BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 35943292)

  • 1. Endoplasmic reticulum stress induces Alzheimer disease-like phenotypes in the neuron derived from the induced pluripotent stem cell with D678H mutation on amyloid precursor protein.
    Devina T; Wong YH; Hsiao CW; Li YJ; Lien CC; Cheng IH
    J Neurochem; 2022 Oct; 163(1):26-39. PubMed ID: 35943292
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modeling Alzheimer's Disease by Induced Pluripotent Stem Cells Carrying APP D678H Mutation.
    Chang KH; Lee-Chen GJ; Huang CC; Lin JL; Chen YJ; Wei PC; Lo YS; Yao CF; Kuo MW; Chen CM
    Mol Neurobiol; 2019 Jun; 56(6):3972-3983. PubMed ID: 30238389
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ.
    Kwart D; Gregg A; Scheckel C; Murphy EA; Paquet D; Duffield M; Fak J; Olsen O; Darnell RB; Tessier-Lavigne M
    Neuron; 2019 Oct; 104(2):256-270.e5. PubMed ID: 31416668
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
    Kimura A; Hata S; Suzuki T
    J Biol Chem; 2016 Nov; 291(46):24041-24053. PubMed ID: 27687728
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein.
    Maloney JA; Bainbridge T; Gustafson A; Zhang S; Kyauk R; Steiner P; van der Brug M; Liu Y; Ernst JA; Watts RJ; Atwal JK
    J Biol Chem; 2014 Nov; 289(45):30990-1000. PubMed ID: 25253696
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation.
    Ochalek A; Mihalik B; Avci HX; Chandrasekaran A; Téglási A; Bock I; Giudice ML; Táncos Z; Molnár K; László L; Nielsen JE; Holst B; Freude K; Hyttel P; Kobolák J; Dinnyés A
    Alzheimers Res Ther; 2017 Dec; 9(1):90. PubMed ID: 29191219
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ER stress is not elevated in the 5XFAD mouse model of Alzheimer's disease.
    Sadleir KR; Popovic J; Vassar R
    J Biol Chem; 2018 Nov; 293(48):18434-18443. PubMed ID: 30315100
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation.
    Marwarha G; Rostad S; Lilek J; Kleinjan M; Schommer J; Ghribi O
    J Alzheimers Dis; 2017; 57(3):907-925. PubMed ID: 28304295
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
    Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
    Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons.
    Muratore CR; Rice HC; Srikanth P; Callahan DG; Shin T; Benjamin LN; Walsh DM; Selkoe DJ; Young-Pearse TL
    Hum Mol Genet; 2014 Jul; 23(13):3523-36. PubMed ID: 24524897
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BACE1 Cleavage Site Selection Critical for Amyloidogenesis and Alzheimer's Pathogenesis.
    Zhang S; Wang Z; Cai F; Zhang M; Wu Y; Zhang J; Song W
    J Neurosci; 2017 Jul; 37(29):6915-6925. PubMed ID: 28626014
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ryanodine receptor blockade reduces amyloid-β load and memory impairments in Tg2576 mouse model of Alzheimer disease.
    Oulès B; Del Prete D; Greco B; Zhang X; Lauritzen I; Sevalle J; Moreno S; Paterlini-Bréchot P; Trebak M; Checler F; Benfenati F; Chami M
    J Neurosci; 2012 Aug; 32(34):11820-34. PubMed ID: 22915123
    [TBL] [Abstract][Full Text] [Related]  

  • 14. APP-BACE1 Interaction and Intracellular Localization Regulate Aβ Production in iPSC-Derived Cortical Neurons.
    Roselli S; Satir TM; Camacho R; Fruhwürth S; Bergström P; Zetterberg H; Agholme L
    Cell Mol Neurobiol; 2023 Oct; 43(7):3653-3668. PubMed ID: 37355492
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential effects of familial Alzheimer's disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity.
    Schilling S; Pradhan A; Heesch A; Helbig A; Blennow K; Koch C; Bertgen L; Koo EH; Brinkmalm G; Zetterberg H; Kins S; Eggert S
    Acta Neuropathol Commun; 2023 Jun; 11(1):87. PubMed ID: 37259128
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PS1 Affects the Pathology of Alzheimer's Disease by Regulating BACE1 Distribution in the ER and BACE1 Maturation in the Golgi Apparatus.
    Li N; Qiu Y; Wang H; Zhao J; Qing H
    Int J Mol Sci; 2022 Dec; 23(24):. PubMed ID: 36555791
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cholesterol-lowering drugs reduce APP processing to Aβ by inducing APP dimerization.
    Langness VF; van der Kant R; Das U; Wang L; Chaves RDS; Goldstein LSB
    Mol Biol Cell; 2021 Feb; 32(3):247-259. PubMed ID: 33296223
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential regulation of amyloid precursor protein sorting with pathological mutations results in a distinct effect on amyloid-β production.
    Lin YC; Wang JY; Wang KC; Liao JY; Cheng IH
    J Neurochem; 2014 Nov; 131(4):407-12. PubMed ID: 25053581
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology.
    Sakae N; Liu CC; Shinohara M; Frisch-Daiello J; Ma L; Yamazaki Y; Tachibana M; Younkin L; Kurti A; Carrasquillo MM; Zou F; Sevlever D; Bisceglio G; Gan M; Fol R; Knight P; Wang M; Han X; Fryer JD; Fitzgerald ML; Ohyagi Y; Younkin SG; Bu G; Kanekiyo T
    J Neurosci; 2016 Mar; 36(13):3848-59. PubMed ID: 27030769
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synaptogenic effect of
    Zhou B; Lu JG; Siddu A; Wernig M; Südhof TC
    Sci Transl Med; 2022 Oct; 14(667):eabn9380. PubMed ID: 36260691
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.