BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

267 related articles for article (PubMed ID: 35972384)

  • 1. Targeting DNA Repair with Combined Inhibition of NHEJ and MMEJ Induces Synthetic Lethality in TP53-Mutant Cancers.
    Patterson-Fortin J; Bose A; Tsai WC; Grochala C; Nguyen H; Zhou J; Parmar K; Lazaro JB; Liu J; McQueen K; Shapiro GI; Kozono D; D'Andrea AD
    Cancer Res; 2022 Oct; 82(20):3815-3829. PubMed ID: 35972384
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Polymerase θ Coordinates Multiple Intrinsic Enzymatic Activities during DNA Repair.
    Zahn KE; Jensen RB
    Genes (Basel); 2021 Aug; 12(9):. PubMed ID: 34573292
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting Polymerase Theta (POLθ) for Cancer Therapy.
    Patterson-Fortin J; D'Andrea AD
    Cancer Treat Res; 2023; 186():285-298. PubMed ID: 37978141
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Contribution of Microhomology to Genome Instability: Connection between DNA Repair and Replication Stress.
    Jiang Y
    Int J Mol Sci; 2022 Oct; 23(21):. PubMed ID: 36361724
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA-PK inhibitor peposertib enhances p53-dependent cytotoxicity of DNA double-strand break inducing therapy in acute leukemia.
    Haines E; Nishida Y; Carr MI; Montoya RH; Ostermann LB; Zhang W; Zenke FT; Blaukat A; Andreeff M; Vassilev LT
    Sci Rep; 2021 Jun; 11(1):12148. PubMed ID: 34108527
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA polymerase θ (POLQ) is important for repair of DNA double-strand breaks caused by fork collapse.
    Wang Z; Song Y; Li S; Kurian S; Xiang R; Chiba T; Wu X
    J Biol Chem; 2019 Mar; 294(11):3909-3919. PubMed ID: 30655289
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair.
    Ceccaldi R; Liu JC; Amunugama R; Hajdu I; Primack B; Petalcorin MI; O'Connor KW; Konstantinopoulos PA; Elledge SJ; Boulton SJ; Yusufzai T; D'Andrea AD
    Nature; 2015 Feb; 518(7538):258-62. PubMed ID: 25642963
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Polλ promotes microhomology-mediated end-joining.
    Chandramouly G; Jamsen J; Borisonnik N; Tyagi M; Calbert ML; Tredinnick T; Ozdemir AY; Kent T; Demidova EV; Arora S; Wilson SH; Pomerantz RT
    Nat Struct Mol Biol; 2023 Jan; 30(1):107-114. PubMed ID: 36536104
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Polθ Inhibition: An Anticancer Therapy for HR-Deficient Tumours.
    Barszczewska-Pietraszek G; Drzewiecka M; Czarny P; Skorski T; Śliwiński T
    Int J Mol Sci; 2022 Dec; 24(1):. PubMed ID: 36613762
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Polθ promotes the repair of 5'-DNA-protein crosslinks by microhomology-mediated end-joining.
    Chandramouly G; Liao S; Rusanov T; Borisonnik N; Calbert ML; Kent T; Sullivan-Reed K; Vekariya U; Kashkina E; Skorski T; Yan H; Pomerantz RT
    Cell Rep; 2021 Mar; 34(10):108820. PubMed ID: 33691100
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA polymerase θ (POLQ), double-strand break repair, and cancer.
    Wood RD; Doublié S
    DNA Repair (Amst); 2016 Aug; 44():22-32. PubMed ID: 27264557
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Efficient biallelic knock-in in mouse embryonic stem cells by in vivo-linearization of donor and transient inhibition of DNA polymerase θ/DNA-PK.
    Arai D; Nakao Y
    Sci Rep; 2021 Sep; 11(1):18132. PubMed ID: 34518609
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RHINO directs MMEJ to repair DNA breaks in mitosis.
    Brambati A; Sacco O; Porcella S; Heyza J; Kareh M; Schmidt JC; Sfeir A
    Science; 2023 Aug; 381(6658):653-660. PubMed ID: 37440612
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthetic Lethality Targeting Polθ.
    Drzewiecka M; Barszczewska-Pietraszek G; Czarny P; Skorski T; Śliwiński T
    Genes (Basel); 2022 Jun; 13(6):. PubMed ID: 35741863
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ.
    Kent T; Chandramouly G; McDevitt SM; Ozdemir AY; Pomerantz RT
    Nat Struct Mol Biol; 2015 Mar; 22(3):230-7. PubMed ID: 25643323
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A Phase 1 Study of the DNA-PK Inhibitor Peposertib in Combination With Radiation Therapy With or Without Cisplatin in Patients With Advanced Head and Neck Tumors.
    Samuels M; Falkenius J; Bar-Ad V; Dunst J; van Triest B; Yachnin J; Rodriguez-Gutierrez A; Kuipers M; You X; Sarholz B; Locatelli G; Becker A; Troost EGC
    Int J Radiat Oncol Biol Phys; 2024 Mar; 118(3):743-756. PubMed ID: 37751793
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA polymerase theta (Polθ) - an error-prone polymerase necessary for genome stability.
    Brambati A; Barry RM; Sfeir A
    Curr Opin Genet Dev; 2020 Feb; 60():119-126. PubMed ID: 32302896
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining.
    Fleury H; MacEachern MK; Stiefel CM; Anand R; Sempeck C; Nebenfuehr B; Maurer-Alcalá K; Ball K; Proctor B; Belan O; Taylor E; Ortega R; Dodd B; Weatherly L; Dansoko D; Leung JW; Boulton SJ; Arnoult N
    Mol Cell; 2023 May; 83(9):1429-1445.e8. PubMed ID: 37044098
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Assays for DNA double-strand break repair by microhomology-based end-joining repair mechanisms.
    Kostyrko K; Mermod N
    Nucleic Acids Res; 2016 Apr; 44(6):e56. PubMed ID: 26657630
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models.
    Zenke FT; Zimmermann A; Sirrenberg C; Dahmen H; Kirkin V; Pehl U; Grombacher T; Wilm C; Fuchss T; Amendt C; Vassilev LT; Blaukat A
    Mol Cancer Ther; 2020 May; 19(5):1091-1101. PubMed ID: 32220971
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.