145 related articles for article (PubMed ID: 35948768)
1. A conformational switch controlling the toxicity of the prion protein.
Frontzek K; Bardelli M; Senatore A; Henzi A; Reimann RR; Bedir S; Marino M; Hussain R; Jurt S; Meisl G; Pedotti M; Mazzola F; Siligardi G; Zerbe O; Losa M; Knowles T; Lakkaraju A; Zhu C; Schwarz P; Hornemann S; Holt MG; Simonelli L; Varani L; Aguzzi A
Nat Struct Mol Biol; 2022 Aug; 29(8):831-840. PubMed ID: 35948768
[TBL] [Abstract][Full Text] [Related]
2. Rapid ex vivo reverse genetics identifies the essential determinants of prion protein toxicity.
Reimann RR; Puzio M; Rosati A; Emmenegger M; Schneider BL; Valdés P; Huang D; Caflisch A; Aguzzi A
Brain Pathol; 2023 Mar; 33(2):e13130. PubMed ID: 36329611
[TBL] [Abstract][Full Text] [Related]
3. The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein.
Sonati T; Reimann RR; Falsig J; Baral PK; O'Connor T; Hornemann S; Yaganoglu S; Li B; Herrmann US; Wieland B; Swayampakula M; Rahman MH; Das D; Kav N; Riek R; Liberski PP; James MN; Aguzzi A
Nature; 2013 Sep; 501(7465):102-6. PubMed ID: 23903654
[TBL] [Abstract][Full Text] [Related]
4. Disassociation of β1-α1-β2 from the α2-α3 domain of prion protein (PrP) is a prerequisite for the conformational conversion of PrP
Chandrasekaran P; Santosh Kumar C; Rangachari K; Sekar K
Int J Biol Macromol; 2019 Sep; 136():368-376. PubMed ID: 31207327
[TBL] [Abstract][Full Text] [Related]
5. Virus Infection, Genetic Mutations, and Prion Infection in Prion Protein Conversion.
Hara H; Sakaguchi S
Int J Mol Sci; 2021 Nov; 22(22):. PubMed ID: 34830321
[TBL] [Abstract][Full Text] [Related]
6. Mutation-Dependent Refolding of Prion Protein Unveils Amyloidogenic-Related Structural Ramifications: Insights from Molecular Dynamics Simulations.
Palaniappan C; Narayanan RC; Sekar K
ACS Chem Neurosci; 2021 Aug; 12(15):2810-2819. PubMed ID: 34296847
[TBL] [Abstract][Full Text] [Related]
7. α2,3 linkage of sialic acid to a GPI anchor and an unpredicted GPI attachment site in human prion protein.
Kobayashi A; Hirata T; Nishikaze T; Ninomiya A; Maki Y; Takada Y; Kitamoto T; Kinoshita T
J Biol Chem; 2020 May; 295(22):7789-7798. PubMed ID: 32321762
[TBL] [Abstract][Full Text] [Related]
8. An inter-domain regulatory mechanism controls toxic activities of PrP
McDonald AJ; Wu B; Harris DA
Prion; 2017 Nov; 11(6):388-397. PubMed ID: 28960140
[TBL] [Abstract][Full Text] [Related]
9. Soluble polymorphic bank vole prion proteins induced by co-expression of quiescin sulfhydryl oxidase in E. coli and their aggregation behaviors.
Abskharon R; Dang J; Elfarash A; Wang Z; Shen P; Zou LS; Hassan S; Wang F; Fujioka H; Steyaert J; Mulaj M; Surewicz WK; Castilla J; Wohlkonig A; Zou WQ
Microb Cell Fact; 2017 Oct; 16(1):170. PubMed ID: 28978309
[TBL] [Abstract][Full Text] [Related]
10. Cellular prion protein offers neuroprotection in astrocytes submitted to amyloid β oligomer toxicity.
Marques CMS; Gomes RN; Pedron T; Batista BL; Cerchiaro G
Mol Cell Biochem; 2023 Aug; 478(8):1847-1865. PubMed ID: 36576715
[TBL] [Abstract][Full Text] [Related]
