199 related articles for article (PubMed ID: 35946936)
21. DRAM1 regulates autophagy and cell proliferation via inhibition of the phosphoinositide 3-kinase-Akt-mTOR-ribosomal protein S6 pathway.
Lu T; Zhu Z; Wu J; She H; Han R; Xu H; Qin ZH
Cell Commun Signal; 2019 Mar; 17(1):28. PubMed ID: 30902093
[TBL] [Abstract][Full Text] [Related]
22. HDAC6-G3BP2 promotes lysosomal-TSC2 and suppresses mTORC1 under ETV4 targeting-induced low-lactate stress in non-small cell lung cancer.
Liu B; Zhang J; Meng X; Xie SM; Liu F; Chen H; Yao D; Li M; Guo M; Shen H; Zhang X; Xing L
Oncogene; 2023 Apr; 42(15):1181-1195. PubMed ID: 36823378
[TBL] [Abstract][Full Text] [Related]
23. p53/TAp63 and AKT regulate mammalian target of rapamycin complex 1 (mTORC1) signaling through two independent parallel pathways in the presence of DNA damage.
Cam M; Bid HK; Xiao L; Zambetti GP; Houghton PJ; Cam H
J Biol Chem; 2014 Feb; 289(7):4083-94. PubMed ID: 24366874
[TBL] [Abstract][Full Text] [Related]
24. Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome.
Menon S; Dibble CC; Talbott G; Hoxhaj G; Valvezan AJ; Takahashi H; Cantley LC; Manning BD
Cell; 2014 Feb; 156(4):771-85. PubMed ID: 24529379
[TBL] [Abstract][Full Text] [Related]
25. Phosphorylation of TSC2 by PKC-δ reveals a novel signaling pathway that couples protein synthesis to mTORC1 activity.
Zhan J; Chitta RK; Harwood FC; Grosveld GC
Mol Cell Biochem; 2019 Jun; 456(1-2):123-134. PubMed ID: 30684133
[TBL] [Abstract][Full Text] [Related]
26. MicroRNA302-367-PI3K-PTEN-AKT-mTORC1 pathway promotes the development of cardiac hypertrophy through controlling autophagy.
Jin L; Zhou Y; Han L; Piao J
In Vitro Cell Dev Biol Anim; 2020 Feb; 56(2):112-119. PubMed ID: 31845077
[TBL] [Abstract][Full Text] [Related]
27. Heterozygous inactivation of tsc2 enhances tumorigenesis in p53 mutant zebrafish.
Kim SH; Kowalski ML; Carson RP; Bridges LR; Ess KC
Dis Model Mech; 2013 Jul; 6(4):925-33. PubMed ID: 23580196
[TBL] [Abstract][Full Text] [Related]
28. Resveratrol prevents rapamycin-induced upregulation of autophagy and selectively induces apoptosis in TSC2-deficient cells.
Alayev A; Sun Y; Snyder RB; Berger SM; Yu JJ; Holz MK
Cell Cycle; 2014; 13(3):371-82. PubMed ID: 24304514
[TBL] [Abstract][Full Text] [Related]
29. Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer.
Mirkheshti N; Park S; Jiang S; Cropper J; Werner SL; Song CS; Chatterjee B
Oncotarget; 2016 Sep; 7(38):62240-62254. PubMed ID: 27557496
[TBL] [Abstract][Full Text] [Related]
30. AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy.
Astle MV; Hannan KM; Ng PY; Lee RS; George AJ; Hsu AK; Haupt Y; Hannan RD; Pearson RB
Oncogene; 2012 Apr; 31(15):1949-62. PubMed ID: 21909130
[TBL] [Abstract][Full Text] [Related]
31. Cryptotanshinone activates AMPK-TSC2 axis leading to inhibition of mTORC1 signaling in cancer cells.
Chen W; Pan Y; Wang S; Liu Y; Chen G; Zhou L; Ni W; Wang A; Lu Y
BMC Cancer; 2017 Jan; 17(1):34. PubMed ID: 28061838
[TBL] [Abstract][Full Text] [Related]
32. p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb.
Agarwal S; Bell CM; Taylor SM; Moran RG
Mol Cancer Res; 2016 Jan; 14(1):66-77. PubMed ID: 26385560
[TBL] [Abstract][Full Text] [Related]
33. Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy.
Huang H; Kang R; Wang J; Luo G; Yang W; Zhao Z
Autophagy; 2013 Feb; 9(2):175-95. PubMed ID: 23169238
[TBL] [Abstract][Full Text] [Related]
34. Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway.
Zhang HH; Huang J; Düvel K; Boback B; Wu S; Squillace RM; Wu CL; Manning BD
PLoS One; 2009 Jul; 4(7):e6189. PubMed ID: 19593385
[TBL] [Abstract][Full Text] [Related]
35. Nuclear localization of the p17 protein of avian reovirus is correlated with autophagy induction and an increase in viral replication.
Li C; Wei H; Yu L; Duan S; Cheng J; Yan W; Zhang X; Wu Y
Arch Virol; 2015 Dec; 160(12):3001-10. PubMed ID: 26350773
[TBL] [Abstract][Full Text] [Related]
36. TGFβ acts through PDGFRβ to activate mTORC1 via the Akt/PRAS40 axis and causes glomerular mesangial cell hypertrophy and matrix protein expression.
Maity S; Das F; Kasinath BS; Ghosh-Choudhury N; Ghosh Choudhury G
J Biol Chem; 2020 Oct; 295(42):14262-14278. PubMed ID: 32732288
[TBL] [Abstract][Full Text] [Related]
37. Avian reovirus σA-modulated suppression of lactate dehydrogenase and upregulation of glutaminolysis and the mTOC1/eIF4E/HIF-1α pathway to enhance glycolysis and the TCA cycle for virus replication.
Chi PI; Huang WR; Chiu HC; Li JY; Nielsen BL; Liu HJ
Cell Microbiol; 2018 Dec; 20(12):e12946. PubMed ID: 30156372
[TBL] [Abstract][Full Text] [Related]
38. PDK4 protein promotes tumorigenesis through activation of cAMP-response element-binding protein (CREB)-Ras homolog enriched in brain (RHEB)-mTORC1 signaling cascade.
Liu Z; Chen X; Wang Y; Peng H; Wang Y; Jing Y; Zhang H
J Biol Chem; 2014 Oct; 289(43):29739-49. PubMed ID: 25164809
[TBL] [Abstract][Full Text] [Related]
39. Tumorigenesis in tuberous sclerosis complex is autophagy and p62/sequestosome 1 (SQSTM1)-dependent.
Parkhitko A; Myachina F; Morrison TA; Hindi KM; Auricchio N; Karbowniczek M; Wu JJ; Finkel T; Kwiatkowski DJ; Yu JJ; Henske EP
Proc Natl Acad Sci U S A; 2011 Jul; 108(30):12455-60. PubMed ID: 21746920
[TBL] [Abstract][Full Text] [Related]
40. The Gαh/phospholipase C-δ1 interaction promotes autophagosome degradation by activating the Akt/mTORC1 pathway in metastatic triple-negative breast cancer.
Lin HY; Kuei CH; Lee HH; Lin CH; Zheng JQ; Chiu HW; Chen CL; Lin YF
Aging (Albany NY); 2020 Jul; 12(13):13023-13037. PubMed ID: 32615541
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
