitinating and stabilizing p53 in invasive breast carcinoma cells.
    Pu Q; Lv YR; Dong K; Geng WW; Gao HD
    BMC Cancer; 2020 Jun; 20(1):583. PubMed ID: 32571254
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The ubiquitin ligase COP1 regulates cell cycle and apoptosis by affecting p53 function in human breast cancer cell lines.
    Ka WH; Cho SK; Chun BN; Byun SY; Ahn JC
    Breast Cancer; 2018 Sep; 25(5):529-538. PubMed ID: 29516369
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Penta-O-galloyl-beta-D-glucose induces G1 arrest and DNA replicative S-phase arrest independently of cyclin-dependent kinase inhibitor 1A, cyclin-dependent kinase inhibitor 1B and P53 in human breast cancer cells and is orally active against triple negative xenograft growth.
    Chai Y; Lee HJ; Shaik AA; Nkhata K; Xing C; Zhang J; Jeong SJ; Kim SH; Lu J
    Breast Cancer Res; 2010; 12(5):R67. PubMed ID: 20809980
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol inhibits MDM2 and induces apoptosis in breast cancer cells through a p53-independent pathway.
    Xu J; Han M; Shen J; Guan Q; Bai Z; Lang B; Zhang H; Li Z; Zuo D; Zhang W; Wu Y
    Cancer Lett; 2016 Dec; 383(1):9-17. PubMed ID: 27693458
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Plumbagin from a tropical pitcher plant (Nepenthes alata Blanco) induces apoptotic cell death via a p53-dependent pathway in MCF-7 human breast cancer cells.
    De U; Son JY; Jeon Y; Ha SY; Park YJ; Yoon S; Ha KT; Choi WS; Lee BM; Kim IS; Kwak JH; Kim HS
    Food Chem Toxicol; 2019 Jan; 123():492-500. PubMed ID: 30458268
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p53 can inhibit cell proliferation through caspase-mediated cleavage of ERK2/MAPK.
    Marchetti A; Cecchinelli B; D'Angelo M; D'Orazi G; Crescenzi M; Sacchi A; Soddu S
    Cell Death Differ; 2004 Jun; 11(6):596-607. PubMed ID: 15150542
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.