295 related articles for article (PubMed ID: 35931030)
1. Lipid accumulation induced by APOE4 impairs microglial surveillance of neuronal-network activity.
Victor MB; Leary N; Luna X; Meharena HS; Scannail AN; Bozzelli PL; Samaan G; Murdock MH; von Maydell D; Effenberger AH; Cerit O; Wen HL; Liu L; Welch G; Bonner M; Tsai LH
Cell Stem Cell; 2022 Aug; 29(8):1197-1212.e8. PubMed ID: 35931030
[TBL] [Abstract][Full Text] [Related]
2. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk.
Huang YA; Zhou B; Nabet AM; Wernig M; Südhof TC
J Neurosci; 2019 Sep; 39(37):7408-7427. PubMed ID: 31331998
[TBL] [Abstract][Full Text] [Related]
3. Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer's disease.
Liu CC; Wang N; Chen Y; Inoue Y; Shue F; Ren Y; Wang M; Qiao W; Ikezu TC; Li Z; Zhao J; Martens Y; Doss SV; Rosenberg CL; Jeevaratnam S; Jia L; Raulin AC; Qi F; Zhu Y; Alnobani A; Knight J; Chen Y; Linares C; Kurti A; Fryer JD; Zhang B; Wu LJ; Kim BYS; Bu G
Nat Immunol; 2023 Nov; 24(11):1854-1866. PubMed ID: 37857825
[TBL] [Abstract][Full Text] [Related]
4. APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.
Lin YT; Seo J; Gao F; Feldman HM; Wen HL; Penney J; Cam HP; Gjoneska E; Raja WK; Cheng J; Rueda R; Kritskiy O; Abdurrob F; Peng Z; Milo B; Yu CJ; Elmsaouri S; Dey D; Ko T; Yankner BA; Tsai LH
Neuron; 2018 Jun; 98(6):1141-1154.e7. PubMed ID: 29861287
[TBL] [Abstract][Full Text] [Related]
5. APOE4 genotype and aging impair injury-induced microglial behavior in brain slices, including toward Aβ, through P2RY12.
Sepulveda J; Kim JY; Binder J; Vicini S; Rebeck GW
Mol Neurodegener; 2024 Mar; 19(1):24. PubMed ID: 38468308
[TBL] [Abstract][Full Text] [Related]
6. APOE genotype and sex affect microglial interactions with plaques in Alzheimer's disease mice.
Stephen TL; Cacciottolo M; Balu D; Morgan TE; LaDu MJ; Finch CE; Pike CJ
Acta Neuropathol Commun; 2019 May; 7(1):82. PubMed ID: 31113487
[TBL] [Abstract][Full Text] [Related]
7.
Sienski G; Narayan P; Bonner JM; Kory N; Boland S; Arczewska AA; Ralvenius WT; Akay L; Lockshin E; He L; Milo B; Graziosi A; Baru V; Lewis CA; Kellis M; Sabatini DM; Tsai LH; Lindquist S
Sci Transl Med; 2021 Mar; 13(583):. PubMed ID: 33658354
[TBL] [Abstract][Full Text] [Related]
8. Astrocytic APOE4 genotype-mediated negative impacts on synaptic architecture in human pluripotent stem cell model.
Watanabe H; Murakami R; Tsumagari K; Morimoto S; Hashimoto T; Imaizumi K; Sonn I; Yamada K; Saito Y; Murayama S; Iwatsubo T; Okano H
Stem Cell Reports; 2023 Sep; 18(9):1854-1869. PubMed ID: 37657448
[TBL] [Abstract][Full Text] [Related]
9. Association between abnormal lipid metabolism and Alzheimer's disease: New research has revealed significant findings on the APOE4 genotype in microglia.
