BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 35929395)

  • 1. Synthetic oleanane triterpenoid derivative CDDO-Me disrupts cellular bioenergetics to suppress pancreatic ductal adenocarcinoma via targeting SLC1A5.
    Akuetteh PDP; Huang H; Wu S; Zhou H; Jin G; Hong W; Yang H; Lan L; Shangguan F; Zhang Q
    J Biochem Mol Toxicol; 2022 Nov; 36(11):e23192. PubMed ID: 35929395
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Methyl 2-cyano-3,12-dioxooleana-1,9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: role of microRNA-27a.
    Jutooru I; Chadalapaka G; Abdelrahim M; Basha MR; Samudio I; Konopleva M; Andreeff M; Safe S
    Mol Pharmacol; 2010 Aug; 78(2):226-36. PubMed ID: 20488920
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells by independently targeting pro-survival Akt and mTOR.
    Deeb D; Gao X; Jiang H; Dulchavsky SA; Gautam SC
    Prostate; 2009 Jun; 69(8):851-60. PubMed ID: 19189297
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CDDO-Me inhibits tumor growth and prevents recurrence of pancreatic ductal adenocarcinoma.
    Gao X; Deeb D; Liu Y; Liu P; Zhang Y; Shaw J; Gautam SC
    Int J Oncol; 2015 Dec; 47(6):2100-6. PubMed ID: 26497549
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of telomerase activity by oleanane triterpenoid CDDO-Me in pancreatic cancer cells is ROS-dependent.
    Deeb D; Gao X; Liu Y; Varma NR; Arbab AS; Gautam SC
    Molecules; 2013 Mar; 18(3):3250-65. PubMed ID: 23486104
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Depletion of intracellular glutathione contributes to JNK-mediated death receptor 5 upregulation and apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me).
    Yue P; Zhou Z; Khuri FR; Sun SY
    Cancer Biol Ther; 2006 May; 5(5):492-7. PubMed ID: 16582599
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ROS mediate proapoptotic and antisurvival activity of oleanane triterpenoid CDDO-Me in ovarian cancer cells.
    Gao X; Liu Y; Deeb D; Liu P; Liu A; Arbab AS; Gautam SC
    Anticancer Res; 2013 Jan; 33(1):215-21. PubMed ID: 23267148
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection.
    Tran TA; McCoy MK; Sporn MB; Tansey MG
    J Neuroinflammation; 2008 May; 5():14. PubMed ID: 18474101
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of cell proliferation and induction of apoptosis by CDDO-Me in pancreatic cancer cells is ROS-dependent.
    Deeb D; Gao X; Liu YB; Gautam SC
    J Exp Ther Oncol; 2012; 10(1):51-64. PubMed ID: 22946344
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer.
    Samudio I; Konopleva M; Hail N; Shi YX; McQueen T; Hsu T; Evans R; Honda T; Gribble GW; Sporn M; Gilbert HF; Safe S; Andreeff M
    J Biol Chem; 2005 Oct; 280(43):36273-82. PubMed ID: 16118208
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling.
    Gao X; Liu Y; Deeb D; Arbab AS; Guo AM; Dulchavsky SA; Gautam SC
    Anticancer Res; 2011 Nov; 31(11):3673-81. PubMed ID: 22110186
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CDDO-Me: A Novel Synthetic Triterpenoid for the Treatment of Pancreatic Cancer.
    Deeb D; Gao X; Arbab AS; Barton K; Dulchavsky SA; Gautam SC
    Cancers (Basel); 2010 Dec; 2(4):1779-93. PubMed ID: 21799944
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Telomerase reverse transcriptase (TERT) is a therapeutic target of oleanane triterpenoid CDDO-Me in prostate cancer.
    Liu Y; Gao X; Deeb D; Arbab AS; Gautam SC
    Molecules; 2012 Dec; 17(12):14795-809. PubMed ID: 23519253
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells through a ROS-dependent mechanism.
    Deeb D; Gao X; Jiang H; Janic B; Arbab AS; Rojanasakul Y; Dulchavsky SA; Gautam SC
    Biochem Pharmacol; 2010 Feb; 79(3):350-60. PubMed ID: 19782051
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells.
    Kim KB; Lotan R; Yue P; Sporn MB; Suh N; Gribble GW; Honda T; Wu GS; Hong WK; Sun SY
    Mol Cancer Ther; 2002 Jan; 1(3):177-84. PubMed ID: 12467212
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway.
    Ryu K; Susa M; Choy E; Yang C; Hornicek FJ; Mankin HJ; Duan Z
    BMC Cancer; 2010 May; 10():187. PubMed ID: 20459702
    [TBL] [Abstract][Full Text] [Related]  

  • 17. c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells.
    Zou W; Liu X; Yue P; Zhou Z; Sporn MB; Lotan R; Khuri FR; Sun SY
    Cancer Res; 2004 Oct; 64(20):7570-8. PubMed ID: 15492284
    [TBL] [Abstract][Full Text] [Related]  

  • 18. c-FLIP downregulation contributes to apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in human lung cancer cells.
    Zou W; Chen S; Liu X; Yue P; Sporn MB; Khuri FR; Sun SY
    Cancer Biol Ther; 2007 Oct; 6(10):1614-20. PubMed ID: 18253090
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer.
    Hyer ML; Shi R; Krajewska M; Meyer C; Lebedeva IV; Fisher PB; Reed JC
    Cancer Res; 2008 Apr; 68(8):2927-33. PubMed ID: 18413762
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer.
    Nagaraj S; Youn JI; Weber H; Iclozan C; Lu L; Cotter MJ; Meyer C; Becerra CR; Fishman M; Antonia S; Sporn MB; Liby KT; Rawal B; Lee JH; Gabrilovich DI
    Clin Cancer Res; 2010 Mar; 16(6):1812-23. PubMed ID: 20215551
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.