BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 3593407)

  • 1. Effects of methotrexate and other antifolates on the growth and dihydrofolate reductase activity of Leishmania promastigotes.
    Scott DA; Coombs GH; Sanderson BE
    Biochem Pharmacol; 1987 Jun; 36(12):2043-5. PubMed ID: 3593407
    [No Abstract]   [Full Text] [Related]  

  • 2. Exploring the ability of dihydropyrimidine-5-carboxamide and 5-benzyl-2,4-diaminopyrimidine-based analogues for the selective inhibition of L. major dihydrofolate reductase.
    Bibi M; Qureshi NA; Sadiq A; Farooq U; Hassan A; Shaheen N; Asghar I; Umer D; Ullah A; Khan FA; Salman M; Bibi A; Rashid U
    Eur J Med Chem; 2021 Jan; 210():112986. PubMed ID: 33187806
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluation of potent inhibitors of dihydrofolate reductase in a culture model for growth of Pneumocystis carinii.
    Bartlett MS; Shaw M; Navaran P; Smith JW; Queener SF
    Antimicrob Agents Chemother; 1995 Nov; 39(11):2436-41. PubMed ID: 8585722
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dihydrofolate reductase from Eimeria tenella: rationalization of chemotherapeutic efficacy of pyrimethamine.
    Wang CC; Stotish RL; Poe M
    J Protozool; 1975 Nov; 22(4):564-8. PubMed ID: 1059772
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting pteridine reductase 1 and dihydrofolate reductase: the old is a new trend for leishmaniasis drug discovery.
    das Neves GM; Kagami LP; Gonçalves IL; Eifler-Lima VL
    Future Med Chem; 2019 Aug; 11(16):2107-2130. PubMed ID: 31370699
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Elevation of dihydrofolate reductase, thymidylate synthetase, and thymidine kinase in cultured mammalian cells after exposure to folate antagonists.
    Chello PL; McQueen CA; DeAngelis LM; Bertino JR
    Cancer Res; 1976 Jul; 36(7 PT 1):2442-9. PubMed ID: 1277151
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biochemical and genetic tests for inhibitors of Leishmania pteridine pathways.
    Hardy LW; Matthews W; Nare B; Beverley SM
    Exp Parasitol; 1997 Nov; 87(3):157-69. PubMed ID: 9371081
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Toxicity of methotrexate and metoprine in a dihydrofolate reductase gene-amplified mouse cell line.
    Hamrell M; Laszlo J; Brown OE; Sedwick WD
    Mol Pharmacol; 1981 Nov; 20(3):637-43. PubMed ID: 7329406
    [No Abstract]   [Full Text] [Related]  

  • 9. Changes in enzyme activity and expression of DHFR of Toxoplasma gondii by antifolates.
    Baek EJ; Nam HW
    Korean J Parasitol; 1998 Sep; 36(3):191-8. PubMed ID: 9755590
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vivo measurement of dihydrofolate reductase and its inhibition by antifolates.
    Bowers SW; Duch DS
    Anal Biochem; 1988 Jul; 172(1):169-75. PubMed ID: 3189762
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of dihydrofolate reductase and cell growth by antifolates in a methotrexate-resistant cell line.
    Hamrell MR
    Oncology; 1984; 41(5):343-8. PubMed ID: 6540852
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of Pneumocystis dihydrofolate reductase by analogs of pyrimethamine, methotrexate and trimetrexate.
    Queener SF
    J Protozool; 1991; 38(6):154S-157S. PubMed ID: 1840146
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Kinetic and molecular properties of the dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant clones of the human malaria parasite Plasmodium falciparum.
    Chen GX; Mueller C; Wendlinger M; Zolg JW
    Mol Pharmacol; 1987 Apr; 31(4):430-7. PubMed ID: 3553892
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dihydrofolate reductase from Trypanosoma equiperdum. I. Isolation, partial purification, and properties.
    Jaffe JJ; McCormack JJ
    Mol Pharmacol; 1967 Jul; 3(4):359-69. PubMed ID: 4382281
    [No Abstract]   [Full Text] [Related]  

  • 15. Effects of methotrexate esters and other lipophilic antifolates on methotrexate-resistant human leukemic lymphoblasts.
    Rosowsky A; Lazarus H; Yuan GC; Beltz WR; Mangini L; Abelson HT; Modest EJ; Frei E
    Biochem Pharmacol; 1980 Feb; 29(4):648-52. PubMed ID: 6929188
    [No Abstract]   [Full Text] [Related]  

  • 16. Molecular cloning and expression of the dihydrofolate reductase (DHFR) gene from adult buffalo fly (Haematobia irritans exigua): effects of antifolates.
    Elvin CM; Liyou NE; Pearson R; Kemp DH; Dixon NE
    Insect Mol Biol; 2003 Apr; 12(2):173-83. PubMed ID: 12653939
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Two different species of dihydrofolate reductase in mammalian cells differentially resistant to amethopterin and methasquin.
    Albrecht AM; Biedler JL; Hutchison DJ
    Cancer Res; 1972 Jul; 32(7):1539-46. PubMed ID: 4402276
    [No Abstract]   [Full Text] [Related]  

  • 18. Activity of antifolates against Pneumocystis carinii dihydrofolate reductase and identification of a potent new agent.
    Allegra CJ; Kovacs JA; Drake JC; Swan JC; Chabner BA; Masur H
    J Exp Med; 1987 Mar; 165(3):926-31. PubMed ID: 2950200
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Drosophila dihydrofolate reductase mutations confer antifolate resistance to mammalian cells.
    Affleck JG; Al-Batayneh KM; Neumann K; Cole SP; Walker VK
    Eur J Pharmacol; 2006 Jan; 529(1-3):71-8. PubMed ID: 16325803
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Two different effects of mutation on the binding of folate antagonists by a microbial dihydrofolate reductase.
    Sirotnak FM
    Biochim Biophys Acta; 1973 Mar; 302(1):13-23. PubMed ID: 4144236
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 9.