These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Bedquiline Resistance Mutations: Correlations with Drug Exposures and Impact on the Proteome in M. tuberculosis. Xu J; Li D; Shi J; Wang B; Ge F; Guo Z; Mu X; Nuermberger E; Lu Y Antimicrob Agents Chemother; 2023 Jul; 67(7):e0153222. PubMed ID: 37255473 [TBL] [Abstract][Full Text] [Related]
6. Unexpected high prevalence of resistance-associated Rv0678 variants in MDR-TB patients without documented prior use of clofazimine or bedaquiline. Villellas C; Coeck N; Meehan CJ; Lounis N; de Jong B; Rigouts L; Andries K J Antimicrob Chemother; 2017 Mar; 72(3):684-690. PubMed ID: 28031270 [TBL] [Abstract][Full Text] [Related]
7. Towards a new combination therapy for tuberculosis with next generation benzothiazinones. Makarov V; Lechartier B; Zhang M; Neres J; van der Sar AM; Raadsen SA; Hartkoorn RC; Ryabova OB; Vocat A; Decosterd LA; Widmer N; Buclin T; Bitter W; Andries K; Pojer F; Dyson PJ; Cole ST EMBO Mol Med; 2014 Mar; 6(3):372-83. PubMed ID: 24500695 [TBL] [Abstract][Full Text] [Related]
8. Mutations in pepQ Confer Low-Level Resistance to Bedaquiline and Clofazimine in Mycobacterium tuberculosis. Almeida D; Ioerger T; Tyagi S; Li SY; Mdluli K; Andries K; Grosset J; Sacchettini J; Nuermberger E Antimicrob Agents Chemother; 2016 Aug; 60(8):4590-9. PubMed ID: 27185800 [TBL] [Abstract][Full Text] [Related]
9. Whole Genome Sequencing Identifies Novel Mutations Associated With Bedaquiline Resistance in Guo Q; Bi J; Lin Q; Ye T; Wang Z; Wang Z; Liu L; Zhang G Front Cell Infect Microbiol; 2022; 12():807095. PubMed ID: 35694543 [TBL] [Abstract][Full Text] [Related]
10. Mutation in Singh BK; Soneja M; Sharma R; Chaubey J; Kodan P; Jorwal P; Nischal N; Chandra S; Ramachandran R; Wig N Int J Mycobacteriol; 2020; 9(2):212-215. PubMed ID: 32474547 [TBL] [Abstract][Full Text] [Related]
11. Optimized Background Regimen for Treatment of Active Tuberculosis with the Next-Generation Benzothiazinone Macozinone (PBTZ169). Lupien A; Vocat A; Foo CS; Blattes E; Gillon JY; Makarov V; Cole ST Antimicrob Agents Chemother; 2018 Nov; 62(11):. PubMed ID: 30126954 [TBL] [Abstract][Full Text] [Related]
12. Population-level emergence of bedaquiline and clofazimine resistance-associated variants among patients with drug-resistant tuberculosis in southern Africa: a phenotypic and phylogenetic analysis. Nimmo C; Millard J; van Dorp L; Brien K; Moodley S; Wolf A; Grant AD; Padayatchi N; Pym AS; Balloux F; O'Donnell M Lancet Microbe; 2020 Aug; 1(4):e165-e174. PubMed ID: 32803174 [TBL] [Abstract][Full Text] [Related]
13. Clinical isolates of Mycobacterium tuberculosis in four European hospitals are uniformly susceptible to benzothiazinones. Pasca MR; Degiacomi G; Ribeiro AL; Zara F; De Mori P; Heym B; Mirrione M; Brerra R; Pagani L; Pucillo L; Troupioti P; Makarov V; Cole ST; Riccardi G Antimicrob Agents Chemother; 2010 Apr; 54(4):1616-8. PubMed ID: 20086151 [TBL] [Abstract][Full Text] [Related]
14. Primary Clofazimine and Bedaquiline Resistance among Isolates from Patients with Multidrug-Resistant Tuberculosis. Xu J; Wang B; Hu M; Huo F; Guo S; Jing W; Nuermberger E; Lu Y Antimicrob Agents Chemother; 2017 Jun; 61(6):. PubMed ID: 28320727 [TBL] [Abstract][Full Text] [Related]
15. Mutations associated with in vitro resistance to bedaquiline in Mycobacterium tuberculosis isolates in Australia. Martinez E; Hennessy D; Jelfs P; Crighton T; Chen SC; Sintchenko V Tuberculosis (Edinb); 2018 Jul; 111():31-34. PubMed ID: 30029911 [TBL] [Abstract][Full Text] [Related]
17. [The main results of clinical trials of the efficacy, safety and pharmacokinetics of the perspective anti-tuberculosis drug makozinone (PBTZ169)]. Mariandyshev AO; Khokhlov AL; Smerdin SV; Shcherbakova VS; Igumnova OV; Ozerova IV; Bolgarina AA; Nikitina NA Ter Arkh; 2020 Apr; 92(3):61-72. PubMed ID: 32598795 [TBL] [Abstract][Full Text] [Related]
18. Genetic variants and their association with phenotypic resistance to bedaquiline in Ismail N; Rivière E; Limberis J; Huo S; Metcalfe JZ; Warren RM; Van Rie A Lancet Microbe; 2021 Nov; 2(11):e604-e616. PubMed ID: 34796339 [TBL] [Abstract][Full Text] [Related]
19. Comparative Efficacy of the Novel Diarylquinoline TBAJ-587 and Bedaquiline against a Resistant Xu J; Converse PJ; Upton AM; Mdluli K; Fotouhi N; Nuermberger EL Antimicrob Agents Chemother; 2021 Mar; 65(4):. PubMed ID: 33526488 [TBL] [Abstract][Full Text] [Related]