197 related articles for article (PubMed ID: 35981137)
1. MiR-27a downregulates 14-3-3θ, RUNX1, AF4, and MLL-AF4, crucial drivers of blast transformation in t(4;11) leukemia cells.
Fioretti T; Zanobio M; Raia M; Errichiello S; Izzo B; Cattaneo F; Ammendola R; Cevenini A; Esposito G
Cell Biochem Funct; 2022 Oct; 40(7):706-717. PubMed ID: 35981137
[TBL] [Abstract][Full Text] [Related]
2. Crosstalk between 14-3-3θ and AF4 enhances MLL-AF4 activity and promotes leukemia cell proliferation.
Fioretti T; Cevenini A; Zanobio M; Raia M; Sarnataro D; Salvatore F; Esposito G
Cell Oncol (Dordr); 2019 Dec; 42(6):829-845. PubMed ID: 31493143
[TBL] [Abstract][Full Text] [Related]
3. Nuclear FGFR2 Interacts with the MLL-AF4 Oncogenic Chimera and Positively Regulates
Fioretti T; Cevenini A; Zanobio M; Raia M; Sarnataro D; Cattaneo F; Ammendola R; Esposito G
Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33924850
[TBL] [Abstract][Full Text] [Related]
4. MicroRNA-142-3p inhibits cell proliferation in human acute lymphoblastic leukemia by targeting the MLL-AF4 oncogene.
Dou L; Li J; Zheng D; Li Y; Gao X; Xu C; Gao L; Wang L; Yu L
Mol Biol Rep; 2013 Dec; 40(12):6811-9. PubMed ID: 24057258
[TBL] [Abstract][Full Text] [Related]
5. Methylation-mediated repression of microRNA-143 enhances MLL-AF4 oncogene expression.
Dou L; Zheng D; Li J; Li Y; Gao L; Wang L; Yu L
Oncogene; 2012 Jan; 31(4):507-17. PubMed ID: 21706045
[TBL] [Abstract][Full Text] [Related]
6. miR-130b and miR-128a are essential lineage-specific codrivers of t(4;11) MLL-AF4 acute leukemia.
Malouf C; Antunes ETB; O'Dwyer M; Jakobczyk H; Sahm F; Landua SL; Anderson RA; Soufi A; Halsey C; Ottersbach K
Blood; 2021 Nov; 138(21):2066-2092. PubMed ID: 34111240
[TBL] [Abstract][Full Text] [Related]
7. Leukemic fusion genes MLL/AF4 and AML1/MTG8 support leukemic self-renewal by controlling expression of the telomerase subunit TERT.
Gessner A; Thomas M; Castro PG; Büchler L; Scholz A; Brümmendorf TH; Soria NM; Vormoor J; Greil J; Heidenreich O
Leukemia; 2010 Oct; 24(10):1751-9. PubMed ID: 20686504
[TBL] [Abstract][Full Text] [Related]
8. Targeting MLL-AF4 with short interfering RNAs inhibits clonogenicity and engraftment of t(4;11)-positive human leukemic cells.
Thomas M; Gessner A; Vornlocher HP; Hadwiger P; Greil J; Heidenreich O
Blood; 2005 Nov; 106(10):3559-66. PubMed ID: 16046533
[TBL] [Abstract][Full Text] [Related]
9. MicroRNA-205 downregulates mixed-lineage-AF4 oncogene expression in acute lymphoblastic leukemia.
Dou L; Li J; Zheng D; Li Y; Gao X; Xu C; Gao L; Wang L; Yu L
Onco Targets Ther; 2013; 6():1153-60. PubMed ID: 24009426
[TBL] [Abstract][Full Text] [Related]
10. circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression.
Huang W; Fang K; Chen TQ; Zeng ZC; Sun YM; Han C; Sun LY; Chen ZH; Yang QQ; Pan Q; Luo XQ; Wang WT; Chen YQ
J Hematol Oncol; 2019 Oct; 12(1):103. PubMed ID: 31623653
[TBL] [Abstract][Full Text] [Related]
11. miR-128b is a potent glucocorticoid sensitizer in MLL-AF4 acute lymphocytic leukemia cells and exerts cooperative effects with miR-221.
