These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 35970394)

  • 1. Disulfide-crosslink analysis of the ubiquitin ligase Hrd1 complex during endoplasmic reticulum-associated protein degradation.
    Pisa R; Rapoport TA
    J Biol Chem; 2022 Sep; 298(9):102373. PubMed ID: 35970394
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.
    Wu X; Siggel M; Ovchinnikov S; Mi W; Svetlov V; Nudler E; Liao M; Hummer G; Rapoport TA
    Science; 2020 Apr; 368(6489):. PubMed ID: 32327568
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cycles of autoubiquitination and deubiquitination regulate the ERAD ubiquitin ligase Hrd1.
    Peterson BG; Glaser ML; Rapoport TA; Baldridge RD
    Elife; 2019 Nov; 8():. PubMed ID: 31713515
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.
    Schoebel S; Mi W; Stein A; Ovchinnikov S; Pavlovicz R; DiMaio F; Baker D; Chambers MG; Su H; Li D; Rapoport TA; Liao M
    Nature; 2017 Aug; 548(7667):352-355. PubMed ID: 28682307
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Direct and essential function for Hrd3 in ER-associated degradation.
    Vashistha N; Neal SE; Singh A; Carroll SM; Hampton RY
    Proc Natl Acad Sci U S A; 2016 May; 113(21):5934-9. PubMed ID: 27170191
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Autoubiquitination of the Hrd1 Ligase Triggers Protein Retrotranslocation in ERAD.
    Baldridge RD; Rapoport TA
    Cell; 2016 Jul; 166(2):394-407. PubMed ID: 27321670
    [TBL] [Abstract][Full Text] [Related]  

  • 7. N-terminal acetylation of the yeast Derlin Der1 is essential for Hrd1 ubiquitin-ligase activity toward luminal ER substrates.
    Zattas D; Adle DJ; Rubenstein EM; Hochstrasser M
    Mol Biol Cell; 2013 Apr; 24(7):890-900. PubMed ID: 23363603
    [TBL] [Abstract][Full Text] [Related]  

  • 8. gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum.
    Zhang T; Xu Y; Liu Y; Ye Y
    Mol Biol Cell; 2015 Dec; 26(24):4438-50. PubMed ID: 26424800
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Deep mutational scanning highlights a role for cytosolic regions in Hrd1 function.
    Peterson BG; Hwang J; Russ JE; Schroeder JW; Freddolino PL; Baldridge RD
    Cell Rep; 2023 Nov; 42(11):113451. PubMed ID: 37980570
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates.
    Iida Y; Fujimori T; Okawa K; Nagata K; Wada I; Hosokawa N
    J Biol Chem; 2011 May; 286(19):16929-39. PubMed ID: 21454652
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of HERP and a HERP-related protein in HRD1-dependent protein degradation at the endoplasmic reticulum.
    Huang CH; Chu YR; Ye Y; Chen X
    J Biol Chem; 2014 Feb; 289(7):4444-54. PubMed ID: 24366871
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane.
    Mehnert M; Sommer T; Jarosch E
    Nat Cell Biol; 2014 Jan; 16(1):77-86. PubMed ID: 24292014
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A stalled retrotranslocation complex reveals physical linkage between substrate recognition and proteasomal degradation during ER-associated degradation.
    Nakatsukasa K; Brodsky JL; Kamura T
    Mol Biol Cell; 2013 Jun; 24(11):1765-75, S1-8. PubMed ID: 23536702
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A positive genetic selection for transmembrane domain mutations in HRD1 underscores the importance of Hrd1 complex integrity during ERAD.
    Nakatsukasa K; Wigge S; Takano Y; Kawarasaki T; Kamura T; Brodsky JL
    Curr Genet; 2022 Apr; 68(2):227-242. PubMed ID: 35041076
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p.
    Carvalho P; Stanley AM; Rapoport TA
    Cell; 2010 Nov; 143(4):579-91. PubMed ID: 21074049
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ER-associated Protein Degradation at Atomic Resolution.
    Eldeeb MA; Fahlman RP; Michalak M
    Trends Biochem Sci; 2020 Sep; 45(9):723-725. PubMed ID: 32616332
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Association of the SEL1L protein transmembrane domain with HRD1 ubiquitin ligase regulates ERAD-L.
    Hosokawa N; Wada I
    FEBS J; 2016 Jan; 283(1):157-72. PubMed ID: 26471130
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Direct observation of autoubiquitination for an integral membrane ubiquitin ligase in ERAD.
    Moochickal Assainar B; Ragunathan K; Baldridge RD
    Nat Commun; 2024 Feb; 15(1):1340. PubMed ID: 38351109
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Misfolded proteins induce aggregation of the lectin Yos9.
    Smith MH; Rodriguez EH; Weissman JS
    J Biol Chem; 2014 Sep; 289(37):25670-7. PubMed ID: 25086047
    [TBL] [Abstract][Full Text] [Related]  

  • 20. USP19-Mediated Deubiquitination Facilitates the Stabilization of HRD1 Ubiquitin Ligase.
    Harada K; Kato M; Nakamura N
    Int J Mol Sci; 2016 Nov; 17(11):. PubMed ID: 27827840
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.