BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

4800 related articles for article (PubMed ID: 3597524)

  • 1. Increased cytotoxicity of 1-(2-chloroethyl)-1-nitroso-3(4-methyl)-cyclohexylurea by pretreatment with O6-methylguanine in resistant but not in sensitive human melanoma cells.
    Dempke W; Nehls P; Wandl U; Soll D; Schmidt CG; Osieka R
    J Cancer Res Clin Oncol; 1987; 113(4):387-91. PubMed ID: 3597524
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modulation of mammalian O6-alkylguanine-DNA alkyltransferase in vivo by O6-benzylguanine and its effect on the sensitivity of a human glioma tumor to 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea.
    Dolan ME; Stine L; Mitchell RB; Moschel RC; Pegg AE
    Cancer Commun; 1990; 2(11):371-7. PubMed ID: 2242301
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enhancement of ACNU cytotoxicity by pretreatment with O6-methylguanine in ACNU-resistant brain tumors.
    Mineura K; Izumi I; Watanabe K; Kowada M
    J Neurooncol; 1994; 19(1):51-9. PubMed ID: 7815104
    [TBL] [Abstract][Full Text] [Related]  

  • 4. O6-Alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea.
    Brent TP; Houghton PJ; Houghton JA
    Proc Natl Acad Sci U S A; 1985 May; 82(9):2985-9. PubMed ID: 3857628
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA damage induced by a new 2-chloroethyl nitrosourea on malignant melanoma cells.
    Godeneche D; Rapp M; Thierry A; Laval F; Madelmont JC; Chollet P; Veyre A
    Cancer Res; 1990 Sep; 50(18):5898-903. PubMed ID: 2393861
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of O6-methylguanine on DNA interstrand cross-link formation by chloroethylnitrosoureas and 2-chloroethyl(methylsulfonyl)methanesulfonate.
    Dolan ME; Pegg AE; Hora NK; Erickson LC
    Cancer Res; 1988 Jul; 48(13):3603-6. PubMed ID: 2837318
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Potential of O6-methylguanine or O6-benzylguanine in the enhancement of chloroethylnitrosourea cytotoxicity on brain tumours.
    Mineura K; Izumi I; Watanabe K; Kowada M; Kohda K; Ikenaga M
    Acta Neurochir (Wien); 1994; 128(1-4):13-20. PubMed ID: 7847129
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhancement by O6-benzyl-N-acetylguanosine derivatives of chloroethylnitrosourea antitumor action in chloroethylnitrosourea-resistant human malignant melanocytes.
    Cussac C; Rapp M; Mounetou E; Madelmont JC; Maurizis JC; Godeneche D; Dupuy JM; Sauzieres J; Baudry JP; Veyre A
    J Pharmacol Exp Ther; 1994 Dec; 271(3):1353-8. PubMed ID: 7996446
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enhancement of semustine-induced cytotoxicity by chlorpromazine and caffeine in a human melanoma xenograft.
    Osieka R; Glatte P; Pannenbäcker R; Schmidt CG
    Cancer Treat Rep; 1986 Oct; 70(10):1167-71. PubMed ID: 3756939
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cytotoxicity, DNA damage, and apoptosis induced by new fotemustine analogs on human melanoma cells in relation to O6-methylguanine DNA-methyltransferase expression.
    Passagne I; Evrard A; Winum JY; Depeille P; Cuq P; Montero JL; Cupissol D; Vian L
    J Pharmacol Exp Ther; 2003 Nov; 307(2):816-23. PubMed ID: 12970393
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Extended depletion of O6-methylguanine-DNA methyltransferase activity following O6-benzyl-2'-deoxyguanosine or O6-benzylguanine combined with streptozotocin treatment enhances 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity.
    Marathi UK; Dolan ME; Erickson LC
    Cancer Res; 1994 Aug; 54(16):4371-5. PubMed ID: 8044784
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Circumvention of ACNU-resistance in rat glioma cells by pretreatment with O6-methylguanine].
    Mineura K; Fushimi S; Sasaki J; Sasajima H; Ishino Y; Kowada M
    Gan To Kagaku Ryoho; 1989 Feb; 16(2):259-62. PubMed ID: 2919893
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhanced repair of O6-methylguanine in liver DNA of rats pretreated with phenobarbital, 2,3,7,8-tetrachlorodibenzo-p-dioxin, ethionine, or N-alkyl-N-nitrosoureas.
    Den Engelse L; Floot BG; Menkveld GJ; Tates AD
    Carcinogenesis; 1986 Dec; 7(12):1941-7. PubMed ID: 3779892
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modulation of O6-alkylating agent induced clastogenicity by enhanced DNA repair capacity of bone marrow cells.
    Chinnasamy N; Fairbairn LJ; Laher J; Willington MA; Rafferty JA
    Mutat Res; 1998 Aug; 416(1-2):1-10. PubMed ID: 9725988
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential repair of 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea-induced DNA damage in two human colon tumor cell lines.
    Erickson LC; Osieka R; Kohn KW
    Cancer Res; 1978 Mar; 38(3):802-8. PubMed ID: 626984
    [TBL] [Abstract][Full Text] [Related]  

  • 16. O6-methylguanine-DNA methyltransferase (MGMT) transfectants of a 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-sensitive colon cancer cell line selectively repopulate heterogenous MGMT+/MGMT- xenografts after BCNU and O6-benzylguanine plus BCNU.
    Phillips WP; Willson JK; Markowitz SD; Zborowska E; Zaidi NH; Liu L; Gordon NH; Gerson SL
    Cancer Res; 1997 Nov; 57(21):4817-23. PubMed ID: 9354444
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of O6-benzylguanine on the sensitivity of human colon tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU).
    Dolan ME; Pegg AE; Moschel RC; Grindey GB
    Biochem Pharmacol; 1993 Jul; 46(2):285-90. PubMed ID: 8347150
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhancement of nitrosourea activity in medulloblastoma and glioblastoma multiforme.
    Friedman HS; Dolan ME; Moschel RC; Pegg AE; Felker GM; Rich J; Bigner DD; Schold SC
    J Natl Cancer Inst; 1992 Dec; 84(24):1926-31. PubMed ID: 1334154
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modulation of O6-methylguanine-DNA methyltransferase-mediated 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea resistance by O6-benzylguanine in vitro and in vivo.
    Chen JM; Zhang YP; Sui JL; Moschel RC; Ikenaga M
    Anticancer Res; 1993; 13(3):801-5. PubMed ID: 8317915
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DeltaMGMT-transduced bone marrow infusion increases tolerance to O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea and allows intensive therapy of 1,3-bis(2-chloroethyl)-1-nitrosourea-resistant human colon cancer xenografts.
    Koç ON; Reese JS; Davis BM; Liu L; Majczenko KJ; Gerson SL
    Hum Gene Ther; 1999 Apr; 10(6):1021-30. PubMed ID: 10223735
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 240.