155 related articles for article (PubMed ID: 3599031)
1. N10-substituted 5,8-dideazafolate inhibitors of glycinamide ribonucleotide transformylase.
Caperelli CA
J Med Chem; 1987 Jul; 30(7):1254-6. PubMed ID: 3599031
[TBL] [Abstract][Full Text] [Related]
2. Synthesis of 10-acetyl-5,8-dideazafolic acid: a potent inhibitor of glycinamide ribonucleotide transformylase.
Caperelli CA; Conigliaro J
J Med Chem; 1986 Oct; 29(10):2117-9. PubMed ID: 3761327
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, and biological evaluation of simplified alpha-keto heterocycle, trifluoromethyl ketone, and formyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase.
Marsilje TH; Hedrick MP; Desharnais J; Tavassoli A; Zhang Y; Wilson IA; Benkovic SJ; Boger DL
Bioorg Med Chem; 2003 Oct; 11(20):4487-501. PubMed ID: 13129585
[TBL] [Abstract][Full Text] [Related]
4. On the cofactor specificity of glycinamide ribonucleotide and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase from chicken liver.
Smith GK; Mueller WT; Benkovic PA; Benkovic SJ
Biochemistry; 1981 Mar; 20(5):1241-5. PubMed ID: 7225325
[TBL] [Abstract][Full Text] [Related]
5. Subcloning, characterization, and affinity labeling of Escherichia coli glycinamide ribonucleotide transformylase.
Inglese J; Johnson DL; Shiau A; Smith JM; Benkovic SJ
Biochemistry; 1990 Feb; 29(6):1436-43. PubMed ID: 2185839
[TBL] [Abstract][Full Text] [Related]
6. Mammalian glycinamide ribonucleotide transformylase: purification and some properties.
Caperelli CA
Biochemistry; 1985 Mar; 24(6):1316-20. PubMed ID: 3986180
[TBL] [Abstract][Full Text] [Related]
7. Side chain modified 5-deazafolate and 5-deazatetrahydrofolate analogues as mammalian folylpolyglutamate synthetase and glycinamide ribonucleotide formyltransferase inhibitors: synthesis and in vitro biological evaluation.
Rosowsky A; Forsch RA; Reich VE; Freisheim JH; Moran RG
J Med Chem; 1992 May; 35(9):1578-88. PubMed ID: 1578484
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and biological evaluation of 10-CF3CO-DDACTHF analogues and derivatives as inhibitors of GAR Tfase and the de novo purine biosynthetic pathway.
Desharnais J; Hwang I; Zhang Y; Tavassoli A; Baboval J; Benkovic SJ; Wilson IA; Boger DL
Bioorg Med Chem; 2003 Oct; 11(20):4511-21. PubMed ID: 13129587
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis, and biological evaluation of fluoronitrophenyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase.
Boger DL; Marsilje TH; Castro RA; Hedrick MP; Jin Q; Baker SJ; Shim JH; Benkovic SJ
Bioorg Med Chem Lett; 2000 Jul; 10(13):1471-5. PubMed ID: 10888335
[TBL] [Abstract][Full Text] [Related]
10. Synthesis of 5,11-methenyltetrahydrohomofolate and its antifolate activity in vitro.
Caperelli CA; Domanico P; Benkovic SJ
J Med Chem; 1981 Sep; 24(9):1086-8. PubMed ID: 7288824
[TBL] [Abstract][Full Text] [Related]
11. Mammalian glycinamide ribonucleotide transformylase. Kinetic mechanism and associated de novo purine biosynthetic activities.
Caperelli CA
J Biol Chem; 1989 Mar; 264(9):5053-7. PubMed ID: 2925682
[TBL] [Abstract][Full Text] [Related]
12. Active-site mapping and site-specific mutagenesis of glycinamide ribonucleotide transformylase from Escherichia coli.
Inglese J; Smith JM; Benkovic SJ
Biochemistry; 1990 Jul; 29(28):6678-87. PubMed ID: 2204419
[TBL] [Abstract][Full Text] [Related]
13. Carbocyclic glycinamide ribonucleotide is a substrate for glycinamide ribonucleotide transformylase.
Caperelli CA; Price MF
Arch Biochem Biophys; 1988 Jul; 264(1):340-2. PubMed ID: 3395127
[TBL] [Abstract][Full Text] [Related]
14. 10-Formyl-5,8,10-trideazafolic acid (10-formyl-TDAF): a potent inhibitor of glycinamide ribonucleotide transformylase.
Boger DL; Haynes NE; Kitos PA; Warren MS; Ramcharan J; Marolewski AE; Benkovic SJ
Bioorg Med Chem; 1997 Sep; 5(9):1817-30. PubMed ID: 9354237
[TBL] [Abstract][Full Text] [Related]
15. L(-)-10-Formyltetrahydrofolate is the cofactor for glycinamide ribonucleotide transformylase from chicken liver.
Smith GK; Benkovic PA; Benkovic SJ
Biochemistry; 1981 Jul; 20(14):4034-6. PubMed ID: 7284307
[TBL] [Abstract][Full Text] [Related]
16. Structural and mechanistic studies on the HeLa and chicken liver proteins that catalyze glycinamide ribonucleotide synthesis and formylation and aminoimidazole ribonucleotide synthesis.
Daubner SC; Young M; Sammons RD; Courtney LF; Benkovic SJ
Biochemistry; 1986 May; 25(10):2951-7. PubMed ID: 3718932
[TBL] [Abstract][Full Text] [Related]
17. 10-(2-benzoxazolcarbonyl)-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid: a potential inhibitor of GAR transformylase and AICAR transformylase.
Marsilje TH; Hedrick MP; Desharnais J; Capps K; Tavassoli A; Zhang Y; Wilson IA; Benkovic SJ; Boger DL
Bioorg Med Chem; 2003 Oct; 11(20):4503-9. PubMed ID: 13129586
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of HKSV28 cell growth by 5,11-methenyl-tetrahydrohomofolate.
Slieker LJ; Benkovic SJ
Mol Pharmacol; 1984 Mar; 25(2):294-302. PubMed ID: 6700575
[TBL] [Abstract][Full Text] [Related]
19. Abenzyl 10-formyl-trideazafolic acid (abenzyl 10-formyl-TDAF): an effective inhibitor of glycinamide ribonucleotide transformylase.
Boger DL; Haynes NE; Warren MS; Ramcharan J; Marolewski AE; Kitos PA; Benkovic SJ
Bioorg Med Chem; 1997 Sep; 5(9):1847-52. PubMed ID: 9354240
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of chicken liver 5-aminoimidazole-4-carboxamide ribonucleotide transformylase by 5,8-dideaza analogues of folic acid.
Mueller WT; Smith GK; Benkovic SJ; Hynes JB
Biochem Pharmacol; 1988 Feb; 37(3):449-51. PubMed ID: 3337744
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]