Hu X; Ma YN; Xia Y
Biosci Trends; 2024 Jun; 18(2):195-197. PubMed ID: 38631884
[TBL] [Abstract][Full Text] [Related]
10. Opposing effects of apoE2 and apoE4 on microglial activation and lipid metabolism in response to demyelination.
Wang N; Wang M; Jeevaratnam S; Rosenberg C; Ikezu TC; Shue F; Doss SV; Alnobani A; Martens YA; Wren M; Asmann YW; Zhang B; Bu G; Liu CC
Mol Neurodegener; 2022 Nov; 17(1):75. PubMed ID: 36419137
[TBL] [Abstract][Full Text] [Related]
11. APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes.
de Leeuw SM; Kirschner AWT; Lindner K; Rust R; Budny V; Wolski WE; Gavin AC; Nitsch RM; Tackenberg C
Stem Cell Reports; 2022 Jan; 17(1):110-126. PubMed ID: 34919811
[TBL] [Abstract][Full Text] [Related]
12. Microglial APOE4: more is less and less is more.
Eskandari-Sedighi G; Blurton-Jones M
Mol Neurodegener; 2023 Dec; 18(1):99. PubMed ID: 38115077
[TBL] [Abstract][Full Text] [Related]
13. In Thai Nationals, the ApoE4 Allele Affects Multiple Domains of Neuropsychological, Biobehavioral, and Social Functioning Thereby Contributing to Alzheimer's Disorder, while the ApoE3 Allele Protects Against Neuropsychiatric Symptoms and Psychosocial Deficits.
Tangwongchai S; Supasitthumrong T; Hemrunroj S; Tunvirachaisakul C; Chuchuen P; Houngngam N; Snabboon T; Tawankanjanachot I; Likitchareon Y; Phanthumchindad K; Maes M
Mol Neurobiol; 2018 Aug; 55(8):6449-6462. PubMed ID: 29307083
[TBL] [Abstract][Full Text] [Related]
14. Microglia Depletion Reduces Human Neuronal APOE4-Driven Pathologies in a Chimeric Alzheimer's Disease Model.
Rao A; Chen N; Kim MJ; Blumenfeld J; Yip O; Hao Y; Liang Z; Nelson MR; Koutsodendris N; Grone B; Ding L; Yoon SY; Arriola P; Huang Y
bioRxiv; 2023 Nov; ():. PubMed ID: 38014339
[TBL] [Abstract][Full Text] [Related]
15. APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress.
Colton CA; Brown CM; Cook D; Needham LK; Xu Q; Czapiga M; Saunders AM; Schmechel DE; Rasheed K; Vitek MP
Neurobiol Aging; 2002; 23(5):777-85. PubMed ID: 12392781
[TBL] [Abstract][Full Text] [Related]
16. APOE4/4 is linked to damaging lipid droplets in Alzheimer's disease microglia.
Haney MS; Pálovics R; Munson CN; Long C; Johansson PK; Yip O; Dong W; Rawat E; West E; Schlachetzki JCM; Tsai A; Guldner IH; Lamichhane BS; Smith A; Schaum N; Calcuttawala K; Shin A; Wang YH; Wang C; Koutsodendris N; Serrano GE; Beach TG; Reiman EM; Glass CK; Abu-Remaileh M; Enejder A; Huang Y; Wyss-Coray T
Nature; 2024 Apr; 628(8006):154-161. PubMed ID: 38480892
[TBL] [Abstract][Full Text] [Related]
17. Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice.
Fitz NF; Cronican AA; Saleem M; Fauq AH; Chapman R; Lefterov I; Koldamova R
J Neurosci; 2012 Sep; 32(38):13125-36. PubMed ID: 22993429
[TBL] [Abstract][Full Text] [Related]
18. Intraneuronal amyloid-beta plays a role in mediating the synergistic pathological effects of apoE4 and environmental stimulation.
Levi O; Dolev I; Belinson H; Michaelson DM
J Neurochem; 2007 Nov; 103(3):1031-40. PubMed ID: 17666042
[TBL] [Abstract][Full Text] [Related]
19. Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.
Brecht WJ; Harris FM; Chang S; Tesseur I; Yu GQ; Xu Q; Dee Fish J; Wyss-Coray T; Buttini M; Mucke L; Mahley RW; Huang Y
J Neurosci; 2004 Mar; 24(10):2527-34. PubMed ID: 15014128
[TBL] [Abstract][Full Text] [Related]
20. Cholesterol and matrisome pathways dysregulated in astrocytes and microglia.
Tcw J; Qian L; Pipalia NH; Chao MJ; Liang SA; Shi Y; Jain BR; Bertelsen SE; Kapoor M; Marcora E; Sikora E; Andrews EJ; Martini AC; Karch CM; Head E; Holtzman DM; Zhang B; Wang M; Maxfield FR; Poon WW; Goate AM
Cell; 2022 Jun; 185(13):2213-2233.e25. PubMed ID: 35750033
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
