164 related articles for article (PubMed ID: 35966593)
1. MAP4K3/GLK inhibits Treg differentiation by direct phosphorylating IKKβ and inducing IKKβ-mediated FoxO1 nuclear export and Foxp3 downregulation.
Chi JN; Yang JY; Hsueh CH; Tsai CY; Chuang HC; Tan TH
Theranostics; 2022; 12(13):5744-5760. PubMed ID: 35966593
[No Abstract] [Full Text] [Related]
2. GLK-IKKβ signaling induces dimerization and translocation of the AhR-RORγt complex in IL-17A induction and autoimmune disease.
Chuang HC; Tsai CY; Hsueh CH; Tan TH
Sci Adv; 2018 Sep; 4(9):eaat5401. PubMed ID: 30214937
[TBL] [Abstract][Full Text] [Related]
3. MAP4K3/GLK in autoimmune disease, cancer and aging.
Chuang HC; Tan TH
J Biomed Sci; 2019 Oct; 26(1):82. PubMed ID: 31640697
[TBL] [Abstract][Full Text] [Related]
4. Mst1/Mst2 regulate development and function of regulatory T cells through modulation of Foxo1/Foxo3 stability in autoimmune disease.
Du X; Shi H; Li J; Dong Y; Liang J; Ye J; Kong S; Zhang S; Zhong T; Yuan Z; Xu T; Zhuang Y; Zheng B; Geng JG; Tao W
J Immunol; 2014 Feb; 192(4):1525-35. PubMed ID: 24453252
[TBL] [Abstract][Full Text] [Related]
5. AhR-ROR-γt complex is a therapeutic target for MAP4K3/GLK
Chuang HC; Chen YM; Chen MH; Hung WT; Yang HY; Tseng YH; Tan TH
FASEB J; 2019 Oct; 33(10):11469-11480. PubMed ID: 31318609
[TBL] [Abstract][Full Text] [Related]
6. Graded Foxo1 activity in Treg cells differentiates tumour immunity from spontaneous autoimmunity.
Luo CT; Liao W; Dadi S; Toure A; Li MO
Nature; 2016 Jan; 529(7587):532-6. PubMed ID: 26789248
[TBL] [Abstract][Full Text] [Related]
7. MAP4K Family Kinases in Immunity and Inflammation.
Chuang HC; Wang X; Tan TH
Adv Immunol; 2016; 129():277-314. PubMed ID: 26791862
[TBL] [Abstract][Full Text] [Related]
8. The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells.
Chuang HC; Lan JL; Chen DY; Yang CY; Chen YM; Li JP; Huang CY; Liu PE; Wang X; Tan TH
Nat Immunol; 2011 Oct; 12(11):1113-8. PubMed ID: 21983831
[TBL] [Abstract][Full Text] [Related]
9. Investigating small molecules to inhibit germinal center kinase-like kinase (GLK/MAP4K3) upstream of PKCθ phosphorylation: Potential therapy to modulate T cell dependent immunity.
May-Dracka TL; Arduini R; Bertolotti-Ciarlet A; Bhisetti G; Brickelmaier M; Cahir-McFarland E; Enyedy I; Fontenot JD; Hesson T; Little K; Lyssikatos J; Marcotte D; McKee T; Murugan P; Patterson T; Peng H; Rushe M; Silvian L; Spilker K; Wu P; Xin Z; Burkly LC
Bioorg Med Chem Lett; 2018 Jun; 28(10):1964-1971. PubMed ID: 29636220
[TBL] [Abstract][Full Text] [Related]
10. SRC1 promotes Th17 differentiation by overriding Foxp3 suppression to stimulate RORγt activity in a PKC-θ-dependent manner.
Sen S; Wang F; Zhang J; He Z; Ma J; Gwack Y; Xu J; Sun Z
Proc Natl Acad Sci U S A; 2018 Jan; 115(3):E458-E467. PubMed ID: 29282318
[TBL] [Abstract][Full Text] [Related]
11. Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression.
Kim SJ; Winter K; Nian C; Tsuneoka M; Koda Y; McIntosh CH
J Biol Chem; 2005 Jun; 280(23):22297-307. PubMed ID: 15817464
[TBL] [Abstract][Full Text] [Related]
12. Ablation of peroxiredoxin II attenuates experimental colitis by increasing FoxO1-induced Foxp3+ regulatory T cells.
Won HY; Jang EJ; Lee K; Oh S; Kim HK; Woo HA; Kang SW; Yu DY; Rhee SG; Hwang ES
J Immunol; 2013 Oct; 191(8):4029-37. PubMed ID: 24048895
[TBL] [Abstract][Full Text] [Related]
13. CK2 Controls Th17 and Regulatory T Cell Differentiation Through Inhibition of FoxO1.
Gibson SA; Yang W; Yan Z; Qin H; Benveniste EN
J Immunol; 2018 Jul; 201(2):383-392. PubMed ID: 29891553
[TBL] [Abstract][Full Text] [Related]
14. Nuclear forkhead box O1 controls and integrates key signaling pathways in hepatocytes.
Naïmi M; Gautier N; Chaussade C; Valverde AM; Accili D; Van Obberghen E
Endocrinology; 2007 May; 148(5):2424-34. PubMed ID: 17303659
[TBL] [Abstract][Full Text] [Related]
15. MAP4K3/GLK Promotes Lung Cancer Metastasis by Phosphorylating and Activating IQGAP1.
Chuang HC; Chang CC; Teng CF; Hsueh CH; Chiu LL; Hsu PM; Lee MC; Hsu CP; Chen YR; Liu YC; Lyu PC; Tan TH
Cancer Res; 2019 Oct; 79(19):4978-4993. PubMed ID: 31431460
[TBL] [Abstract][Full Text] [Related]
16. Forkhead-box transcription factor 1 affects the apoptosis of natural regulatory T cells by controlling Aven expression.
Cai Z; Liu H; Wu X
BMC Immunol; 2017 Mar; 18(1):16. PubMed ID: 28283017
[TBL] [Abstract][Full Text] [Related]
17. Increased CD4
Ma YH; Zhang J; Chen X; Xie YF; Pang YH; Liu XJ
World J Gastroenterol; 2016 Nov; 22(42):9356-9367. PubMed ID: 27895423
[TBL] [Abstract][Full Text] [Related]
18. A Stk4-Foxp3-NF-κB p65 transcriptional complex promotes T
Cui Y; Benamar M; Schmitz-Abe K; Poondi-Krishnan V; Chen Q; Jugder BE; Fatou B; Fong J; Zhong Y; Mehta S; Buyanbat A; Eklioglu BS; Karabiber E; Baris S; Kiykim A; Keles S; Stephen-Victor E; Angelini C; Charbonnier LM; Chatila TA
Sci Immunol; 2022 Sep; 7(75):eabl8357. PubMed ID: 36149942
[TBL] [Abstract][Full Text] [Related]
19. Protein kinase Cδ regulates nuclear export of FOXO1 through phosphorylation of the chaperone 14-3-3ζ.
Gerst F; Kaiser G; Panse M; Sartorius T; Pujol A; Hennige AM; Machicao F; Lammers R; Bosch F; Häring HU; Ullrich S
Diabetologia; 2015 Dec; 58(12):2819-31. PubMed ID: 26363783
[TBL] [Abstract][Full Text] [Related]
20. Ex vivo modulation of the Foxo1 phosphorylation state does not lead to dysfunction of T regulatory cells.
Penberthy KK; Buckley MW; Arandjelovic S; Ravichandran K
PLoS One; 2017; 12(3):e0173386. PubMed ID: 28267764
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
