159 related articles for article (PubMed ID: 35902550)
1. Selective targeting BMP2 and 4 in SMAD4 negative esophageal adenocarcinoma inhibits tumor growth and aggressiveness in preclinical models.
Li S; Hoefnagel SJM; Read M; Meijer S; van Berge Henegouwen MI; Gisbertz SS; Bonora E; Liu DSH; Phillips WA; Calpe S; Correia ACP; Sancho-Serra MDC; Mattioli S; Krishnadath KK;
Cell Oncol (Dordr); 2022 Aug; 45(4):639-658. PubMed ID: 35902550
[TBL] [Abstract][Full Text] [Related]
2. Effective Inhibition of Bone Morphogenetic Protein Function by Highly Specific Llama-Derived Antibodies.
Calpe S; Wagner K; El Khattabi M; Rutten L; Zimberlin C; Dolk E; Verrips CT; Medema JP; Spits H; Krishnadath KK
Mol Cancer Ther; 2015 Nov; 14(11):2527-40. PubMed ID: 26351325
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of BMP2-induced bone formation by the p65 subunit of NF-κB via an interaction with Smad4.
Hirata-Tsuchiya S; Fukushima H; Katagiri T; Ohte S; Shin M; Nagano K; Aoki K; Morotomi T; Sugiyama G; Nakatomi C; Kokabu S; Doi T; Takeuchi H; Ohya K; Terashita M; Hirata M; Kitamura C; Jimi E
Mol Endocrinol; 2014 Sep; 28(9):1460-70. PubMed ID: 25029242
[TBL] [Abstract][Full Text] [Related]
4. Smad4 is required to induce digit ray primordia and to initiate the aggregation and differentiation of chondrogenic progenitors in mouse limb buds.
Bénazet JD; Pignatti E; Nugent A; Unal E; Laurent F; Zeller R
Development; 2012 Nov; 139(22):4250-60. PubMed ID: 23034633
[TBL] [Abstract][Full Text] [Related]
5. BMP4 Signaling Is Able to Induce an Epithelial-Mesenchymal Transition-Like Phenotype in Barrett's Esophagus and Esophageal Adenocarcinoma through Induction of SNAIL2.
Kestens C; Siersema PD; Offerhaus GJ; van Baal JW
PLoS One; 2016; 11(5):e0155754. PubMed ID: 27191723
[TBL] [Abstract][Full Text] [Related]
6. A new function of BMP4: dual role for BMP4 in regulation of Sonic hedgehog expression in the mouse tooth germ.
Zhang Y; Zhang Z; Zhao X; Yu X; Hu Y; Geronimo B; Fromm SH; Chen YP
Development; 2000 Apr; 127(7):1431-43. PubMed ID: 10704389
[TBL] [Abstract][Full Text] [Related]
7. Loss of tumor-derived SMAD4 enhances primary tumor growth but not metastasis following BMP4 signalling.
Chi LH; Redfern AD; Roslan S; Street IP; Burrows AD; Anderson RL
Cell Commun Signal; 2024 Apr; 22(1):248. PubMed ID: 38689334
[TBL] [Abstract][Full Text] [Related]
8. Key elements of the BMP/SMAD pathway co-localize with CDX2 in intestinal metaplasia and regulate CDX2 expression in human gastric cell lines.
Barros R; Pereira B; Duluc I; Azevedo M; Mendes N; Camilo V; Jacobs RJ; Paulo P; Santos-Silva F; van Seuningen I; van den Brink GR; David L; Freund JN; Almeida R
J Pathol; 2008 Aug; 215(4):411-20. PubMed ID: 18498120
[TBL] [Abstract][Full Text] [Related]
9. Smad4 mediated BMP2 signal is essential for the regulation of GATA4 and Nkx2.5 by affecting the histone H3 acetylation in H9c2 cells.
Si L; Shi J; Gao W; Zheng M; Liu L; Zhu J; Tian J
Biochem Biophys Res Commun; 2014 Jul; 450(1):81-6. PubMed ID: 24866243
[TBL] [Abstract][Full Text] [Related]
10. Association of Bone Morphogenetic Protein (BMP)/Smad Signaling Pathway with Fracture Healing and Osteogenic Ability in Senile Osteoporotic Fracture in Humans and Rats.
Liu DB; Sui C; Wu TT; Wu LZ; Zhu YY; Ren ZH
Med Sci Monit; 2018 Jun; 24():4363-4371. PubMed ID: 29938690
[TBL] [Abstract][Full Text] [Related]
11. Comparison of newly developed anti-bone morphogenetic protein 4 llama-derived antibodies with commercially available BMP4 inhibitors.
