172 related articles for article (PubMed ID: 35904556)
1. Peptide-to-Small Molecule: A Pharmacophore-Guided Small Molecule Lead Generation Strategy from High-Affinity Macrocyclic Peptides.
Yoshida S; Uehara S; Kondo N; Takahashi Y; Yamamoto S; Kameda A; Kawagoe S; Inoue N; Yamada M; Yoshimura N; Tachibana Y
J Med Chem; 2022 Aug; 65(15):10655-10673. PubMed ID: 35904556
[TBL] [Abstract][Full Text] [Related]
2. The RaPID Platform for the Discovery of Pseudo-Natural Macrocyclic Peptides.
Goto Y; Suga H
Acc Chem Res; 2021 Sep; 54(18):3604-3617. PubMed ID: 34505781
[TBL] [Abstract][Full Text] [Related]
3. Peptide-to-Small Molecule: Discovery of Non-Covalent, Active-Site Inhibitors of β-Herpesvirus Proteases.
Yoshida S; Sako Y; Nikaido E; Ueda T; Kozono I; Ichihashi Y; Nakahashi A; Onishi M; Yamatsu Y; Kato T; Nishikawa J; Tachibana Y
ACS Med Chem Lett; 2023 Nov; 14(11):1558-1566. PubMed ID: 37974946
[TBL] [Abstract][Full Text] [Related]
4. Macrocyclic Peptides as a Novel Class of NNMT Inhibitors: A SAR Study Aimed at Inhibitory Activity in the Cell.
Hayashi K; Uehara S; Yamamoto S; Cary DR; Nishikawa J; Ueda T; Ozasa H; Mihara K; Yoshimura N; Kawai T; Ono T; Yamamoto S; Fumoto M; Mikamiyama H
ACS Med Chem Lett; 2021 Jul; 12(7):1093-1101. PubMed ID: 34267879
[TBL] [Abstract][Full Text] [Related]
5. A pharmacophore-guided deep learning approach for bioactive molecular generation.
Zhu H; Zhou R; Cao D; Tang J; Li M
Nat Commun; 2023 Oct; 14(1):6234. PubMed ID: 37803000
[TBL] [Abstract][Full Text] [Related]
6. Natural product-like macrocyclic N-methyl-peptide inhibitors against a ubiquitin ligase uncovered from a ribosome-expressed de novo library.
Yamagishi Y; Shoji I; Miyagawa S; Kawakami T; Katoh T; Goto Y; Suga H
Chem Biol; 2011 Dec; 18(12):1562-70. PubMed ID: 22195558
[TBL] [Abstract][Full Text] [Related]
7. Macrocyclic peptides as allosteric inhibitors of nicotinamide
van Haren MJ; Zhang Y; Thijssen V; Buijs N; Gao Y; Mateuszuk L; Fedak FA; Kij A; Campagna R; Sartini D; Emanuelli M; Chlopicki S; Jongkees SAK; Martin NI
RSC Chem Biol; 2021 Oct; 2(5):1546-1555. PubMed ID: 34704059
[TBL] [Abstract][Full Text] [Related]
8. HELM-GPT: de novo macrocyclic peptide design using generative pre-trained transformer.
Xu X; Xu C; He W; Wei L; Li H; Zhou J; Zhang R; Wang Y; Xiong Y; Gao X
Bioinformatics; 2024 Jun; 40(6):. PubMed ID: 38867692
[TBL] [Abstract][Full Text] [Related]
9. Automatic generation of functional peptides with desired bioactivity and membrane permeability using Bayesian optimization.
Fukunaga I; Matsukiyo Y; Kaitoh K; Yamanishi Y
Mol Inform; 2024 Apr; 43(4):e202300148. PubMed ID: 38182544
[TBL] [Abstract][Full Text] [Related]
10. De Novo Discovery of Pseudo-Natural Prenylated Macrocyclic Peptide Ligands.
Inoue S; Nguyen DT; Hamada K; Okuma R; Okada C; Okada M; Abe I; Sengoku T; Goto Y; Suga H
Angew Chem Int Ed Engl; 2024 Jun; ():e202409973. PubMed ID: 38837490
[TBL] [Abstract][Full Text] [Related]
11. In vitro selection of multiple libraries created by genetic code reprogramming to discover macrocyclic peptides that antagonize VEGFR2 activity in living cells.
Kawakami T; Ishizawa T; Fujino T; Reid PC; Suga H; Murakami H
ACS Chem Biol; 2013; 8(6):1205-14. PubMed ID: 23517428
[TBL] [Abstract][Full Text] [Related]
12. RNA Display Methods for the Discovery of Bioactive Macrocycles.
Huang Y; Wiedmann MM; Suga H
Chem Rev; 2019 Sep; 119(17):10360-10391. PubMed ID: 30395448
[TBL] [Abstract][Full Text] [Related]
13. Affinity Maturation of Macrocyclic Peptide Modulators of Lys48-Linked Diubiquitin by a Twofold Strategy.
Huang Y; Nawatha M; Livneh I; Rogers JM; Sun H; Singh SK; Ciechanover A; Brik A; Suga H
Chemistry; 2020 Jun; 26(36):8022-8027. PubMed ID: 32105365
[TBL] [Abstract][Full Text] [Related]
14. Accelerated Identification of Cell Active KRAS Inhibitory Macrocyclic Peptides using Mixture Libraries and Automated Ligand Identification System (ALIS) Technology.
Garrigou M; Sauvagnat B; Duggal R; Boo N; Gopal P; Johnston JM; Partridge A; Sawyer T; Biswas K; Boyer N
J Med Chem; 2022 Jul; 65(13):8961-8974. PubMed ID: 35707970
[TBL] [Abstract][Full Text] [Related]
15. Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins.
Mihara E; Watanabe S; Bashiruddin NK; Nakamura N; Matoba K; Sano Y; Maini R; Yin Y; Sakai K; Arimori T; Matsumoto K; Suga H; Takagi J
Nat Commun; 2021 Mar; 12(1):1543. PubMed ID: 33750839
[TBL] [Abstract][Full Text] [Related]
16. Discovery of Functional Macrocyclic Peptides by Means of the RaPID System.
Tsiamantas C; Otero-Ramirez ME; Suga H
Methods Mol Biol; 2019; 2001():299-315. PubMed ID: 31134577
[TBL] [Abstract][Full Text] [Related]
17. Building on Success: A Bright Future for Peptide Therapeutics.
Angell Y; Holford M; Moos WH
Protein Pept Lett; 2018; 25(12):1044-1050. PubMed ID: 30430932
[TBL] [Abstract][Full Text] [Related]
18. Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase.
Neelakantan H; Wang HY; Vance V; Hommel JD; McHardy SF; Watowich SJ
J Med Chem; 2017 Jun; 60(12):5015-5028. PubMed ID: 28548833
[TBL] [Abstract][Full Text] [Related]
19. Discovery of De Novo Macrocyclic Peptides by Messenger RNA Display.
Peacock H; Suga H
Trends Pharmacol Sci; 2021 May; 42(5):385-397. PubMed ID: 33771353
[TBL] [Abstract][Full Text] [Related]
20. Selection-based discovery of druglike macrocyclic peptides.
Passioura T; Katoh T; Goto Y; Suga H
Annu Rev Biochem; 2014; 83():727-52. PubMed ID: 24580641
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]