BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 35941660)

  • 1. Identification of TMEM129, encoding a ubiquitin-protein ligase, as an effector gene of osteoarthritis genetic risk.
    Brumwell A; Aubourg G; Hussain J; Parker E; Deehan DJ; Rice SJ; Loughlin J
    Arthritis Res Ther; 2022 Aug; 24(1):189. PubMed ID: 35941660
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic and Epigenetic Interplay Within a COLGALT2 Enhancer Associated With Osteoarthritis.
    Kehayova YS; Watson E; Wilkinson JM; Loughlin J; Rice SJ
    Arthritis Rheumatol; 2021 Oct; 73(10):1856-1865. PubMed ID: 33760386
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multi-Tissue Epigenetic and Gene Expression Analysis Combined With Epigenome Modulation Identifies RWDD2B as a Target of Osteoarthritis Susceptibility.
    Parker E; Hofer IMJ; Rice SJ; Earl L; Anjum SA; Deehan DJ; Loughlin J
    Arthritis Rheumatol; 2021 Jan; 73(1):100-109. PubMed ID: 32755071
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Osteoarthritis genetic risk acting on the galactosyltransferase gene COLGALT2 has opposing functional effects in articulating joint tissues.
    Kehayova YS; Wilkinson JM; Rice SJ; Loughlin J
    Arthritis Res Ther; 2023 May; 25(1):83. PubMed ID: 37208701
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetic and Epigenetic Fine-Tuning of TGFB1 Expression Within the Human Osteoarthritic Joint.
    Rice SJ; Roberts JB; Tselepi M; Brumwell A; Falk J; Steven C; Loughlin J
    Arthritis Rheumatol; 2021 Oct; 73(10):1866-1877. PubMed ID: 33760378
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mediation of the Same Epigenetic and Transcriptional Effect by Independent Osteoarthritis Risk-Conferring Alleles on a Shared Target Gene, COLGALT2.
    Kehayova YS; Wilkinson JM; Rice SJ; Loughlin J
    Arthritis Rheumatol; 2023 Jun; 75(6):910-922. PubMed ID: 36538011
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prioritization of PLEC and GRINA as Osteoarthritis Risk Genes Through the Identification and Characterization of Novel Methylation Quantitative Trait Loci.
    Rice SJ; Tselepi M; Sorial AK; Aubourg G; Shepherd C; Almarza D; Skelton AJ; Pangou I; Deehan D; Reynard LN; Loughlin J
    Arthritis Rheumatol; 2019 Aug; 71(8):1285-1296. PubMed ID: 30730609
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383.
    Reynard LN; Bui C; Syddall CM; Loughlin J
    Hum Genet; 2014 Aug; 133(8):1059-73. PubMed ID: 24861163
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Correlation of the osteoarthritis susceptibility variants that map to chromosome 20q13 with an expression quantitative trait locus operating on NCOA3 and with functional variation at the polymorphism rs116855380.
    Gee F; Rushton MD; Loughlin J; Reynard LN
    Arthritis Rheumatol; 2015 Nov; 67(11):2923-32. PubMed ID: 26211391
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Methylation quantitative trait locus analysis of osteoarthritis links epigenetics with genetic risk.
    Rushton MD; Reynard LN; Young DA; Shepherd C; Aubourg G; Gee F; Darlay R; Deehan D; Cordell HJ; Loughlin J
    Hum Mol Genet; 2015 Dec; 24(25):7432-44. PubMed ID: 26464490
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.
    Olsson AH; Volkov P; Bacos K; Dayeh T; Hall E; Nilsson EA; Ladenvall C; Rönn T; Ling C
    PLoS Genet; 2014 Nov; 10(11):e1004735. PubMed ID: 25375650
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Multi-tissue epigenetic analysis of the osteoarthritis susceptibility locus mapping to the plectin gene PLEC.
    Sorial AK; Hofer IMJ; Tselepi M; Cheung K; Parker E; Deehan DJ; Rice SJ; Loughlin J
    Osteoarthritis Cartilage; 2020 Nov; 28(11):1448-1458. PubMed ID: 32580029
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery and analysis of methylation quantitative trait loci (mQTLs) mapping to novel osteoarthritis genetic risk signals.
    Rice SJ; Cheung K; Reynard LN; Loughlin J
    Osteoarthritis Cartilage; 2019 Oct; 27(10):1545-1556. PubMed ID: 31173883
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Incorporation of DNA methylation quantitative trait loci (mQTLs) in epigenome-wide association analysis: application to birthweight effects in neonatal whole blood.
    Li S; Mancuso N; Metayer C; Ma X; de Smith AJ; Wiemels JL
    Clin Epigenetics; 2022 Dec; 14(1):158. PubMed ID: 36457128
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Parent of origin genetic effects on methylation in humans are common and influence complex trait variation.
    Zeng Y; Amador C; Xia C; Marioni R; Sproul D; Walker RM; Morris SW; Bretherick A; Canela-Xandri O; Boutin TS; Clark DW; Campbell A; Rawlik K; Hayward C; Nagy R; Tenesa A; Porteous DJ; Wilson JF; Deary IJ; Evans KL; McIntosh AM; Navarro P; Haley CS
    Nat Commun; 2019 Mar; 10(1):1383. PubMed ID: 30918249
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An epigenome-wide view of osteoarthritis in primary tissues.
    Kreitmaier P; Suderman M; Southam L; Coutinho de Almeida R; Hatzikotoulas K; Meulenbelt I; Steinberg J; Relton CL; Wilkinson JM; Zeggini E
    Am J Hum Genet; 2022 Jul; 109(7):1255-1271. PubMed ID: 35679866
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome.
    Cheung WA; Shao X; Morin A; Siroux V; Kwan T; Ge B; Aïssi D; Chen L; Vasquez L; Allum F; Guénard F; Bouzigon E; Simon MM; Boulier E; Redensek A; Watt S; Datta A; Clarke L; Flicek P; Mead D; Paul DS; Beck S; Bourque G; Lathrop M; Tchernof A; Vohl MC; Demenais F; Pin I; Downes K; Stunnenberg HG; Soranzo N; Pastinen T; Grundberg E
    Genome Biol; 2017 Mar; 18(1):50. PubMed ID: 28283040
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of methylation quantitative trait loci (mQTLs) influencing promoter DNA methylation of alcohol dependence risk genes.
    Zhang H; Wang F; Kranzler HR; Yang C; Xu H; Wang Z; Zhao H; Gelernter J
    Hum Genet; 2014 Sep; 133(9):1093-104. PubMed ID: 24889829
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of genome-methylome interactions in 22 nuclear pedigrees.
    Plongthongkum N; van Eijk KR; de Jong S; Wang T; Sul JH; Boks MP; Kahn RS; Fung HL; Ophoff RA; Zhang K
    PLoS One; 2014; 9(7):e99313. PubMed ID: 25019935
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of a novel, methylation-dependent, RUNX2 regulatory region associated with osteoarthritis risk.
    Rice SJ; Aubourg G; Sorial AK; Almarza D; Tselepi M; Deehan DJ; Reynard LN; Loughlin J
    Hum Mol Genet; 2018 Oct; 27(19):3464-3474. PubMed ID: 30010910
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.