Calpe S; Correia AC; Sancho-Serra Mdel C; Krishnadath KK
MAbs; 2016; 8(4):678-88. PubMed ID: 26967714
[TBL] [Abstract][Full Text] [Related]
12. A peptide that blocks the interaction of NF-κB p65 subunit with Smad4 enhances BMP2-induced osteogenesis.
Urata M; Kokabu S; Matsubara T; Sugiyama G; Nakatomi C; Takeuchi H; Hirata-Tsuchiya S; Aoki K; Tamura Y; Moriyama Y; Ayukawa Y; Matsuda M; Zhang M; Koyano K; Kitamura C; Jimi E
J Cell Physiol; 2018 Sep; 233(9):7356-7366. PubMed ID: 29663368
[TBL] [Abstract][Full Text] [Related]
13. Loss of BMP2, Smad8, and Smad4 expression in prostate cancer progression.
Horvath LG; Henshall SM; Kench JG; Turner JJ; Golovsky D; Brenner PC; O'Neill GF; Kooner R; Stricker PD; Grygiel JJ; Sutherland RL
Prostate; 2004 May; 59(3):234-42. PubMed ID: 15042598
[TBL] [Abstract][Full Text] [Related]
14. The effect of statins in colorectal cancer is mediated through the bone morphogenetic protein pathway.
Kodach LL; Bleuming SA; Peppelenbosch MP; Hommes DW; van den Brink GR; Hardwick JC
Gastroenterology; 2007 Oct; 133(4):1272-81. PubMed ID: 17919499
[TBL] [Abstract][Full Text] [Related]
15. Embryonic ablation of osteoblast Smad4 interrupts matrix synthesis in response to canonical Wnt signaling and causes an osteogenesis-imperfecta-like phenotype.
Salazar VS; Zarkadis N; Huang L; Norris J; Grimston SK; Mbalaviele G; Civitelli R
J Cell Sci; 2013 Nov; 126(Pt 21):4974-84. PubMed ID: 24006258
[TBL] [Abstract][Full Text] [Related]
16. Aberrant epithelial-mesenchymal Hedgehog signaling characterizes Barrett's metaplasia.
Wang DH; Clemons NJ; Miyashita T; Dupuy AJ; Zhang W; Szczepny A; Corcoran-Schwartz IM; Wilburn DL; Montgomery EA; Wang JS; Jenkins NA; Copeland NA; Harmon JW; Phillips WA; Watkins DN
Gastroenterology; 2010 May; 138(5):1810-22. PubMed ID: 20138038
[TBL] [Abstract][Full Text] [Related]
17. BMP2 differentially regulates the expression of Gremlin1 and Gremlin2, the negative regulators of BMP function, during osteoblast differentiation.
Suzuki D; Yamada A; Aizawa R; Funato S; Matsumoto T; Suzuki W; Takami M; Miyamoto Y; Suzawa T; Yamamoto M; Baba K; Kamijo R
Calcif Tissue Int; 2012 Jul; 91(1):88-96. PubMed ID: 22644325
[TBL] [Abstract][Full Text] [Related]
18. Bone morphogenetic protein-2 antagonizes bone morphogenetic protein-4 induced cardiomyocyte hypertrophy and apoptosis.
Lu J; Sun B; Huo R; Wang YC; Yang D; Xing Y; Xiao XL; Xie X; Dong DL
J Cell Physiol; 2014 Oct; 229(10):1503-10. PubMed ID: 24648278
[TBL] [Abstract][Full Text] [Related]
19. Esophageal Adenocarcinoma Cells and Xenograft Tumors Exposed to Erb-b2 Receptor Tyrosine Kinase 2 and 3 Inhibitors Activate Transforming Growth Factor Beta Signaling, Which Induces Epithelial to Mesenchymal Transition.
Ebbing EA; Steins A; Fessler E; Stathi P; Lesterhuis WJ; Krishnadath KK; Vermeulen L; Medema JP; Bijlsma MF; van Laarhoven HWM
Gastroenterology; 2017 Jul; 153(1):63-76.e14. PubMed ID: 28286209
[TBL] [Abstract][Full Text] [Related]
20. Hedgehog inhibition mediates radiation sensitivity in mouse xenograft models of human esophageal adenocarcinoma.
Teichman J; Dodbiba L; Thai H; Fleet A; Morey T; Liu L; McGregor M; Cheng D; Chen Z; Darling G; Brhane Y; Song Y; Espin-Garcia O; Xu W; Girgis H; Schwock J; MacKay H; Bristow R; Ailles L; Liu G
PLoS One; 2018; 13(5):e0194809. PubMed ID: 29715275
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
