188 related articles for article (PubMed ID: 35930852)
1. Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer's disease.
Macedo Vaz S; de Freitas Silva M; Dos Reis Rosa Franco G; Jorge R Guimarães M; Motta R da Silva F; Gonçalves Castro N; Alvim Guedes I; Dardenne LE; Amaral Alves M; Garrett da Costa R; Beserra Pinheiro G; Germino Veras L; Renata Mortari M; Pruccoli L; Tarozzi A; Viegas C
Bioorg Med Chem; 2022 Oct; 71():116952. PubMed ID: 35930852
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.
Dias Viegas FP; de Freitas Silva M; Divino da Rocha M; Castelli MR; Riquiel MM; Machado RP; Vaz SM; Simões de Lima LM; Mancini KC; Marques de Oliveira PC; Morais ÉP; Gontijo VS; da Silva FMR; D'Alincourt da Fonseca Peçanha D; Castro NG; Neves GA; Giusti-Paiva A; Vilela FC; Orlandi L; Camps I; Veloso MP; Leomil Coelho LF; Ionta M; Ferreira-Silva GÁ; Pereira RM; Dardenne LE; Guedes IA; de Oliveira Carneiro Junior W; Quaglio Bellozi PM; Pinheiro de Oliveira AC; Ferreira FF; Pruccoli L; Tarozzi A; Viegas C
Eur J Med Chem; 2018 Mar; 147():48-65. PubMed ID: 29421570
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and biological evaluation of novel coumarin derivatives as multifunctional ligands for the treatment of Alzheimer's disease.
Liu W; Wu L; Liu W; Tian L; Chen H; Wu Z; Wang N; Liu X; Qiu J; Feng X; Xu Z; Jiang X; Zhao Q
Eur J Med Chem; 2022 Nov; 242():114689. PubMed ID: 36007469
[TBL] [Abstract][Full Text] [Related]
4. Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases.
Ortiz CJC; Damasio CM; Pruccoli L; Nadur NF; de Azevedo LL; Guedes IA; Dardenne LE; Kümmerle AE; Tarozzi A; Viegas C
Neurochem Res; 2020 Dec; 45(12):3003-3020. PubMed ID: 33079324
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
Lan JS; Zhang T; Liu Y; Yang J; Xie SS; Liu J; Miao ZY; Ding Y
Eur J Med Chem; 2017 Jun; 133():184-196. PubMed ID: 28388521
[TBL] [Abstract][Full Text] [Related]
6. Design, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.
Chaves S; Resta S; Rinaldo F; Costa M; Josselin R; Gwizdala K; Piemontese L; Capriati V; Pereira-Santos AR; Cardoso SM; Santos MA
Molecules; 2020 Feb; 25(4):. PubMed ID: 32098407
[TBL] [Abstract][Full Text] [Related]
7. Discovery of novel hybrids containing clioquinol-1-benzyl-1,2,3,6-tetrahydropyridine as multi-target-directed ligands (MTDLs) against Alzheimer's disease.
Li X; Li T; Zhang P; Li X; Lu L; Sun Y; Zhang B; Allen S; White L; Phillips J; Zhu Z; Yao H; Xu J
Eur J Med Chem; 2022 Dec; 244():114841. PubMed ID: 36257284
[TBL] [Abstract][Full Text] [Related]
8. Discovery of novel series of 2-substituted benzo[d]oxazol-5-amine derivatives as multi-target directed ligands for the treatment of Alzheimer's disease.
Gutti G; Kakarla R; Kumar D; Beohar M; Ganeshpurkar A; Kumar A; Krishnamurthy S; Singh SK
Eur J Med Chem; 2019 Nov; 182():111613. PubMed ID: 31437780
[TBL] [Abstract][Full Text] [Related]
9. Donepezil-butylated hydroxytoluene (BHT) hybrids as Anti-Alzheimer's disease agents with cholinergic, antioxidant, and neuroprotective properties.
Cai P; Fang SQ; Yang HL; Yang XL; Liu QH; Kong LY; Wang XB
Eur J Med Chem; 2018 Sep; 157():161-176. PubMed ID: 30096650
[TBL] [Abstract][Full Text] [Related]
10. Flurbiprofen-chalcone hybrid Mannich base derivatives as balanced multifunctional agents against Alzheimer's disease: Design, synthesis and biological evaluation.
