170 related articles for article (PubMed ID: 35982823)
1. BTZ-Derived Benzisothiazolinones with In Vitro Activity against
Richter A; Seidel RW; Goddard R; Eckhardt T; Lehmann C; Dörner J; Siersleben F; Sondermann T; Mann L; Patzer M; Jäger C; Reiling N; Imming P
ACS Med Chem Lett; 2022 Aug; 13(8):1302-1310. PubMed ID: 35982823
[TBL] [Abstract][Full Text] [Related]
2. Crystallographic evidence for unintended benzisothiazolinone 1-oxide formation from benzothiazinones through oxidation.
Eckhardt T; Goddard R; Lehmann C; Richter A; Sahile HA; Liu R; Tiwari R; Oliver AG; Miller MJ; Seidel RW; Imming P
Acta Crystallogr C Struct Chem; 2020 Sep; 76(Pt 9):907-913. PubMed ID: 32887862
[TBL] [Abstract][Full Text] [Related]
3. Synthesis, structural characterization and antimycobacterial evaluation of several halogenated non-nitro benzothiazinones.
Madikizela B; Eckhardt T; Goddard R; Richter A; Lins A; Lehmann C; Imming P; Seidel RW
Med Chem Res; 2021; 30(8):1523-1533. PubMed ID: 34131377
[TBL] [Abstract][Full Text] [Related]
4. Syntheses and Antituberculosis Activity of 1,3-Benzothiazinone Sulfoxide and Sulfone Derived from BTZ043.
Tiwari R; Miller PA; Cho S; Franzblau SG; Miller MJ
ACS Med Chem Lett; 2015 Feb; 6(2):128-33. PubMed ID: 25699139
[TBL] [Abstract][Full Text] [Related]
5. Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1.
Richter A; Rudolph I; Möllmann U; Voigt K; Chung CW; Singh OMP; Rees M; Mendoza-Losana A; Bates R; Ballell L; Batt S; Veerapen N; Fütterer K; Besra G; Imming P; Argyrou A
Sci Rep; 2018 Sep; 8(1):13473. PubMed ID: 30194385
[TBL] [Abstract][Full Text] [Related]
6. The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis.
Makarov V; Neres J; Hartkoorn RC; Ryabova OB; Kazakova E; Šarkan M; Huszár S; Piton J; Kolly GS; Vocat A; Conroy TM; Mikušová K; Cole ST
Antimicrob Agents Chemother; 2015 Aug; 59(8):4446-52. PubMed ID: 25987616
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis and evaluation of covalent inhibitors of DprE1 as antitubercular agents.
Liu L; Kong C; Fumagalli M; Savková K; Xu Y; Huszár S; Sammartino JC; Fan D; Chiarelli LR; Mikušová K; Sun Z; Qiao C
Eur J Med Chem; 2020 Dec; 208():112773. PubMed ID: 32898793
[TBL] [Abstract][Full Text] [Related]
8. New Insight into Dearomatization and Decarbonylation of Antitubercular 4H-Benzo[e][1,3]thiazinones: Stable 5H- and 7H-Benzo[e][1,3]thiazines.
Richter A; Seidel RW; Graf J; Goddard R; Lehmann C; Schlegel T; Khater N; Imming P
ChemMedChem; 2022 Mar; 17(6):e202200021. PubMed ID: 35170242
[TBL] [Abstract][Full Text] [Related]
9. Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance.
Manina G; Bellinzoni M; Pasca MR; Neres J; Milano A; Ribeiro AL; Buroni S; Skovierová H; Dianišková P; Mikušová K; Marák J; Makarov V; Giganti D; Haouz A; Lucarelli AP; Degiacomi G; Piazza A; Chiarelli LR; De Rossi E; Salina E; Cole ST; Alzari PM; Riccardi G
Mol Microbiol; 2010 Sep; 77(5):1172-85. PubMed ID: 20624223
[TBL] [Abstract][Full Text] [Related]
10. Characterization of DprE1-Mediated Benzothiazinone Resistance in Mycobacterium tuberculosis.
Foo CS; Lechartier B; Kolly GS; Boy-Röttger S; Neres J; Rybniker J; Lupien A; Sala C; Piton J; Cole ST
Antimicrob Agents Chemother; 2016 Nov; 60(11):6451-6459. PubMed ID: 27527085
[TBL] [Abstract][Full Text] [Related]
11. Thiolates chemically induce redox activation of BTZ043 and related potent nitroaromatic anti-tuberculosis agents.
Tiwari R; Moraski GC; Krchňák V; Miller PA; Colon-Martinez M; Herrero E; Oliver AG; Miller MJ
J Am Chem Soc; 2013 Mar; 135(9):3539-49. PubMed ID: 23402278
[TBL] [Abstract][Full Text] [Related]
12. Clinical isolates of Mycobacterium tuberculosis in four European hospitals are uniformly susceptible to benzothiazinones.
