201 related articles for article (PubMed ID: 35985342)
1. A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma.
Pal S; Kaplan JP; Nguyen H; Stopka SA; Savani MR; Regan MS; Nguyen QD; Jones KL; Moreau LA; Peng J; Dipiazza MG; Perciaccante AJ; Zhu X; Hunsel BR; Liu KX; Alexandrescu S; Drissi R; Filbin MG; McBrayer SK; Agar NYR; Chowdhury D; Haas-Kogan DA
Cancer Cell; 2022 Sep; 40(9):957-972.e10. PubMed ID: 35985342
[TBL] [Abstract][Full Text] [Related]
2. Effect of plasma concentrations of uridine on pyrimidine biosynthesis in cultured L1210 cells.
Karle JM; Anderson LW; Cysyk RL
J Biol Chem; 1984 Jan; 259(1):67-72. PubMed ID: 6323418
[TBL] [Abstract][Full Text] [Related]
3. Uridylate-trapping sugar analogs in combination with inhibitors of uridylate synthesis de novo and 5-fluorouridine.
Keppler D; Fauler J; Gasser T; Holstege A; Leube K; Schulz-Holstege C; Weckbecker G
Adv Enzyme Regul; 1985; 23():61-79. PubMed ID: 2416194
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of the de novo pyrimidine biosynthesis pathway limits ribosomal RNA transcription causing nucleolar stress in glioblastoma cells.
Lafita-Navarro MC; Venkateswaran N; Kilgore JA; Kanji S; Han J; Barnes S; Williams NS; Buszczak M; Burma S; Conacci-Sorrell M
PLoS Genet; 2020 Nov; 16(11):e1009117. PubMed ID: 33201894
[TBL] [Abstract][Full Text] [Related]
5. Uracil nucleotide synthesis in a human breast cancer cell line (MCF-7) and in two drug-resistant sublines that contain increased levels of enzymes of the de novo pyrimidine pathway.
Karle JM; Cowan KH; Chisena CA; Cysyk RL
Mol Pharmacol; 1986 Aug; 30(2):136-41. PubMed ID: 2874477
[TBL] [Abstract][Full Text] [Related]
6. DHODH inhibition impedes glioma stem cell proliferation, induces DNA damage, and prolongs survival in orthotopic glioblastoma xenografts.
Spina R; Mills I; Ahmad F; Chen C; Ames HM; Winkles JA; Woodworth GF; Bar EE
Oncogene; 2022 Dec; 41(50):5361-5372. PubMed ID: 36344676
[TBL] [Abstract][Full Text] [Related]
7. Purine salvage promotes treatment resistance in H3K27M-mutant diffuse midline glioma.
Peterson ER; Sajjakulnukit P; Scott AJ; Heaslip C; Andren A; Wilder-Romans K; Zhou W; Palavalasa S; Korimerla N; Lin A; O'Brien A; Kothari A; Zhao Z; Zhang L; Morgan MA; Venneti S; Koschmann C; Jabado N; Lyssiotis CA; Castro MG; Wahl DR
Cancer Metab; 2024 Apr; 12(1):11. PubMed ID: 38594734
[TBL] [Abstract][Full Text] [Related]
8. De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma.
Shi DD; Savani MR; Levitt MM; Wang AC; Endress JE; Bird CE; Buehler J; Stopka SA; Regan MS; Lin YF; Puliyappadamba VT; Gao W; Khanal J; Evans L; Lee JH; Guo L; Xiao Y; Xu M; Huang B; Jennings RB; Bonal DM; Martin-Sandoval MS; Dang T; Gattie LC; Cameron AB; Lee S; Asara JM; Kornblum HI; Mak TW; Looper RE; Nguyen QD; Signoretti S; Gradl S; Sutter A; Jeffers M; Janzer A; Lehrman MA; Zacharias LG; Mathews TP; Losman JA; Richardson TE; Cahill DP; DeBerardinis RJ; Ligon KL; Xu L; Ly P; Agar NYR; Abdullah KG; Harris IS; Kaelin WG; McBrayer SK
Cancer Cell; 2022 Sep; 40(9):939-956.e16. PubMed ID: 35985343
[TBL] [Abstract][Full Text] [Related]
