139 related articles for article (PubMed ID: 35963427)
21. Prediction models for drug-induced hepatotoxicity by using weighted molecular fingerprints.
Kim E; Nam H
BMC Bioinformatics; 2017 May; 18(Suppl 7):227. PubMed ID: 28617228
[TBL] [Abstract][Full Text] [Related]
22. In vitro assessment of drug-induced liver steatosis based on human dermal stem cell-derived hepatic cells.
Rodrigues RM; Branson S; De Boe V; Sachinidis A; Rogiers V; De Kock J; Vanhaecke T
Arch Toxicol; 2016 Mar; 90(3):677-89. PubMed ID: 25716160
[TBL] [Abstract][Full Text] [Related]
23. A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity.
Sison-Young RL; Lauschke VM; Johann E; Alexandre E; Antherieu S; Aerts H; Gerets HHJ; Labbe G; Hoët D; Dorau M; Schofield CA; Lovatt CA; Holder JC; Stahl SH; Richert L; Kitteringham NR; Jones RP; Elmasry M; Weaver RJ; Hewitt PG; Ingelman-Sundberg M; Goldring CE; Park BK
Arch Toxicol; 2017 Mar; 91(3):1385-1400. PubMed ID: 27344343
[TBL] [Abstract][Full Text] [Related]
24. Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Sakatis MZ; Reese MJ; Harrell AW; Taylor MA; Baines IA; Chen L; Bloomer JC; Yang EY; Ellens HM; Ambroso JL; Lovatt CA; Ayrton AD; Clarke SE
Chem Res Toxicol; 2012 Oct; 25(10):2067-82. PubMed ID: 22931300
[TBL] [Abstract][Full Text] [Related]
25. A blinded in vitro analysis of the intrinsic immunogenicity of hepatotoxic drugs: implications for preclinical risk assessment.
Ogese MO; Lister A; Farrell L; Gardner J; Kafu L; Ali SE; Gibson A; Hillegas A; Meng X; Pirmohamed M; Williams GS; Sakatis MZ; Naisbitt DJ
Toxicol Sci; 2023 Dec; 197(1):38-52. PubMed ID: 37788119
[TBL] [Abstract][Full Text] [Related]
26. Advantageous use of HepaRG cells for the screening and mechanistic study of drug-induced steatosis.
Tolosa L; Gómez-Lechón MJ; Jiménez N; Hervás D; Jover R; Donato MT
Toxicol Appl Pharmacol; 2016 Jul; 302():1-9. PubMed ID: 27089845
[TBL] [Abstract][Full Text] [Related]
27. In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries.
Utkarsh D; Loretz C; Li AP
Chem Biol Interact; 2016 Aug; 255():12-22. PubMed ID: 26718876
[TBL] [Abstract][Full Text] [Related]
28. Comparing Machine Learning Algorithms for Predicting Drug-Induced Liver Injury (DILI).
Minerali E; Foil DH; Zorn KM; Lane TR; Ekins S
Mol Pharm; 2020 Jul; 17(7):2628-2637. PubMed ID: 32422053
[TBL] [Abstract][Full Text] [Related]
29. Cell-based assay using glutathione-depleted HepaRG and HepG2 human liver cells for predicting drug-induced liver injury.
Xu J; Oda S; Yokoi T
Toxicol In Vitro; 2018 Apr; 48():286-301. PubMed ID: 29407385
[TBL] [Abstract][Full Text] [Related]
30. Prediction of liver injury induced by chemicals in human with a multiparametric assay on isolated mouse liver mitochondria.
Porceddu M; Buron N; Roussel C; Labbe G; Fromenty B; Borgne-Sanchez A
Toxicol Sci; 2012 Oct; 129(2):332-45. PubMed ID: 22987451
[TBL] [Abstract][Full Text] [Related]
31. Long-enduring primary hepatocyte-based co-cultures improve prediction of hepatotoxicity.
Novik EI; Dwyer J; Morelli JK; Parekh A; Cho C; Pludwinski E; Shrirao A; Freedman RM; MacDonald JS; Jayyosi Z
Toxicol Appl Pharmacol; 2017 Dec; 336():20-30. PubMed ID: 28942002
[TBL] [Abstract][Full Text] [Related]
32. Cytotoxicity evaluation using cryopreserved primary human hepatocytes in various culture formats.
Richert L; Baze A; Parmentier C; Gerets HHJ; Sison-Young R; Dorau M; Lovatt C; Czich A; Goldring C; Park BK; Juhila S; Foster AJ; Williams DP
Toxicol Lett; 2016 Sep; 258():207-215. PubMed ID: 27363785
[TBL] [Abstract][Full Text] [Related]
33. Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Liu Z; Shi Q; Ding D; Kelly R; Fang H; Tong W
PLoS Comput Biol; 2011 Dec; 7(12):e1002310. PubMed ID: 22194678
[TBL] [Abstract][Full Text] [Related]
34. Current challenges and controversies in drug-induced liver injury.
Corsini A; Ganey P; Ju C; Kaplowitz N; Pessayre D; Roth R; Watkins PB; Albassam M; Liu B; Stancic S; Suter L; Bortolini M
Drug Saf; 2012 Dec; 35(12):1099-117. PubMed ID: 23137150
[TBL] [Abstract][Full Text] [Related]
35. Tetracycline-induced steatosis in primary canine hepatocyte cultures.
Amacher DE; Martin BA
Fundam Appl Toxicol; 1997 Dec; 40(2):256-63. PubMed ID: 9441722
[TBL] [Abstract][Full Text] [Related]
36. Influence of bile acids on the cytotoxicity of chemicals in cultivated human hepatocytes.
Brecklinghaus T; Albrecht W; Kappenberg F; Duda J; Zhang M; Gardner I; Marchan R; Ghallab A; Demirci Turgunbayer Ö; Rahnenführer J; Hengstler JG
Toxicol In Vitro; 2022 Jun; 81():105344. PubMed ID: 35263627
[TBL] [Abstract][Full Text] [Related]
37. Morphological and Functional Characterization and Assessment of iPSC-Derived Hepatocytes for In Vitro Toxicity Testing.
Lu J; Einhorn S; Venkatarangan L; Miller M; Mann DA; Watkins PB; LeCluyse E
Toxicol Sci; 2015 Sep; 147(1):39-54. PubMed ID: 26092927
[TBL] [Abstract][Full Text] [Related]
38. Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro.
Novac O; Silva R; Young LM; Lachani K; Hughes D; Kostrzewski T
J Vis Exp; 2022 Jan; (179):. PubMed ID: 35156664
[TBL] [Abstract][Full Text] [Related]
39. Bioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In Vitro.
Nguyen DG; Funk J; Robbins JB; Crogan-Grundy C; Presnell SC; Singer T; Roth AB
PLoS One; 2016; 11(7):e0158674. PubMed ID: 27387377
[TBL] [Abstract][Full Text] [Related]
40. Prediction of drug induced liver injury using molecular and biological descriptors.
Muller C; Pekthong D; Alexandre E; Marcou G; Horvath D; Richert L; Varnek A
Comb Chem High Throughput Screen; 2015; 18(3):315-22. PubMed ID: 25747442
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
