These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 35948006)

  • 1. Discovery of compounds that reactivate p53 mutants in vitro and in vivo.
    Durairaj G; Demir Ö; Lim B; Baronio R; Tifrea D; Hall LV; DeForest JC; Lauinger L; Jebril Fallatah MM; Yu C; Bae H; Lin DW; Kim JK; Salehi F; Jang C; Qiao F; Lathrop RH; Huang L; Edwards R; Rychnovsky S; Amaro RE; Kaiser P
    Cell Chem Biol; 2022 Sep; 29(9):1381-1395.e13. PubMed ID: 35948006
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reactivation of mutant p53 by a dietary-related compound phenethyl isothiocyanate inhibits tumor growth.
    Aggarwal M; Saxena R; Sinclair E; Fu Y; Jacobs A; Dyba M; Wang X; Cruz I; Berry D; Kallakury B; Mueller SC; Agostino SD; Blandino G; Avantaggiati ML; Chung FL
    Cell Death Differ; 2016 Oct; 23(10):1615-27. PubMed ID: 27258787
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reactivation of mutant p53 by capsaicin, the major constituent of peppers.
    Garufi A; Pistritto G; Cirone M; D'Orazi G
    J Exp Clin Cancer Res; 2016 Sep; 35(1):136. PubMed ID: 27599722
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Computational identification of a transiently open L1/S3 pocket for reactivation of mutant p53.
    Wassman CD; Baronio R; Demir Ö; Wallentine BD; Chen CK; Hall LV; Salehi F; Lin DW; Chung BP; Hatfield GW; Richard Chamberlin A; Luecke H; Lathrop RH; Kaiser P; Amaro RE
    Nat Commun; 2013; 4():1407. PubMed ID: 23360998
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations.
    Gomes AS; Ramos H; Gomes S; Loureiro JB; Soares J; Barcherini V; Monti P; Fronza G; Oliveira C; Domingues L; Bastos M; Dourado DFAR; Carvalho AL; Romão MJ; Pinheiro B; Marcelo F; Carvalho A; Santos MMM; Saraiva L
    Biochim Biophys Acta Gen Subj; 2020 Jan; 1864(1):129440. PubMed ID: 31536751
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reactivation of mutant p53: molecular mechanisms and therapeutic potential.
    Selivanova G; Wiman KG
    Oncogene; 2007 Apr; 26(15):2243-54. PubMed ID: 17401433
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p53 mutant-type in human prostate cancer cells determines the sensitivity to phenethyl isothiocyanate induced growth inhibition.
    Aggarwal M; Saxena R; Asif N; Sinclair E; Tan J; Cruz I; Berry D; Kallakury B; Pham Q; Wang TTY; Chung FL
    J Exp Clin Cancer Res; 2019 Jul; 38(1):307. PubMed ID: 31307507
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting Y220C mutated p53 by Foeniculum vulgare-derived phytochemicals as cancer therapeutics.
    Garg S; Singh J; Verma SR
    J Mol Model; 2023 Jan; 29(2):55. PubMed ID: 36700982
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer.
    Blanden AR; Yu X; Loh SN; Levine AJ; Carpizo DR
    Drug Discov Today; 2015 Nov; 20(11):1391-7. PubMed ID: 26205328
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutant p53 targeting by the low molecular weight compound STIMA-1.
    Zache N; Lambert JM; Rökaeus N; Shen J; Hainaut P; Bergman J; Wiman KG; Bykov VJ
    Mol Oncol; 2008 Jun; 2(1):70-80. PubMed ID: 19383329
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Thiosemicarbazones Functioning as Zinc Metallochaperones to Reactivate Mutant p53.
    Yu X; Blanden A; Tsang AT; Zaman S; Liu Y; Gilleran J; Bencivenga AF; Kimball SD; Loh SN; Carpizo DR
    Mol Pharmacol; 2017 Jun; 91(6):567-575. PubMed ID: 28320780
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A rare DNA contact mutation in cancer confers p53 gain-of-function and tumor cell survival via TNFAIP8 induction.
    Monteith JA; Mellert H; Sammons MA; Kuswanto LA; Sykes SM; Resnick-Silverman L; Manfredi JJ; Berger SL; McMahon SB
    Mol Oncol; 2016 Oct; 10(8):1207-20. PubMed ID: 27341992
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations.
    Suad O; Rozenberg H; Brosh R; Diskin-Posner Y; Kessler N; Shimon LJ; Frolow F; Liran A; Rotter V; Shakked Z
    J Mol Biol; 2009 Jan; 385(1):249-65. PubMed ID: 18996393
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rescue of the apoptotic-inducing function of mutant p53 by small molecule RITA.
    Zhao CY; Grinkevich VV; Nikulenkov F; Bao W; Selivanova G
    Cell Cycle; 2010 May; 9(9):1847-55. PubMed ID: 20436301
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Awakening the "guardian of genome": reactivation of mutant p53.
    Binayke A; Mishra S; Suman P; Das S; Chander H
    Cancer Chemother Pharmacol; 2019 Jan; 83(1):1-15. PubMed ID: 30324219
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting mutant p53 for efficient cancer therapy.
    Bykov VJN; Eriksson SE; Bianchi J; Wiman KG
    Nat Rev Cancer; 2018 Feb; 18(2):89-102. PubMed ID: 29242642
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Restoring p53-dependent tumor suppression.
    Wang W; Rastinejad F; El-Deiry WS
    Cancer Biol Ther; 2003; 2(4 Suppl 1):S55-63. PubMed ID: 14508081
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo.
    Xiong S; Chachad D; Zhang Y; Gencel-Augusto J; Sirito M; Pant V; Yang P; Sun C; Chau G; Qi Y; Su X; Whitley EM; El-Naggar AK; Lozano G
    Cancer Res; 2022 May; 82(10):1926-1936. PubMed ID: 35320355
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A fluorescent curcumin-based Zn(II)-complex reactivates mutant (R175H and R273H) p53 in cancer cells.
    Garufi A; Trisciuoglio D; Porru M; Leonetti C; Stoppacciaro A; D'Orazi V; Avantaggiati M; Crispini A; Pucci D; D'Orazi G
    J Exp Clin Cancer Res; 2013 Oct; 32(1):72. PubMed ID: 24220325
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insights into the Effect of the G245S Single Point Mutation on the Structure of p53 and the Binding of the Protein to DNA.
    Lepre MG; Omar SI; Grasso G; Morbiducci U; Deriu MA; Tuszynski JA
    Molecules; 2017 Aug; 22(8):. PubMed ID: 28813011
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.