Pasca MR; Degiacomi G; Ribeiro AL; Zara F; De Mori P; Heym B; Mirrione M; Brerra R; Pagani L; Pucillo L; Troupioti P; Makarov V; Cole ST; Riccardi G
Antimicrob Agents Chemother; 2010 Apr; 54(4):1616-8. PubMed ID: 20086151
[TBL] [Abstract][Full Text] [Related]
13. Benzothiazinones: prodrugs that covalently modify the decaprenylphosphoryl-β-D-ribose 2'-epimerase DprE1 of Mycobacterium tuberculosis.
Trefzer C; Rengifo-Gonzalez M; Hinner MJ; Schneider P; Makarov V; Cole ST; Johnsson K
J Am Chem Soc; 2010 Oct; 132(39):13663-5. PubMed ID: 20828197
[TBL] [Abstract][Full Text] [Related]
14. Structure, dynamics, and interaction of Mycobacterium tuberculosis (Mtb) DprE1 and DprE2 examined by molecular modeling, simulation, and electrostatic studies.
Bhutani I; Loharch S; Gupta P; Madathil R; Parkesh R
PLoS One; 2015; 10(3):e0119771. PubMed ID: 25789990
[TBL] [Abstract][Full Text] [Related]
15. In vitro combination studies of benzothiazinone lead compound BTZ043 against Mycobacterium tuberculosis.
Lechartier B; Hartkoorn RC; Cole ST
Antimicrob Agents Chemother; 2012 Nov; 56(11):5790-3. PubMed ID: 22926573
[TBL] [Abstract][Full Text] [Related]
16. Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1.
Trefzer C; Škovierová H; Buroni S; Bobovská A; Nenci S; Molteni E; Pojer F; Pasca MR; Makarov V; Cole ST; Riccardi G; Mikušová K; Johnsson K
J Am Chem Soc; 2012 Jan; 134(2):912-5. PubMed ID: 22188377
[TBL] [Abstract][Full Text] [Related]
17. Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis.
Makarov V; Manina G; Mikusova K; Möllmann U; Ryabova O; Saint-Joanis B; Dhar N; Pasca MR; Buroni S; Lucarelli AP; Milano A; De Rossi E; Belanova M; Bobovska A; Dianiskova P; Kordulakova J; Sala C; Fullam E; Schneider P; McKinney JD; Brodin P; Christophe T; Waddell S; Butcher P; Albrethsen J; Rosenkrands I; Brosch R; Nandi V; Bharath S; Gaonkar S; Shandil RK; Balasubramanian V; Balganesh T; Tyagi S; Grosset J; Riccardi G; Cole ST
Science; 2009 May; 324(5928):801-4. PubMed ID: 19299584
[TBL] [Abstract][Full Text] [Related]
18. Design, Syntheses, and Anti-TB Activity of 1,3-Benzothiazinone Azide and Click Chemistry Products Inspired by BTZ043.
Tiwari R; Miller PA; Chiarelli LR; Mori G; Šarkan M; Centárová I; Cho S; Mikušová K; Franzblau SG; Oliver AG; Miller MJ
ACS Med Chem Lett; 2016 Mar; 7(3):266-70. PubMed ID: 26985313
[TBL] [Abstract][Full Text] [Related]
19. Deuteration of BTZ043 Extends the Lifetime of Meisenheimer Intermediates to the Antituberculosis Nitroso Oxidation State.
Liu R; Krchnak V; Brown SN; Miller MJ
ACS Med Chem Lett; 2019 Oct; 10(10):1462-1466. PubMed ID: 31620234
[TBL] [Abstract][Full Text] [Related]
20. Decaprenylphosphoryl-β-D-ribose 2'-epimerase from Mycobacterium tuberculosis is a magic drug target.
Manina G; Pasca MR; Buroni S; De Rossi E; Riccardi G
Curr Med Chem; 2010; 17(27):3099-108. PubMed ID: 20629622
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