11. A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein.
Massignan T; Cimini S; Stincardini C; Cerovic M; Vanni I; Elezgarai SR; Moreno J; Stravalaci M; Negro A; Sangiovanni V; Restelli E; Riccardi G; Gobbi M; Castilla J; Borsello T; Nonno R; Biasini E
Sci Rep; 2016 Mar; 6():23180. PubMed ID: 26976106
[TBL] [Abstract][Full Text] [Related]
12. The first non-prion pathogen identified: neurotropic influenza virus.
Sakaguchi S; Hara H
Prion; 2022 Dec; 16(1):1-6. PubMed ID: 34978525
[TBL] [Abstract][Full Text] [Related]
13. Dimerization of the cellular prion protein inhibits propagation of scrapie prions.
Engelke AD; Gonsberg A; Thapa S; Jung S; Ulbrich S; Seidel R; Basu S; Multhaup G; Baier M; Engelhard M; Schätzl HM; Winklhofer KF; Tatzelt J
J Biol Chem; 2018 May; 293(21):8020-8031. PubMed ID: 29636413
[TBL] [Abstract][Full Text] [Related]
14. A proposed mechanism for the promotion of prion conversion involving a strictly conserved tyrosine residue in the β2-α2 loop of PrPC.
Kurt TD; Jiang L; Bett C; Eisenberg D; Sigurdson CJ
J Biol Chem; 2014 Apr; 289(15):10660-10667. PubMed ID: 24596090
[TBL] [Abstract][Full Text] [Related]
15. Pathogenic mutations within the hydrophobic domain of the prion protein lead to the formation of protease-sensitive prion species with increased lethality.
Coleman BM; Harrison CF; Guo B; Masters CL; Barnham KJ; Lawson VA; Hill AF
J Virol; 2014 Mar; 88(5):2690-703. PubMed ID: 24352465
[TBL] [Abstract][Full Text] [Related]
16. The N-Terminal Polybasic Region of Prion Protein Is Crucial in Prion Pathogenesis Independently of the Octapeptide Repeat Region.
Das NR; Miyata H; Hara H; Chida J; Uchiyama K; Masujin K; Watanabe H; Kondoh G; Sakaguchi S
Mol Neurobiol; 2020 Feb; 57(2):1203-1216. PubMed ID: 31707632
[TBL] [Abstract][Full Text] [Related]
17. Residue-specific mobility changes in soluble oligomers of the prion protein define regions involved in aggregation.
Glaves JP; Ladner-Keay CL; Bjorndahl TC; Wishart DS; Sykes BD
Biochim Biophys Acta Proteins Proteom; 2018 Sep; 1866(9):982-988. PubMed ID: 29935976
[TBL] [Abstract][Full Text] [Related]
18. A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity.
Bardelli M; Frontzek K; Simonelli L; Hornemann S; Pedotti M; Mazzola F; Carta M; Eckhardt V; D'Antuono R; Virgilio T; González SF; Aguzzi A; Varani L
PLoS Pathog; 2018 Oct; 14(10):e1007335. PubMed ID: 30273408
[TBL] [Abstract][Full Text] [Related]
19. Mouse prion protein (PrP) segment 100 to 104 regulates conversion of PrP(C) to PrP(Sc) in prion-infected neuroblastoma cells.
Hara H; Okemoto-Nakamura Y; Shinkai-Ouchi F; Hanada K; Yamakawa Y; Hagiwara K
J Virol; 2012 May; 86(10):5626-36. PubMed ID: 22398286
[TBL] [Abstract][Full Text] [Related]
20. Channel Activities of the Full-Length Prion and Truncated Proteins.
Wu J; Wang X; Lakkaraju A; Sternke-Hoffmann R; Qureshi BM; Aguzzi A; Luo J
ACS Chem Neurosci; 2024 Jan; 15(1):98-107. PubMed ID: 38096481
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