Kotani A; Ha D; Hsieh J; Rao PK; Schotte D; den Boer ML; Armstrong SA; Lodish HF
Blood; 2009 Nov; 114(19):4169-78. PubMed ID: 19749093
[TBL] [Abstract][Full Text] [Related]
12. The heterodimerization domains of MLL-FYRN and FYRC--are potential target structures in t(4;11) leukemia.
Pless B; Oehm C; Knauer S; Stauber RH; Dingermann T; Marschalek R
Leukemia; 2011 Apr; 25(4):663-70. PubMed ID: 21233834
[TBL] [Abstract][Full Text] [Related]
13. Pro-B-cell to pre-B-cell development in B-lineage acute lymphoblastic leukemia expressing the MLL/AF4 fusion protein.
Bertrand FE; Vogtenhuber C; Shah N; LeBien TW
Blood; 2001 Dec; 98(12):3398-405. PubMed ID: 11719380
[TBL] [Abstract][Full Text] [Related]
14. Instructive Role of MLL-Fusion Proteins Revealed by a Model of t(4;11) Pro-B Acute Lymphoblastic Leukemia.
Lin S; Luo RT; Ptasinska A; Kerry J; Assi SA; Wunderlich M; Imamura T; Kaberlein JJ; Rayes A; Althoff MJ; Anastasi J; O'Brien MM; Meetei AR; Milne TA; Bonifer C; Mulloy JC; Thirman MJ
Cancer Cell; 2016 Nov; 30(5):737-749. PubMed ID: 27846391
[TBL] [Abstract][Full Text] [Related]
15. Clinical significance of MLL-AF4 fusion transcript expression in the absence of a cytogenetically detectable t(4;11)(q21;q23) chromosomal translocation.
Uckun FM; Herman-Hatten K; Crotty ML; Sensel MG; Sather HN; Tuel-Ahlgren L; Sarquis MB; Bostrom B; Nachman JB; Steinherz PG; Gaynon PS; Heerema N
Blood; 1998 Aug; 92(3):810-21. PubMed ID: 9680349
[TBL] [Abstract][Full Text] [Related]
16. AAV8 vector expressing IL24 efficiently suppresses tumor growth mediated by specific mechanisms in MLL/AF4-positive ALL model mice.
Tamai H; Miyake K; Yamaguchi H; Takatori M; Dan K; Inokuchi K; Shimada T
Blood; 2012 Jan; 119(1):64-71. PubMed ID: 22025528
[TBL] [Abstract][Full Text] [Related]
17. The AF4.MLL fusion protein is capable of inducing ALL in mice without requirement of MLL.AF4.
Bursen A; Schwabe K; Rüster B; Henschler R; Ruthardt M; Dingermann T; Marschalek R
Blood; 2010 Apr; 115(17):3570-9. PubMed ID: 20194896
[TBL] [Abstract][Full Text] [Related]
18. Bone marrow mesenchymal stem cells from infants with MLL-AF4+ acute leukemia harbor and express the MLL-AF4 fusion gene.
Menendez P; Catalina P; Rodríguez R; Melen GJ; Bueno C; Arriero M; García-Sánchez F; Lassaletta A; García-Sanz R; García-Castro J
J Exp Med; 2009 Dec; 206(13):3131-41. PubMed ID: 19995953
[TBL] [Abstract][Full Text] [Related]
19. RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction.
Wilkinson AC; Ballabio E; Geng H; North P; Tapia M; Kerry J; Biswas D; Roeder RG; Allis CD; Melnick A; de Bruijn MF; Milne TA
Cell Rep; 2013 Jan; 3(1):116-27. PubMed ID: 23352661
[TBL] [Abstract][Full Text] [Related]
20. MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia.
Prange KHM; Mandoli A; Kuznetsova T; Wang SY; Sotoca AM; Marneth AE; van der Reijden BA; Stunnenberg HG; Martens JHA
Oncogene; 2017 Jun; 36(23):3346-3356. PubMed ID: 28114278
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]