BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 35973051)

  • 1. Hydroxamic Acid-Modified Peptide Library Provides Insights into the Molecular Basis for the Substrate Selectivity of HDAC Corepressor Complexes.
    Archibald LJ; Brown EA; Millard CJ; Watson PJ; Robertson NS; Wang S; Schwabe JWR; Jamieson AG
    ACS Chem Biol; 2022 Sep; 17(9):2572-2582. PubMed ID: 35973051
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Probing the structure-activity relationship of endogenous histone deacetylase complexes with immobilized peptide-inhibitors.
    Sindlinger J; Bierlmeier J; Geiger LC; Kramer K; Finkemeier I; Schwarzer D
    J Pept Sci; 2016 May; 22(5):352-9. PubMed ID: 27071932
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Kinetics and comparative reactivity of human class I and class IIb histone deacetylases.
    Schultz BE; Misialek S; Wu J; Tang J; Conn MT; Tahilramani R; Wong L
    Biochemistry; 2004 Aug; 43(34):11083-91. PubMed ID: 15323567
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chemical Versatility in Catalysis and Inhibition of the Class IIb Histone Deacetylases.
    Christianson DW
    Acc Chem Res; 2024 Apr; 57(8):1135-1148. PubMed ID: 38530703
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Peptide-Based 2-Aminophenylamide Probes for Targeting Endogenous Class I Histone Deacetylase Complexes.
    Seidel J; Meisinger T; Sindlinger J; Pieloch P; Finkemeier I; Schwarzer D
    Chembiochem; 2019 Dec; 20(24):3001-3005. PubMed ID: 31270913
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The structural requirements of histone deacetylase inhibitors: C4-modified SAHA analogs display dual HDAC6/HDAC8 selectivity.
    Negmeldin AT; Knoff JR; Pflum MKH
    Eur J Med Chem; 2018 Jan; 143():1790-1806. PubMed ID: 29150330
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HDAC8 substrate selectivity is determined by long- and short-range interactions leading to enhanced reactivity for full-length histone substrates compared with peptides.
    Castañeda CA; Wolfson NA; Leng KR; Kuo YM; Andrews AJ; Fierke CA
    J Biol Chem; 2017 Dec; 292(52):21568-21577. PubMed ID: 29109148
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PROTAC-mediated degradation of class I histone deacetylase enzymes in corepressor complexes.
    Smalley JP; Adams GE; Millard CJ; Song Y; Norris JKS; Schwabe JWR; Cowley SM; Hodgkinson JT
    Chem Commun (Camb); 2020 Apr; 56(32):4476-4479. PubMed ID: 32201871
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Members of the histone deacetylase superfamily differ in substrate specificity towards small synthetic substrates.
    Riester D; Wegener D; Hildmann C; Schwienhorst A
    Biochem Biophys Res Commun; 2004 Nov; 324(3):1116-23. PubMed ID: 15485670
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Diverse nucleosome Site-Selectivity among histone deacetylase complexes.
    Wang ZA; Millard CJ; Lin CL; Gurnett JE; Wu M; Lee K; Fairall L; Schwabe JW; Cole PA
    Elife; 2020 Jun; 9():. PubMed ID: 32501215
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Diarylcyclopropane hydroxamic acid inhibitors of histone deacetylase 4 designed by combinatorial approach and QM/MM calculations.
    Kollar J; Frecer V
    J Mol Graph Model; 2018 Oct; 85():97-110. PubMed ID: 30145395
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development and characterization of a CNS-penetrant benzhydryl hydroxamic acid class IIa histone deacetylase inhibitor.
    Luckhurst CA; Aziz O; Beaumont V; Bürli RW; Breccia P; Maillard MC; Haughan AF; Lamers M; Leonard P; Matthews KL; Raphy G; Stott AJ; Munoz-Sanjuan I; Thomas B; Wall M; Wishart G; Yates D; Dominguez C
    Bioorg Med Chem Lett; 2019 Jan; 29(1):83-88. PubMed ID: 30463802
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and synthesis of novel histone deacetylase inhibitor derived from nuclear localization signal peptide.
    Canzoneri JC; Chen PC; Oyelere AK
    Bioorg Med Chem Lett; 2009 Dec; 19(23):6588-90. PubMed ID: 19854643
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vitro targeting reveals intrinsic histone tail specificity of the Sin3/histone deacetylase and N-CoR/SMRT corepressor complexes.
    Vermeulen M; Carrozza MJ; Lasonder E; Workman JL; Logie C; Stunnenberg HG
    Mol Cell Biol; 2004 Mar; 24(6):2364-72. PubMed ID: 14993276
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The structural requirements of histone deacetylase inhibitors: SAHA analogs modified at the C5 position display dual HDAC6/8 selectivity.
    Negmeldin AT; Pflum MKH
    Bioorg Med Chem Lett; 2017 Aug; 27(15):3254-3258. PubMed ID: 28648461
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of 'linkerless' hydroxamic acid inhibitor-HDAC8 complex confirms the formation of an isoform-specific subpocket.
    Tabackman AA; Frankson R; Marsan ES; Perry K; Cole KE
    J Struct Biol; 2016 Sep; 195(3):373-378. PubMed ID: 27374062
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Histone deacetylase 1/mSin3A disrupts gamma interferon-induced CIITA function and major histocompatibility complex class II enhanceosome formation.
    Zika E; Greer SF; Zhu XS; Ting JP
    Mol Cell Biol; 2003 May; 23(9):3091-102. PubMed ID: 12697811
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphorus containing analogues of SAHA as inhibitors of HDACs.
    Pun MD; Wu HH; Olatunji FP; Kesic BN; Peters JW; Berkman CE
    J Enzyme Inhib Med Chem; 2022 Dec; 37(1):1315-1319. PubMed ID: 35514164
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The structural requirements of histone deacetylase inhibitors: suberoylanilide hydroxamic acid analogs modified at the C6 position.
    Choi SE; Pflum MK
    Bioorg Med Chem Lett; 2012 Dec; 22(23):7084-6. PubMed ID: 23089527
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Histone Deacetylase 11 Is an ε-N-Myristoyllysine Hydrolase.
    Moreno-Yruela C; Galleano I; Madsen AS; Olsen CA
    Cell Chem Biol; 2018 Jul; 25(7):849-856.e8. PubMed ID: 29731425
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.