These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 35891446)

  • 21. Structure of a HIV-1 IN-Allosteric inhibitor complex at 2.93 Å resolution: Routes to inhibitor optimization.
    Eilers G; Gupta K; Allen A; Montermoso S; Murali H; Sharp R; Hwang Y; Bushman FD; Van Duyne G
    PLoS Pathog; 2023 Mar; 19(3):e1011097. PubMed ID: 36867659
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function.
    Singer MR; Dinh T; Levintov L; Annamalai AS; Rey JS; Briganti L; Cook NJ; Pye VE; Taylor IA; Kim K; Engelman AN; Kim B; Perilla JR; Kvaratskhelia M; Cherepanov P
    mBio; 2023 Feb; 14(1):e0356022. PubMed ID: 36744954
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Design, synthesis and SAR study of novel C2-pyrazolopyrimidine amides and amide isosteres as allosteric integrase inhibitors.
    Patel M; Cianci C; Allard CW; Parker DD; Simmermacher J; Jenkins S; Mcauliffe B; Minassian B; Discotto L; Krystal M; Meanwell NA; Naidu BN
    Bioorg Med Chem Lett; 2020 Nov; 30(21):127516. PubMed ID: 32860982
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Design, Synthesis, and Preclinical Profiling of GSK3739936 (BMS-986180), an Allosteric Inhibitor of HIV-1 Integrase with Broad-Spectrum Activity toward 124/125 Polymorphs.
    Naidu BN; Patel M; McAuliffe B; Ding B; Cianci C; Simmermacher J; Jenkins S; Parker DD; Sivaprakasam P; Khan JA; Kish K; Lewis H; Hanumegowda U; Krystal M; Meanwell NA; Kadow JF
    J Med Chem; 2022 Mar; 65(6):4949-4971. PubMed ID: 35235334
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Allosteric inhibition of HIV-1 integrase activity.
    Engelman A; Kessl JJ; Kvaratskhelia M
    Curr Opin Chem Biol; 2013 Jun; 17(3):339-45. PubMed ID: 23647983
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Allosteric HIV Integrase Inhibitors Promote Formation of Inactive Branched Polymers via Homomeric Carboxy-Terminal Domain Interactions.
    Gupta K; Allen A; Giraldo C; Eilers G; Sharp R; Hwang Y; Murali H; Cruz K; Janmey P; Bushman F; Van Duyne GD
    Structure; 2021 Mar; 29(3):213-225.e5. PubMed ID: 33357410
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase.
    Bonnard D; Le Rouzic E; Singer MR; Yu Z; Le Strat F; Batisse C; Batisse J; Amadori C; Chasset S; Pye VE; Emiliani S; Ledoussal B; Ruff M; Moreau F; Cherepanov P; Benarous R
    Antimicrob Agents Chemother; 2023 Jul; 67(7):e0046223. PubMed ID: 37310224
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Multimodal mechanism of action of allosteric HIV-1 integrase inhibitors.
    Jurado KA; Engelman A
    Expert Rev Mol Med; 2013 Nov; 15():e14. PubMed ID: 24274067
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Quinoline-based Protein-protein Interaction Inhibitors of LEDGF/p75 and HIV Integrase: An In Silico Study.
    Chhokar N; Kalra S; Chauhan M; Munshi A; Kumar R
    Curr Top Med Chem; 2018; 18(32):2800-2815. PubMed ID: 30747071
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Antiviral Activity and Resistance Profile of the Novel HIV-1 Non-Catalytic Site Integrase Inhibitor JTP-0157602.
    Ohata Y; Tomonaga M; Watanabe Y; Tomura K; Kimura K; Akaki T; Adachi K; Kodama EN; Matsuzaki Y; Hayashi H
    J Virol; 2022 Mar; 96(6):e0184321. PubMed ID: 35045265
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Distribution and Redistribution of HIV-1 Nucleocapsid Protein in Immature, Mature, and Integrase-Inhibited Virions: a Role for Integrase in Maturation.
    Fontana J; Jurado KA; Cheng N; Ly NL; Fuchs JR; Gorelick RJ; Engelman AN; Steven AC
    J Virol; 2015 Oct; 89(19):9765-80. PubMed ID: 26178982
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Crystal structure of the HIV-1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site.
    Wielens J; Headey SJ; Jeevarajah D; Rhodes DI; Deadman J; Chalmers DK; Scanlon MJ; Parker MW
    FEBS Lett; 2010 Apr; 584(8):1455-62. PubMed ID: 20227411
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site.
    Maehigashi T; Ahn S; Kim UI; Lindenberger J; Oo A; Koneru PC; Mahboubi B; Engelman AN; Kvaratskhelia M; Kim K; Kim B
    PLoS Pathog; 2021 Jul; 17(7):e1009671. PubMed ID: 34293041
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Resistance to pyridine-based inhibitor KF116 reveals an unexpected role of integrase in HIV-1 Gag-Pol polyprotein proteolytic processing.
    Hoyte AC; Jamin AV; Koneru PC; Kobe MJ; Larue RC; Fuchs JR; Engelman AN; Kvaratskhelia M
    J Biol Chem; 2017 Dec; 292(48):19814-19825. PubMed ID: 28972144
    [TBL] [Abstract][Full Text] [Related]  