9. Profiles of pyrimidine biosynthesis, salvage and degradation in disks of potato (Solanum tuberosum L.) tubers.
Katahira R; Ashihara H
Planta; 2002 Sep; 215(5):821-8. PubMed ID: 12244448
[TBL] [Abstract][Full Text] [Related]
10. Influence of ammonium ions on hepatic de novo pyrimidine biosynthesis.
Monks A; Chisena CA; Cysyk RL
Arch Biochem Biophys; 1985 Jan; 236(1):1-10. PubMed ID: 2981502
[TBL] [Abstract][Full Text] [Related]
11. Adaptive rewiring of purine metabolism promotes treatment resistance in H3K27M-mutant diffuse midline glioma.
Peterson ER; Sajjakulnukit P; Scott AJ; Heaslip C; Andren A; Wilder-Romans K; Zhou W; Palavalasa S; Korimerla N; Lin A; Obrien A; Kothari A; Zhao Z; Zhang L; Morgan MA; Venneti S; Koschmann C; Jabado N; Lyssiotis CA; Castro MG; Wahl DR
Res Sq; 2023 Sep; ():. PubMed ID: 37790517
[TBL] [Abstract][Full Text] [Related]
12. Disruption of uridine homeostasis links liver pyrimidine metabolism to lipid accumulation.
Le TT; Ziemba A; Urasaki Y; Hayes E; Brotman S; Pizzorno G
J Lipid Res; 2013 Apr; 54(4):1044-57. PubMed ID: 23355744
[TBL] [Abstract][Full Text] [Related]
13. Super Elongation Complex as a Targetable Dependency in Diffuse Midline Glioma.
Dahl NA; Danis E; Balakrishnan I; Wang D; Pierce A; Walker FM; Gilani A; Serkova NJ; Madhavan K; Fosmire S; Green AL; Foreman NK; Venkataraman S; Vibhakar R
Cell Rep; 2020 Apr; 31(1):107485. PubMed ID: 32268092
[TBL] [Abstract][Full Text] [Related]
14. Optimal therapeutic targeting by HDAC inhibition in biopsy-derived treatment-naïve diffuse midline glioma models.
Vitanza NA; Biery MC; Myers C; Ferguson E; Zheng Y; Girard EJ; Przystal JM; Park G; Noll A; Pakiam F; Winter CA; Morris SM; Sarthy J; Cole BL; Leary SES; Crane C; Lieberman NAP; Mueller S; Nazarian J; Gottardo R; Brusniak MY; Mhyre AJ; Olson JM
Neuro Oncol; 2021 Mar; 23(3):376-386. PubMed ID: 33130903
[TBL] [Abstract][Full Text] [Related]
15. Comparative studies on pyrimidine metabolism in excised cotyledons of Pinus radiata during shoot formation in vitro.
Stasolla C; Loukanina N; Ashihara H; Yeung EC; Thorpe TA
J Plant Physiol; 2007 Apr; 164(4):429-41. PubMed ID: 16600426
[TBL] [Abstract][Full Text] [Related]
16. De novo pyrimidine biosynthesis in the oomycete plant pathogen Phytophthora infestans.
García-Bayona L; Garavito MF; Lozano GL; Vasquez JJ; Myers K; Fry WE; Bernal A; Zimmermann BH; Restrepo S
Gene; 2014 Mar; 537(2):312-21. PubMed ID: 24361203
[TBL] [Abstract][Full Text] [Related]
17. Metabolomics identifies pyrimidine starvation as the mechanism of 5-aminoimidazole-4-carboxamide-1-β-riboside-induced apoptosis in multiple myeloma cells.
Bardeleben C; Sharma S; Reeve JR; Bassilian S; Frost P; Hoang B; Shi Y; Lichtenstein A
Mol Cancer Ther; 2013 Jul; 12(7):1310-21. PubMed ID: 23585020
[TBL] [Abstract][Full Text] [Related]
18. Regulation of pyrimidine biosynthesis in cultured L1210 cells by 3-deazauridine.
Karle JM; Cysyk RL
Biochem Pharmacol; 1984 Dec; 33(23):3739-42. PubMed ID: 6095859
[TBL] [Abstract][Full Text] [Related]
19. Biosynthesis and scavenging of pyrimidines by pathogenic mycobacteria.
Wheeler PR
J Gen Microbiol; 1990 Jan; 136(1):189-201. PubMed ID: 2191077
[TBL] [Abstract][Full Text] [Related]
20. Trypanosoma brucei (UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy.
Ong HB; Sienkiewicz N; Wyllie S; Patterson S; Fairlamb AH
Mol Microbiol; 2013 Oct; 90(2):443-55. PubMed ID: 23980694
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]