131 related articles for article (PubMed ID: 35998389)
1. Conformational change in ricin toxin A-Chain: A critical factor for inhibitor binding to the secondary pocket.
Goto M; Higashi S; Ohba T; Kawata R; Nagatsu K; Suzuki S; Anslyn EV; Saito R
Biochem Biophys Res Commun; 2022 Oct; 627():1-4. PubMed ID: 35998389
[TBL] [Abstract][Full Text] [Related]
2. Crystal structure of ricin toxin A chain complexed with a highly potent pterin-based small-molecular inhibitor.
Goto M; Sakamoto N; Higashi S; Kawata R; Nagatsu K; Saito R
J Enzyme Inhib Med Chem; 2023 Dec; 38(1):2219038. PubMed ID: 37259593
[TBL] [Abstract][Full Text] [Related]
3. Pterin-based small molecule inhibitor capable of binding to the secondary pocket in the active site of ricin-toxin A chain.
Saito R; Goto M; Katakura S; Ohba T; Kawata R; Nagatsu K; Higashi S; Kurisu K; Matsumoto K; Ohtsuka K
PLoS One; 2022; 17(12):e0277770. PubMed ID: 36508422
[TBL] [Abstract][Full Text] [Related]
4. Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site.
Carra JH; McHugh CA; Mulligan S; Machiesky LM; Soares AS; Millard CB
BMC Struct Biol; 2007 Nov; 7():72. PubMed ID: 17986339
[TBL] [Abstract][Full Text] [Related]
5. Small Molecule Inhibitors Targeting the Interaction of Ricin Toxin A Subunit with Ribosomes.
Li XP; Harijan RK; Kahn JN; Schramm VL; Tumer NE
ACS Infect Dis; 2020 Jul; 6(7):1894-1905. PubMed ID: 32428396
[TBL] [Abstract][Full Text] [Related]
6. Real-time kinetic analyses of the interaction of ricin toxin A-chain with ribosomes prove a conformational change involved in complex formation.
Honjo E; Watanabe K; Tsukamoto T
J Biochem; 2002 Feb; 131(2):267-75. PubMed ID: 11820942
[TBL] [Abstract][Full Text] [Related]
7. Leucine 232 and hydrophobic residues at the ribosomal P stalk binding site are critical for biological activity of ricin.
Zhou Y; Li XP; Kahn JN; McLaughlin JE; Tumer NE
Biosci Rep; 2019 Oct; 39(10):. PubMed ID: 31548364
[TBL] [Abstract][Full Text] [Related]
8. Structure-based identification of a ricin inhibitor.
Yan X; Hollis T; Svinth M; Day P; Monzingo AF; Milne GW; Robertus JD
J Mol Biol; 1997 Mar; 266(5):1043-9. PubMed ID: 9086280
[TBL] [Abstract][Full Text] [Related]
9. Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin.
Rudolph MJ; Dutta A; Tsymbal AM; McLaughlin JE; Chen Y; Davis SA; Theodorous SA; Pierce M; Algava B; Zhang X; Szekely Z; Roberge JY; Li XP; Tumer NE
Bioorg Med Chem; 2024 Feb; 100():117614. PubMed ID: 38340640
[TBL] [Abstract][Full Text] [Related]
10. Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P-stalk proteins.
Czajka TF; Vance DJ; Davis S; Rudolph MJ; Mantis NJ
J Biol Chem; 2022 Apr; 298(4):101742. PubMed ID: 35182523
[TBL] [Abstract][Full Text] [Related]
11. Peptide Mimics of the Ribosomal P Stalk Inhibit the Activity of Ricin A Chain by Preventing Ribosome Binding.
Li XP; Kahn JN; Tumer NE
Toxins (Basel); 2018 Sep; 10(9):. PubMed ID: 30217009
[TBL] [Abstract][Full Text] [Related]
12. The X-ray structure of ricin A chain with a novel inhibitor.
Bai Y; Monzingo AF; Robertus JD
Arch Biochem Biophys; 2009 Mar; 483(1):23-8. PubMed ID: 19138659
[TBL] [Abstract][Full Text] [Related]
13. Ricin toxin contains at least three galactose-binding sites located in B chain subdomains 1 alpha, 1 beta, and 2 gamma.
Frankel AE; Burbage C; Fu T; Tagge E; Chandler J; Willingham MC
Biochemistry; 1996 Nov; 35(47):14749-56. PubMed ID: 8942636
[TBL] [Abstract][Full Text] [Related]
14. Determining the Relative Binding Affinity of Ricin Toxin A Inhibitors by Using Molecular Docking and Nonequilibrium Work.
Chaves EJF; Padilha IQM; Araújo DAM; Rocha GB
J Chem Inf Model; 2018 Jun; 58(6):1205-1213. PubMed ID: 29750861
[TBL] [Abstract][Full Text] [Related]
15. Toxicity of ricin A chain is reduced in mammalian cells by inhibiting its interaction with the ribosome.
Jetzt AE; Li XP; Tumer NE; Cohick WS
Toxicol Appl Pharmacol; 2016 Nov; 310():120-128. PubMed ID: 27639428
[TBL] [Abstract][Full Text] [Related]
16. A two-step binding model proposed for the electrostatic interactions of ricin a chain with ribosomes.
Li XP; Chiou JC; Remacha M; Ballesta JP; Tumer NE
Biochemistry; 2009 May; 48(18):3853-63. PubMed ID: 19292477
[TBL] [Abstract][Full Text] [Related]
17. The P1/P2 proteins of the human ribosomal stalk are required for ribosome binding and depurination by ricin in human cells.
May KL; Li XP; Martínez-Azorín F; Ballesta JP; Grela P; Tchórzewski M; Tumer NE
FEBS J; 2012 Oct; 279(20):3925-36. PubMed ID: 22909382
[TBL] [Abstract][Full Text] [Related]
18. Structure and activity of an active site substitution of ricin A chain.
Day PJ; Ernst SR; Frankel AE; Monzingo AF; Pascal JM; Molina-Svinth MC; Robertus JD
Biochemistry; 1996 Aug; 35(34):11098-103. PubMed ID: 8780513
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of ricin A-chain (RTA) catalytic activity by a viral genome-linked protein (VPg).
Aitbakieva VR; Ahmad R; Singh S; Domashevskiy AV
Biochim Biophys Acta Proteins Proteom; 2019 Jun; 1867(6):645-653. PubMed ID: 30822539
[TBL] [Abstract][Full Text] [Related]
20. Ricin A Chain from Ricinus sanguineus: DNA sequence, structure and toxicity.
El-Nikhely N; Helmy M; Saeed HM; Abou Shama LA; Abd El-Rahman Z
Protein J; 2007 Oct; 26(7):481-9. PubMed ID: 17687522
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
