154 related articles for article (PubMed ID: 35892288)
1. A Coumarin-Donepezil Hybrid as a Blood-Brain Barrier Permeable Dual Cholinesterase Inhibitor: Isolation, Synthetic Modifications, and Biological Evaluation of Natural Coumarins.
Sharma A; Nuthakki VK; Gairola S; Singh B; Bharate SB
ChemMedChem; 2022 Sep; 17(18):e202200300. PubMed ID: 35892288
[TBL] [Abstract][Full Text] [Related]
2. Identification of aplysinopsin as a blood-brain barrier permeable scaffold for anti-cholinesterase and anti-BACE-1 activity.
Nuthakki VK; Yadav Bheemanaboina RR; Bharate SB
Bioorg Chem; 2021 Feb; 107():104568. PubMed ID: 33418314
[TBL] [Abstract][Full Text] [Related]
3. New coumarin-benzotriazole based hybrid molecules as inhibitors of acetylcholinesterase and amyloid aggregation.
Singh A; Sharma S; Arora S; Attri S; Kaur P; Kaur Gulati H; Bhagat K; Kumar N; Singh H; Vir Singh J; Mohinder Singh Bedi P
Bioorg Med Chem Lett; 2020 Oct; 30(20):127477. PubMed ID: 32781220
[TBL] [Abstract][Full Text] [Related]
4. Design, Synthesis, and Pharmacological Evaluation of Embelin-Aryl/alkyl Amine Hybrids as Orally Bioavailable Blood-Brain Barrier Permeable Multitargeted Agents with Therapeutic Potential in Alzheimer's Disease: Discovery of SB-1448.
Nuthakki VK; Choudhary S; Reddy CN; Bhatt S; Jamwal A; Jotshi A; Raghuvanshi R; Sharma A; Thakur S; Jadhav HR; Bharate SS; Nandi U; Kumar A; Bharate SB
ACS Chem Neurosci; 2023 Mar; 14(6):1193-1219. PubMed ID: 36812360
[TBL] [Abstract][Full Text] [Related]
5. Design and synthesis of donepezil analogues as dual AChE and BACE-1 inhibitors.
Gabr MT; Abdel-Raziq MS
Bioorg Chem; 2018 Oct; 80():245-252. PubMed ID: 29966870
[TBL] [Abstract][Full Text] [Related]
6. New phosphazine and phosphazide derivatives as multifunctional ligands targeting acetylcholinesterase and β-Amyloid aggregation for treatment of Alzheimer's disease.
El-Sayed NF; El-Hussieny M; Ewies EF; Fouad MA; Boulos LS
Bioorg Chem; 2020 Jan; 95():103499. PubMed ID: 31838287
[TBL] [Abstract][Full Text] [Related]
7. Multitargeted C9-substituted ester and ether derivatives of berberrubine for Alzheimer's disease: Design, synthesis, biological evaluation, metabolic stability, and pharmacokinetics.
Raghuvanshi R; Jamwal A; Nandi U; Bharate SB
Drug Dev Res; 2023 Feb; 84(1):121-140. PubMed ID: 36461610
[TBL] [Abstract][Full Text] [Related]
8. Blood-brain barrier permeable benzylpiperidin-4-yl-linked benzylamino benzamides as dual cholinesterase inhibitors.
Banoo R; Nuthakki VK; Abdullaha M; Sharma M; Bharate SB
Drug Dev Res; 2022 Dec; 83(8):1791-1802. PubMed ID: 36112736
[TBL] [Abstract][Full Text] [Related]
9. Development of coumarin-benzofuran hybrids as versatile multitargeted compounds for the treatment of Alzheimer's Disease.
Hiremathad A; Chand K; Keri RS
Chem Biol Drug Des; 2018 Aug; 92(2):1497-1503. PubMed ID: 29679445
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, and structure-activity relationship of caffeine-based triazoles as dual AChE and BACE-1 inhibitors.
Sharma M; Sharma A; Nuthakki VK; Bhatt S; Nandi U; Bharate SB
Drug Dev Res; 2022 Dec; 83(8):1803-1821. PubMed ID: 36161804
[TBL] [Abstract][Full Text] [Related]
11. Metformin and its sulphonamide derivative simultaneously potentiateanti-cholinesterase activity of donepezil and inhibit beta-amyloid aggregation.
Markowicz-Piasecka M; Huttunen KM; Sikora J
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):1309-1322. PubMed ID: 30251898
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and Biological Evaluation of Coumarin Triazoles as Dual Inhibitors of Cholinesterases and β-Secretase.
Sharma A; Bharate SB
ACS Omega; 2023 Mar; 8(12):11161-11176. PubMed ID: 37008108
[TBL] [Abstract][Full Text] [Related]
13. Syntheses of coumarin-tacrine hybrids as dual-site acetylcholinesterase inhibitors and their activity against butylcholinesterase, Aβ aggregation, and β-secretase.
Sun Q; Peng DY; Yang SG; Zhu XL; Yang WC; Yang GF
Bioorg Med Chem; 2014 Sep; 22(17):4784-91. PubMed ID: 25088549
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
Lan JS; Zhang T; Liu Y; Yang J; Xie SS; Liu J; Miao ZY; Ding Y
Eur J Med Chem; 2017 Jun; 133():184-196. PubMed ID: 28388521
[TBL] [Abstract][Full Text] [Related]
15. Combining Chalcones with Donepezil to Inhibit Both Cholinesterases and Aβ Fibril Assembly.
Thamban Chandrika N; Fosso MY; Tsodikov OV; LeVine Iii H; Garneau-Tsodikova S
Molecules; 2019 Dec; 25(1):. PubMed ID: 31878304
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis, and pharmacological evaluation of indole-piperidine amides as Blood-brain barrier permeable dual cholinesterase and β-secretase inhibitors.
Banoo R; Nuthakki VK; Wadje BN; Sharma A; Bharate SB
Eur J Med Chem; 2024 Feb; 266():116131. PubMed ID: 38215587
[TBL] [Abstract][Full Text] [Related]
17. Structure-based design, synthesis, and evaluation of structurally rigid donepezil analogues as dual AChE and BACE-1 inhibitors.
Gabr MT; Abdel-Raziq MS
Bioorg Med Chem Lett; 2018 Sep; 28(17):2910-2913. PubMed ID: 30017317
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis and biological evaluation of new coumarin-dithiocarbamate hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Jiang N; Huang Q; Liu J; Liang N; Li Q; Li Q; Xie SS
Eur J Med Chem; 2018 Feb; 146():287-298. PubMed ID: 29407958
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease.
Joubert J; Foka GB; Repsold BP; Oliver DW; Kapp E; Malan SF
Eur J Med Chem; 2017 Jan; 125():853-864. PubMed ID: 27744252
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis and evaluation of novel tacrine-coumarin hybrids as multifunctional cholinesterase inhibitors against Alzheimer's disease.
Xie SS; Wang XB; Li JY; Yang L; Kong LY
Eur J Med Chem; 2013 Jun; 64():540-53. PubMed ID: 23685572
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]