BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 35894141)

  • 1. Cryptotanshinone suppresses tumorigenesis by inhibiting lipogenesis and promoting reactive oxygen species production in KRAS‑activated pancreatic cancer cells.
    Terado T; Kim CJ; Ushio A; Minami K; Tambe Y; Kageyama S; Kawauchi A; Tsunoda T; Shirasawa S; Tanaka H; Inoue H
    Int J Oncol; 2022 Sep; 61(3):. PubMed ID: 35894141
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antitumor activity of potent pyruvate dehydrogenase kinase 4 inhibitors from plants in pancreatic cancer.
    Tambe Y; Terado T; Kim CJ; Mukaisho KI; Yoshida S; Sugihara H; Tanaka H; Chida J; Kido H; Yamaji K; Yamamoto T; Nakano H; Omura S; Inoue H
    Mol Carcinog; 2019 Oct; 58(10):1726-1737. PubMed ID: 31106493
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cryptotanshinone, a novel PDK 4 inhibitor, suppresses bladder cancer cell invasiveness via the mTOR/β‑catenin/N‑cadherin axis.
    Kim CJ; Terado T; Tambe Y; Mukaisho KI; Kageyama S; Kawauchi A; Inoue H
    Int J Oncol; 2021 Jul; 59(1):. PubMed ID: 33982789
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The microRNA-182-PDK4 axis regulates lung tumorigenesis by modulating pyruvate dehydrogenase and lipogenesis.
    Li G; Li M; Hu J; Lei R; Xiong H; Ji H; Yin H; Wei Q; Hu G
    Oncogene; 2017 Feb; 36(7):989-998. PubMed ID: 27641336
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Eicosapentaenoic Acid Inhibits
    Chiu CF; Hsu MI; Yeh HY; Park JM; Shen YS; Tung TH; Huang JJ; Wu HT; Huang SY
    Biomolecules; 2021 Mar; 11(3):. PubMed ID: 33801246
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The GTPase KRAS suppresses the p53 tumor suppressor by activating the NRF2-regulated antioxidant defense system in cancer cells.
    Yang H; Xiang S; Kazi A; Sebti SM
    J Biol Chem; 2020 Mar; 295(10):3055-3063. PubMed ID: 32001619
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Glutathione peroxidase 2 overexpression promotes malignant progression and cisplatin resistance of KRAS‑mutated lung cancer cells.
    Wang M; Chen X; Fu G; Ge M
    Oncol Rep; 2022 Dec; 48(6):. PubMed ID: 36222298
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oncogenic KRASG12D Reprograms Lipid Metabolism by Upregulating SLC25A1 to Drive Pancreatic Tumorigenesis.
    Zhang R; Peng X; Du JX; Boohaker R; Estevao IL; Grajeda BI; Cox MB; Almeida IC; Lu W
    Cancer Res; 2023 Nov; 83(22):3739-3752. PubMed ID: 37695315
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ARID1A suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/CDKN2A regulatory axis.
    Li ZY; Zhu SS; Chen XJ; Zhu J; Chen Q; Zhang YQ; Zhang CL; Guo TT; Zhang LM
    Biochem Biophys Res Commun; 2017 Nov; 493(2):1018-1025. PubMed ID: 28942143
    [TBL] [Abstract][Full Text] [Related]  

  • 10. KRAS-regulated glutamine metabolism requires UCP2-mediated aspartate transport to support pancreatic cancer growth.
    Raho S; Capobianco L; Malivindi R; Vozza A; Piazzolla C; De Leonardis F; Gorgoglione R; Scarcia P; Pezzuto F; Agrimi G; Barile SN; Pisano I; Reshkin SJ; Greco MR; Cardone RA; Rago V; Li Y; Marobbio CMT; Sommergruber W; Riley CL; Lasorsa FM; Mills E; Vegliante MC; De Benedetto GE; Fratantonio D; Palmieri L; Dolce V; Fiermonte G
    Nat Metab; 2020 Dec; 2(12):1373-1381. PubMed ID: 33230296
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oncogene KRAS activates fatty acid synthase, resulting in specific ERK and lipid signatures associated with lung adenocarcinoma.
    Gouw AM; Eberlin LS; Margulis K; Sullivan DK; Toal GG; Tong L; Zare RN; Felsher DW
    Proc Natl Acad Sci U S A; 2017 Apr; 114(17):4300-4305. PubMed ID: 28400509
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phellodendrine chloride suppresses proliferation of KRAS mutated pancreatic cancer cells through inhibition of nutrients uptake via macropinocytosis.
    Thu PM; Zheng ZG; Zhou YP; Wang YY; Zhang X; Jing D; Cheng HM; Li J; Li P; Xu X
    Eur J Pharmacol; 2019 May; 850():23-34. PubMed ID: 30716311
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.
    DeNicola GM; Karreth FA; Humpton TJ; Gopinathan A; Wei C; Frese K; Mangal D; Yu KH; Yeo CJ; Calhoun ES; Scrimieri F; Winter JM; Hruban RH; Iacobuzio-Donahue C; Kern SE; Blair IA; Tuveson DA
    Nature; 2011 Jul; 475(7354):106-9. PubMed ID: 21734707
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.
    Son J; Lyssiotis CA; Ying H; Wang X; Hua S; Ligorio M; Perera RM; Ferrone CR; Mullarky E; Shyh-Chang N; Kang Y; Fleming JB; Bardeesy N; Asara JM; Haigis MC; DePinho RA; Cantley LC; Kimmelman AC
    Nature; 2013 Apr; 496(7443):101-5. PubMed ID: 23535601
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.
    Padanad MS; Konstantinidou G; Venkateswaran N; Melegari M; Rindhe S; Mitsche M; Yang C; Batten K; Huffman KE; Liu J; Tang X; Rodriguez-Canales J; Kalhor N; Shay JW; Minna JD; McDonald J; Wistuba II; DeBerardinis RJ; Scaglioni PP
    Cell Rep; 2016 Aug; 16(6):1614-1628. PubMed ID: 27477280
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting metabolic reprogramming in KRAS-driven cancers.
    Kawada K; Toda K; Sakai Y
    Int J Clin Oncol; 2017 Aug; 22(4):651-659. PubMed ID: 28647837
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glycolysis-non-canonical glutamine dual-metabolism regulation nanodrug enhanced the phototherapy effect for pancreatic ductal adenocarcinoma treatment.
    Qiao J; Liu S; Huang Y; Zhu X; Xue C; Wang Y; Xiong H; Yao J
    J Colloid Interface Sci; 2024 Jul; 665():477-490. PubMed ID: 38429120
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Silencing expression of ribosomal protein L26 and L29 by RNA interfering inhibits proliferation of human pancreatic cancer PANC-1 cells.
    Li C; Ge M; Yin Y; Luo M; Chen D
    Mol Cell Biochem; 2012 Nov; 370(1-2):127-39. PubMed ID: 22868929
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A recombinant chimeric protein specifically induces mutant KRAS degradation and potently inhibits pancreatic tumor growth.
    Pan T; Zhang Y; Zhou N; He X; Chen C; Liang L; Duan X; Lin Y; Wu K; Zhang H
    Oncotarget; 2016 Jul; 7(28):44299-44309. PubMed ID: 27322423
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
    Hermann PC; Sancho P; Cañamero M; Martinelli P; Madriles F; Michl P; Gress T; de Pascual R; Gandia L; Guerra C; Barbacid M; Wagner M; Vieira CR; Aicher A; Real FX; Sainz B; Heeschen C
    Gastroenterology; 2014 Nov; 147(5):1119-33.e4. PubMed ID: 25127677
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.