  • 35. A Conformational Escape Reaction of HIV-1 against an Allosteric Integrase Inhibitor.
    Nakamura T; Nakamura T; Amano M; Miyakawa T; Yamagata Y; Matsuoka M; Nakata H
    J Virol; 2020 Sep; 94(19):. PubMed ID: 32611758
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Structure-function analyses unravel distinct effects of allosteric inhibitors of HIV-1 integrase on viral maturation and integration.
    Bonnard D; Le Rouzic E; Eiler S; Amadori C; Orlov I; Bruneau JM; Brias J; Barbion J; Chevreuil F; Spehner D; Chasset S; Ledoussal B; Moreau F; Saïb A; Klaholz BP; Emiliani S; Ruff M; Zamborlini A; Benarous R
    J Biol Chem; 2018 Apr; 293(16):6172-6186. PubMed ID: 29507092
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Kuwanon-L as a New Allosteric HIV-1 Integrase Inhibitor: Molecular Modeling and Biological Evaluation.
    Esposito F; Tintori C; Martini R; Christ F; Debyser Z; Ferrarese R; Cabiddu G; Corona A; Ceresola ER; Calcaterra A; Iovine V; Botta B; Clementi M; Canducci F; Botta M; Tramontano E
    Chembiochem; 2015 Nov; 16(17):2507-12. PubMed ID: 26360521
    [TBL] [Abstract][Full Text] [Related]  

  • 38. New class of HIV-1 integrase (IN) inhibitors with a dual mode of action.
    Tsiang M; Jones GS; Niedziela-Majka A; Kan E; Lansdon EB; Huang W; Hung M; Samuel D; Novikov N; Xu Y; Mitchell M; Guo H; Babaoglu K; Liu X; Geleziunas R; Sakowicz R
    J Biol Chem; 2012 Jun; 287(25):21189-203. PubMed ID: 22535962
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Methods for the Analyses of Inhibitor-Induced Aberrant Multimerization of HIV-1 Integrase.
    Kessl JJ; Sharma A; Kvaratskhelia M
    Methods Mol Biol; 2016; 1354():149-64. PubMed ID: 26714710
    [TBL] [Abstract][Full Text] [Related]  

  • 40. 3D-QSAR studies of quinoline ring derivatives as HIV-1 integrase inhibitors.
    Sun XH; Guan JQ; Tan JJ; Liu C; Wang CX
    SAR QSAR Environ Res; 2012 Oct; 23(7-8):683-703. PubMed ID: 22991976
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.