Tian C; Qiang X; Song Q; Cao Z; Ye C; He Y; Deng Y; Zhang L
Bioorg Chem; 2020 Jan; 94():103477. PubMed ID: 31818478
[TBL] [Abstract][Full Text] [Related]
11. Synthesis, biological evaluation and molecular modeling of benzofuran piperidine derivatives as Aβ antiaggregant.
Chowdhury SR; Gu J; Hu Y; Wang J; Lei S; Tavallaie MS; Lam C; Lu D; Jiang F; Fu L
Eur J Med Chem; 2021 Oct; 222():113541. PubMed ID: 34116326
[TBL] [Abstract][Full Text] [Related]
12. Rational Design and Multibiological Profiling of Novel Donepezil-Trolox Hybrids against Alzheimer's Disease, with Cholinergic, Antioxidant, Neuroprotective, and Cognition Enhancing Properties.
Cai P; Fang SQ; Yang XL; Wu JJ; Liu QH; Hong H; Wang XB; Kong LY
ACS Chem Neurosci; 2017 Nov; 8(11):2496-2511. PubMed ID: 28806057
[TBL] [Abstract][Full Text] [Related]
13. New Flavone-Cyanoacetamide Hybrids with a Combination of Cholinergic, Antioxidant, Modulation of β-Amyloid Aggregation, and Neuroprotection Properties as Innovative Multifunctional Therapeutic Candidates for Alzheimer's Disease and Unraveling Their Mechanism of Action with Acetylcholinesterase.
Basha SJ; Mohan P; Yeggoni DP; Babu ZR; Kumar PB; Rao AD; Subramanyam R; Damu AG
Mol Pharm; 2018 Jun; 15(6):2206-2223. PubMed ID: 29745222
[TBL] [Abstract][Full Text] [Related]
14. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents.
Košak U; Strašek N; Knez D; Jukič M; Žakelj S; Zahirović A; Pišlar A; Brazzolotto X; Nachon F; Kos J; Gobec S
Eur J Med Chem; 2020 Jul; 197():112282. PubMed ID: 32380361
[TBL] [Abstract][Full Text] [Related]
15. Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors:
Makhaeva GF; Kovaleva NV; Boltneva NP; Rudakova EV; Lushchekina SV; Astakhova TY; Serkov IV; Proshin AN; Radchenko EV; Palyulin VA; Korabecny J; Soukup O; Bachurin SO; Richardson RJ
Molecules; 2022 Feb; 27(3):. PubMed ID: 35164325
[TBL] [Abstract][Full Text] [Related]
16. Novel salicylamide derivatives as potent multifunctional agents for the treatment of Alzheimer's disease: Design, synthesis and biological evaluation.
Song Q; Li Y; Cao Z; Qiang X; Tan Z; Deng Y
Bioorg Chem; 2019 Mar; 84():137-149. PubMed ID: 30500523
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis and evaluation of chalcone Mannich base derivatives as multifunctional agents for the potential treatment of Alzheimer's disease.
Zhang X; Song Q; Cao Z; Li Y; Tian C; Yang Z; Zhang H; Deng Y
Bioorg Chem; 2019 Jun; 87():395-408. PubMed ID: 30921741
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis, and biological evaluation of ferulic acid based 1,3,4-oxadiazole hybrids as multifunctional therapeutics for the treatment of Alzheimer's disease.
Tripathi A; Choubey PK; Sharma P; Seth A; Saraf P; Shrivastava SK
Bioorg Chem; 2020 Jan; 95():103506. PubMed ID: 31887472
[TBL] [Abstract][Full Text] [Related]
19. Design and synthesis of novel tacrine-dipicolylamine dimers that are multiple-target-directed ligands with potential to treat Alzheimer's disease.
Zhang P; Wang Z; Mou C; Zou J; Xie Y; Liu Z; Benjamin Naman C; Mao Y; Wei J; Huang X; Dong J; Yang M; Wang N; Jin H; Liu F; Lin D; Liu H; Zhou F; He S; Zhang B; Cui W
Bioorg Chem; 2021 Nov; 116():105387. PubMed ID: 34628225
[TBL] [Abstract][Full Text] [Related]
20. Development of naringenin-O-carbamate derivatives as multi-target-directed liagnds for the treatment of Alzheimer's disease.
Mi J; He Y; Yang J; Zhou Y; Zhu G; Wu A; Liu W; Sang Z
Bioorg Med Chem Lett; 2022 Mar; 60():128574. PubMed ID: 35065231
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]