BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

324 related articles for article (PubMed ID: 35891385)

  • 1. Inhibitors of Deubiquitinating Enzymes Interfere with the SARS-CoV-2 Papain-like Protease and Block Virus Replication In Vitro.
    Große M; Setz C; Rauch P; Auth J; Morokutti-Kurz M; Temchura V; Schubert U
    Viruses; 2022 Jun; 14(7):. PubMed ID: 35891385
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivo.
    van Huizen M; Bloeme-Ter Horst JR; de Gruyter HLM; Geurink PP; van der Heden van Noort GJ; Knaap RCM; Nelemans T; Ogando NS; Leijs AA; Urakova N; Mark BL; Snijder EJ; Myeni SK; Kikkert M
    PLoS Pathog; 2024 Mar; 20(3):e1012100. PubMed ID: 38527094
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity.
    Barretto N; Jukneliene D; Ratia K; Chen Z; Mesecar AD; Baker SC
    J Virol; 2005 Dec; 79(24):15189-98. PubMed ID: 16306590
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The papain-like protease from the severe acute respiratory syndrome coronavirus is a deubiquitinating enzyme.
    Lindner HA; Fotouhi-Ardakani N; Lytvyn V; Lachance P; Sulea T; Ménard R
    J Virol; 2005 Dec; 79(24):15199-208. PubMed ID: 16306591
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Coronaviral PLpro proteases and the immunomodulatory roles of conjugated versus free Interferon Stimulated Gene product-15 (ISG15).
    Gold IM; Reis N; Glaser F; Glickman MH
    Semin Cell Dev Biol; 2022 Dec; 132():16-26. PubMed ID: 35764457
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nidovirus papain-like proteases: multifunctional enzymes with protease, deubiquitinating and deISGylating activities.
    Mielech AM; Chen Y; Mesecar AD; Baker SC
    Virus Res; 2014 Dec; 194():184-90. PubMed ID: 24512893
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Catalytic function and substrate specificity of the papain-like protease domain of nsp3 from the Middle East respiratory syndrome coronavirus.
    Báez-Santos YM; Mielech AM; Deng X; Baker S; Mesecar AD
    J Virol; 2014 Nov; 88(21):12511-27. PubMed ID: 25142582
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site.
    van Vliet VJE; Huynh N; Palà J; Patel A; Singer A; Slater C; Chung J; van Huizen M; Teyra J; Miersch S; Luu GK; Ye W; Sharma N; Ganaie SS; Russell R; Chen C; Maynard M; Amarasinghe GK; Mark BL; Kikkert M; Sidhu SS
    PLoS Pathog; 2022 Dec; 18(12):e1011065. PubMed ID: 36548304
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors.
    Osipiuk J; Azizi SA; Dvorkin S; Endres M; Jedrzejczak R; Jones KA; Kang S; Kathayat RS; Kim Y; Lisnyak VG; Maki SL; Nicolaescu V; Taylor CA; Tesar C; Zhang YA; Zhou Z; Randall G; Michalska K; Snyder SA; Dickinson BC; Joachimiak A
    Nat Commun; 2021 Feb; 12(1):743. PubMed ID: 33531496
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity.
    Shin D; Mukherjee R; Grewe D; Bojkova D; Baek K; Bhattacharya A; Schulz L; Widera M; Mehdipour AR; Tascher G; Geurink PP; Wilhelm A; van der Heden van Noort GJ; Ovaa H; Müller S; Knobeloch KP; Rajalingam K; Schulman BA; Cinatl J; Hummer G; Ciesek S; Dikic I
    Nature; 2020 Nov; 587(7835):657-662. PubMed ID: 32726803
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of the Ubiquitin and ISG15 Deconjugase Activity of SARS-CoV-1 and SARS-CoV-2 Papain-Like Protease.
    Nayak D; Dos Santos Bury P; Drag M; Nijkerk AN; El Oualid F; Olsen SK
    Methods Mol Biol; 2023; 2591():171-188. PubMed ID: 36350549
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Preparation and characterization of nanobodies targeting SARS-CoV-2 papain-like protease.
    Qiao H; Li L; Wang L; Yu H; Hu F; Zhou X; Yang H; Xu J; Meng X; Geng Y; Dai Y
    Protein Expr Purif; 2023 Jul; 207():106267. PubMed ID: 37030644
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization and Noncovalent Inhibition of the Deubiquitinase and deISGylase Activity of SARS-CoV-2 Papain-Like Protease.
    Freitas BT; Durie IA; Murray J; Longo JE; Miller HC; Crich D; Hogan RJ; Tripp RA; Pegan SD
    ACS Infect Dis; 2020 Aug; 6(8):2099-2109. PubMed ID: 32428392
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease.
    Patchett S; Lv Z; Rut W; Békés M; Drag M; Olsen SK; Huang TT
    Cell Rep; 2021 Sep; 36(13):109754. PubMed ID: 34547223
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Binding of SARS-CoV Covalent Non-Covalent Inhibitors to the SARS-CoV-2 Papain-Like Protease and Ovarian Tumor Domain Deubiquitinases.
    Sivakumar D; Stein M
    Biomolecules; 2021 May; 11(6):. PubMed ID: 34071582
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Losartan Inhibits SARS-CoV-2 Replication in Vitro.
    Nejat R; Sadr AS; Freitas B; Crabttree J; Pegan SD; Tripp RA; Najafi D
    J Pharm Pharm Sci; 2021; 24():390-399. PubMed ID: 34319871
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chalcone-amide, a privileged backbone for the design and development of selective SARS-CoV/SARS-CoV-2 papain-like protease inhibitors.
    Valipour M
    Eur J Med Chem; 2022 Oct; 240():114572. PubMed ID: 35797899
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Parthenolide reveals an allosteric mode to inhibit the deISGylation activity of SARS-CoV‑2 papain-like protease.
    Zou Z; Shan H; Sun D; Xia L; Shi Y; Wan J; Zhou A; Wu Y; Xu H; Lei H; Xu Z; Wu Y
    Acta Biochim Biophys Sin (Shanghai); 2022 Aug; 54(8):1133-1139. PubMed ID: 35866602
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting papain-like protease by natural products as novel therapeutic potential SARS-CoV-2.
    Waqas M; Ullah S; Halim SA; Rehman NU; Ali A; Jan A; Muhsinah AB; Khan A; Al-Harrasi A
    Int J Biol Macromol; 2024 Feb; 258(Pt 1):128812. PubMed ID: 38114011
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses.
    Deng X; Agnihothram S; Mielech AM; Nichols DB; Wilson MW; StJohn SE; Larsen SD; Mesecar AD; Lenschow DJ; Baric RS; Baker SC
    J Virol; 2014 Oct; 88(20):11825-33. PubMed ID: 25100850
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.