These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 35998389)

  • 21. Ligand based virtual screening to find novel inhibitors against plant toxin Ricin by using the ZINC database.
    Mishra V; Siva Prasad CV
    Bioinformation; 2011; 7(2):46-51. PubMed ID: 21938204
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Ribosome depurination by ricin leads to inhibition of endoplasmic reticulum stress-induced
    Pierce M; Vengsarkar D; McLaughlin JE; Kahn JN; Tumer NE
    J Biol Chem; 2019 Nov; 294(47):17848-17862. PubMed ID: 31624149
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A fluorescence anisotropy-based competition assay to identify inhibitors against ricin and Shiga toxin ribosome interactions.
    Dutta A; Szekely Z; Guven H; Li XP; McLaughlin JE; Tumer NE
    Anal Biochem; 2024 Sep; 692():115580. PubMed ID: 38825159
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis and Structural Characterization of Ricin Inhibitors Targeting Ribosome Binding Using Fragment-Based Methods and Structure-Based Design.
    Li XP; Harijan RK; Cao B; Kahn JN; Pierce M; Tsymbal AM; Roberge JY; Augeri D; Tumer NE
    J Med Chem; 2021 Oct; 64(20):15334-15348. PubMed ID: 34648707
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Stability of isolated antibody-antigen complexes as a predictive tool for selecting toxin neutralizing antibodies.
    Legler PM; Compton JR; Hale ML; Anderson GP; Olson MA; Millard CB; Goldman ER
    MAbs; 2017 Jan; 9(1):43-57. PubMed ID: 27660893
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Arginine residues on the opposite side of the active site stimulate the catalysis of ribosome depurination by ricin A chain by interacting with the P-protein stalk.
    Li XP; Kahn PC; Kahn JN; Grela P; Tumer NE
    J Biol Chem; 2013 Oct; 288(42):30270-30284. PubMed ID: 24003229
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Ricin uses arginine 235 as an anchor residue to bind to P-proteins of the ribosomal stalk.
    Zhou Y; Li XP; Chen BY; Tumer NE
    Sci Rep; 2017 Feb; 7():42912. PubMed ID: 28230053
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum.
    Spooner RA; Hart PJ; Cook JP; Pietroni P; Rogon C; Höhfeld J; Roberts LM; Lord JM
    Proc Natl Acad Sci U S A; 2008 Nov; 105(45):17408-13. PubMed ID: 18988734
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Alteration of an amino acid residue outside the active site of the ricin A chain reduces its toxicity towards yeast ribosomes.
    Gould JH; Hartley MR; Welsh PC; Hoshizaki DK; Frankel A; Roberts LM; Lord JM
    Mol Gen Genet; 1991 Nov; 230(1-2):81-90. PubMed ID: 1745246
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Generation of a potent chimeric toxin by replacement of domain III of Pseudomonas exotoxin with ricin A chain KDEL.
    Pitcher C; Roberts L; Fawell S; Zdanovsky AG; FitzGerald DJ; Lord JM
    Bioconjug Chem; 1995; 6(5):624-9. PubMed ID: 8974463
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Differences in cytotoxicity of native and engineered RIPs can be used to assess their ability to reach the cytoplasm.
    Svinth M; Steighardt J; Hernandez R; Suh JK; Kelly C; Day P; Lord M; Girbes T; Robertus JD
    Biochem Biophys Res Commun; 1998 Aug; 249(3):637-42. PubMed ID: 9731188
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The ribosomal stalk is required for ribosome binding, depurination of the rRNA and cytotoxicity of ricin A chain in Saccharomyces cerevisiae.
    Chiou JC; Li XP; Remacha M; Ballesta JP; Tumer NE
    Mol Microbiol; 2008 Dec; 70(6):1441-52. PubMed ID: 19019145
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation.
    Sokołowska I; Wälchli S; Węgrzyn G; Sandvig K; Słomińska-Wojewódzka M
    Biochem J; 2011 Jun; 436(2):371-85. PubMed ID: 21388347
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
    Rudolph MJ; Czajka TF; Davis SA; Thi Nguyen CM; Li XP; Tumer NE; Vance DJ; Mantis NJ
    J Mol Biol; 2020 Feb; 432(4):1109-1125. PubMed ID: 31931008
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Identification and Biological Evaluation of a Novel Small-Molecule Inhibitor of Ricin Toxin.
    Yang X; Wei A; Cao X; Wang Z; Wan H; Wang B; Peng H
    Molecules; 2024 Mar; 29(7):. PubMed ID: 38611715
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Binding of ricin A-chain to negatively charged phospholipid vesicles leads to protein structural changes and destabilizes the lipid bilayer.
    Day PJ; Pinheiro TJ; Roberts LM; Lord JM
    Biochemistry; 2002 Feb; 41(8):2836-43. PubMed ID: 11851431
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Novel class of potential therapeutics that target ricin retrograde translocation.
    Redmann V; Gardner T; Lau Z; Morohashi K; Felsenfeld D; Tortorella D
    Toxins (Basel); 2013 Dec; 6(1):33-53. PubMed ID: 24366208
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Cytotoxic ribosome-inactivating lectins from plants.
    Hartley MR; Lord JM
    Biochim Biophys Acta; 2004 Sep; 1701(1-2):1-14. PubMed ID: 15450171
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Baicalin inhibits the lethality of ricin in mice by inducing protein oligomerization.
    Dong J; Zhang Y; Chen Y; Niu X; Zhang Y; Li R; Yang C; Wang Q; Li X; Deng X
    J Biol Chem; 2015 May; 290(20):12899-907. PubMed ID: 25847243
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain.
    Marsden CJ; Fülöp V; Day PJ; Lord JM
    Eur J Biochem; 2004 Jan; 271(1):153-62. PubMed ID: 14686928
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.