BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 35902728)

  • 1. Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent manner.
    Woods ML; Weiss A; Sokol AM; Graumann J; Boettger T; Richter AM; Schermuly RT; Dammann RH
    Cancer Gene Ther; 2022 Dec; 29(12):1975-1987. PubMed ID: 35902728
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Epigenetic silencing of AATK in acinar to ductal metaplasia in murine model of pancreatic cancer.
    Ding LY; Hou YC; Kuo IY; Hsu TY; Tsai TC; Chang HW; Hsu WY; Tsao CC; Tian CC; Wang PS; Wang HC; Lee CT; Wang YC; Lin SH; Hughes MW; Chuang WJ; Lu PJ; Shan YS; Huang PH
    Clin Epigenetics; 2020 Jun; 12(1):87. PubMed ID: 32552862
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The apoptosis associated tyrosine kinase gene is frequently hypermethylated in human cancer and is regulated by epigenetic mechanisms.
    Haag T; Herkt CE; Walesch SK; Richter AM; Dammann RH
    Genes Cancer; 2014 Sep; 5(9-10):365-74. PubMed ID: 25352953
    [TBL] [Abstract][Full Text] [Related]  

  • 4. miR-1250-5p is a novel tumor suppressive intronic miRNA hypermethylated in non-Hodgkin's lymphoma: novel targets with impact on ERK signaling and cell migration.
    Zhang MY; Wang LQ; Chim CS
    Cell Commun Signal; 2021 May; 19(1):62. PubMed ID: 34044822
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetic inhibition of the atypical kinase Wee1 selectively drives apoptosis of p53 inactive tumor cells.
    Pappano WN; Zhang Q; Tucker LA; Tse C; Wang J
    BMC Cancer; 2014 Jun; 14():430. PubMed ID: 24927813
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Apoptosis-associated tyrosine kinase 1 inhibits growth and migration and promotes apoptosis in melanoma.
    Ma S; Rubin BP
    Lab Invest; 2014 Apr; 94(4):430-8. PubMed ID: 24589855
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HDAC2 overexpression confers oncogenic potential to human lung cancer cells by deregulating expression of apoptosis and cell cycle proteins.
    Jung KH; Noh JH; Kim JK; Eun JW; Bae HJ; Xie HJ; Chang YG; Kim MG; Park H; Lee JY; Nam SW
    J Cell Biochem; 2012 Jun; 113(6):2167-77. PubMed ID: 22492270
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antitumor effect of WEE1 blockade as monotherapy or in combination with cisplatin in urothelial cancer.
    Murakami K; Kita Y; Sakatani T; Hamada A; Mizuno K; Nakamura K; Takada H; Matsumoto K; Sano T; Goto T; Akamatsu S; Saito R; Tsuruyama T; Ogawa O; Kobayashi T
    Cancer Sci; 2021 Sep; 112(9):3669-3681. PubMed ID: 34212455
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Downregulation of AATK mediates microRNA-558-induced resistance of A549 cells to radiotherapy.
    Zhu RX; Song CH; Yang JS; Yi QT; Li BJ; Liu SH
    Mol Med Rep; 2016 Sep; 14(3):2846-52. PubMed ID: 27485693
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tumour suppressive effects of WEE1 gene silencing in breast cancer cells.
    Ghiasi N; Habibagahi M; Rosli R; Ghaderi A; Yusoff K; Hosseini A; Abdullah S; Jaberipour M
    Asian Pac J Cancer Prev; 2014 Jan; 14(11):6605-11. PubMed ID: 24377575
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Contribution of Intronic miR-338-3p and Its Hosting Gene AATK to Compensatory β-Cell Mass Expansion.
    Jacovetti C; Jimenez V; Ayuso E; Laybutt R; Peyot ML; Prentki M; Bosch F; Regazzi R
    Mol Endocrinol; 2015 May; 29(5):693-702. PubMed ID: 25751313
    [TBL] [Abstract][Full Text] [Related]  

  • 12. p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain.
    Ding Q; Grammer JR; Nelson MA; Guan JL; Stewart JE; Gladson CL
    J Biol Chem; 2005 Feb; 280(8):6802-15. PubMed ID: 15557280
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma.
    Chilà R; Basana A; Lupi M; Guffanti F; Gaudio E; Rinaldi A; Cascione L; Restelli V; Tarantelli C; Bertoni F; Damia G; Carrassa L
    Oncotarget; 2015 Feb; 6(5):3394-408. PubMed ID: 25428911
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of WEE1 confers resistance to PI3K inhibition in glioblastoma.
    Wu S; Wang S; Gao F; Li L; Zheng S; Yung WKA; Koul D
    Neuro Oncol; 2018 Jan; 20(1):78-91. PubMed ID: 29016926
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Wee1 inhibition potentiates Wip1-dependent p53-negative tumor cell death during chemotherapy.
    Clausse V; Goloudina AR; Uyanik B; Kochetkova EY; Richaud S; Fedorova OA; Hammann A; Bardou M; Barlev NA; Garrido C; Demidov ON
    Cell Death Dis; 2016 Apr; 7(4):e2195. PubMed ID: 27077811
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Apoptotic pathway induced by diallyl trisulfide in pancreatic cancer cells.
    Ma HB; Huang S; Yin XR; Zhang Y; Di ZL
    World J Gastroenterol; 2014 Jan; 20(1):193-203. PubMed ID: 24415872
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Wee-1 kinase inhibition overcomes cisplatin resistance associated with high-risk TP53 mutations in head and neck cancer through mitotic arrest followed by senescence.
    Osman AA; Monroe MM; Ortega Alves MV; Patel AA; Katsonis P; Fitzgerald AL; Neskey DM; Frederick MJ; Woo SH; Caulin C; Hsu TK; McDonald TO; Kimmel M; Meyn RE; Lichtarge O; Myers JN
    Mol Cancer Ther; 2015 Feb; 14(2):608-19. PubMed ID: 25504633
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A potential regulatory role for intronic microRNA-338-3p for its host gene encoding apoptosis-associated tyrosine kinase.
    Kos A; Olde Loohuis NF; Wieczorek ML; Glennon JC; Martens GJ; Kolk SM; Aschrafi A
    PLoS One; 2012; 7(2):e31022. PubMed ID: 22363537
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of p53 tumour suppressor target gene expression by the p52 NF-kappaB subunit.
    Schumm K; Rocha S; Caamano J; Perkins ND
    EMBO J; 2006 Oct; 25(20):4820-32. PubMed ID: 16990795
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of gene expression-based pharmacodynamic biomarker for a p53 context-specific anti-tumor drug Wee1 inhibitor.
    Mizuarai S; Yamanaka K; Itadani H; Arai T; Nishibata T; Hirai H; Kotani H
    Mol Cancer; 2009 Jun; 8():34. PubMed ID: 19500427
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.