These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. EWS-FLI1 regulates a transcriptional program in cooperation with Foxq1 in mouse Ewing sarcoma. Shimizu R; Tanaka M; Tsutsumi S; Aburatani H; Yamazaki Y; Homme M; Kitagawa Y; Nakamura T Cancer Sci; 2018 Sep; 109(9):2907-2918. PubMed ID: 29945296 [TBL] [Abstract][Full Text] [Related]
5. EWS/FLI is a Master Regulator of Metabolic Reprogramming in Ewing Sarcoma. Tanner JM; Bensard C; Wei P; Krah NM; Schell JC; Gardiner J; Schiffman J; Lessnick SL; Rutter J Mol Cancer Res; 2017 Nov; 15(11):1517-1530. PubMed ID: 28720588 [TBL] [Abstract][Full Text] [Related]
6. ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation. Gao Y; He XY; Wu XS; Huang YH; Toneyan S; Ha T; Ipsaro JJ; Koo PK; Joshua-Tor L; Bailey KM; Egeblad M; Vakoc CR Nat Cell Biol; 2023 Feb; 25(2):298-308. PubMed ID: 36658219 [TBL] [Abstract][Full Text] [Related]
7. Junction region of EWS-FLI1 fusion protein has a dominant negative effect in Ewing's sarcoma in vitro. Jully B; Vijayalakshmi R; Gopal G; Sabitha K; Rajkumar T BMC Cancer; 2012 Nov; 12():513. PubMed ID: 23145994 [TBL] [Abstract][Full Text] [Related]
8. Ablation of EWS-FLI1 by USP9X inhibition suppresses cancer cell growth in Ewing sarcoma. Wang S; Huo X; Yang Y; Mo Y; Kollipara RK; Kittler R Cancer Lett; 2023 Jan; 552():215984. PubMed ID: 36330954 [TBL] [Abstract][Full Text] [Related]
9. Suppression of FOXO1 is responsible for a growth regulatory repressive transcriptional sub-signature of EWS-FLI1 in Ewing sarcoma. Niedan S; Kauer M; Aryee DN; Kofler R; Schwentner R; Meier A; Pötschger U; Kontny U; Kovar H Oncogene; 2014 Jul; 33(30):3927-38. PubMed ID: 23995784 [TBL] [Abstract][Full Text] [Related]
10. EWS/FLI mediated reprogramming of 3D chromatin promotes an altered transcriptional state in Ewing sarcoma. Showpnil IA; Selich-Anderson J; Taslim C; Boone MA; Crow JC; Theisen ER; Lessnick SL Nucleic Acids Res; 2022 Sep; 50(17):9814-9837. PubMed ID: 36124657 [TBL] [Abstract][Full Text] [Related]
11. Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma. Hensel T; Giorgi C; Schmidt O; Calzada-Wack J; Neff F; Buch T; Niggli FK; Schäfer BW; Burdach S; Richter GH Oncotarget; 2016 Jan; 7(2):1451-63. PubMed ID: 26623725 [TBL] [Abstract][Full Text] [Related]
12. High-throughput RNAi screen in Ewing sarcoma cells identifies leucine rich repeats and WD repeat domain containing 1 (LRWD1) as a regulator of EWS-FLI1 driven cell viability. He T; Surdez D; Rantala JK; Haapa-Paananen S; Ban J; Kauer M; Tomazou E; Fey V; Alonso J; Kovar H; Delattre O; Iljin K Gene; 2017 Jan; 596():137-146. PubMed ID: 27760381 [TBL] [Abstract][Full Text] [Related]
13. ETS1, a Target Gene of the EWSR1::FLI1 Fusion Oncoprotein, Regulates the Expression of the Focal Adhesion Protein TENSIN3. Ebegboni VJ; Jones TL; Brownmiller T; Zhao PX; Pehrsson EC; Sundara Rajan S; Caplen NJ Mol Cancer Res; 2024 Jul; 22(7):625-641. PubMed ID: 38588446 [TBL] [Abstract][Full Text] [Related]
14. Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue. Gierisch ME; Pfistner F; Lopez-Garcia LA; Harder L; Schäfer BW; Niggli FK J Biol Chem; 2016 Dec; 291(52):26922-26933. PubMed ID: 27875302 [TBL] [Abstract][Full Text] [Related]
15. Therapeutic targeting the oncogenic driver EWSR1::FLI1 in Ewing sarcoma through inhibition of the FACT complex. Mo J; Tan K; Dong Y; Lu W; Liu F; Mei Y; Huang H; Zhao K; Lv Z; Ye Y; Tang Y Oncogene; 2023 Jan; 42(1):11-25. PubMed ID: 36357572 [TBL] [Abstract][Full Text] [Related]
16. Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma. Grohar PJ; Kim S; Rangel Rivera GO; Sen N; Haddock S; Harlow ML; Maloney NK; Zhu J; O'Neill M; Jones TL; Huppi K; Grandin M; Gehlhaus K; Klumpp-Thomas CA; Buehler E; Helman LJ; Martin SE; Caplen NJ Cell Rep; 2016 Jan; 14(3):598-610. PubMed ID: 26776507 [TBL] [Abstract][Full Text] [Related]
17. MiR-30a-5p connects EWS-FLI1 and CD99, two major therapeutic targets in Ewing tumor. Franzetti GA; Laud-Duval K; Bellanger D; Stern MH; Sastre-Garau X; Delattre O Oncogene; 2013 Aug; 32(33):3915-21. PubMed ID: 22986530 [TBL] [Abstract][Full Text] [Related]
18. Selective inhibition of HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma. García-Domínguez DJ; Hajji N; Sánchez-Molina S; Figuerola-Bou E; de Pablos RM; Espinosa-Oliva AM; Andrés-León E; Terrón-Camero LC; Flores-Campos R; Pascual-Pasto G; Robles MJ; Machado I; Llombart-Bosch A; Magagnoli G; Scotlandi K; Carcaboso ÁM; Mora J; de Álava E; Hontecillas-Prieto L Oncogene; 2021 Sep; 40(39):5843-5853. PubMed ID: 34345016 [TBL] [Abstract][Full Text] [Related]
19. Overexpression of HOX genes is prevalent in Ewing sarcoma and is associated with altered epigenetic regulation of developmental transcription programs. Svoboda LK; Harris A; Bailey NJ; Schwentner R; Tomazou E; von Levetzow C; Magnuson B; Ljungman M; Kovar H; Lawlor ER Epigenetics; 2014 Dec; 9(12):1613-25. PubMed ID: 25625846 [TBL] [Abstract][Full Text] [Related]
20. EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma. Gorthi A; Romero JC; Loranc E; Cao L; Lawrence LA; Goodale E; Iniguez AB; Bernard X; Masamsetti VP; Roston S; Lawlor ER; Toretsky JA; Stegmaier K; Lessnick SL; Chen Y; Bishop AJR Nature; 2018 Mar; 555(7696):387-391. PubMed ID: 29513652 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]