BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 36001679)

  • 41. Constitutive activation of Lck and Fyn tyrosine kinases in large granular lymphocytes infected with the gamma-herpesvirus agents of malignant catarrhal fever.
    Swa S; Wright H; Thomson J; Reid H; Haig D
    Immunology; 2001 Jan; 102(1):44-52. PubMed ID: 11168636
    [TBL] [Abstract][Full Text] [Related]  

  • 42. CBP Modulates Sensitivity to Dasatinib in Pre-BCR
    Duque-Afonso J; Lin CH; Han K; Morgens DW; Jeng EE; Weng Z; Jeong J; Wong SHK; Zhu L; Wei MC; Chae HD; Schrappe M; Cario G; Duyster J; Xiao X; Sakamoto KM; Bassik MC; Cleary ML
    Cancer Res; 2018 Nov; 78(22):6497-6508. PubMed ID: 30262461
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity.
    Martin MW; Newcomb J; Nunes JJ; Boucher C; Chai L; Epstein LF; Faust T; Flores S; Gallant P; Gore A; Gu Y; Hsieh F; Huang X; Kim JL; Middleton S; Morgenstern K; Oliveira-dos-Santos A; Patel VF; Powers D; Rose P; Tudor Y; Turci SM; Welcher AA; Zack D; Zhao H; Zhu L; Zhu X; Ghiron C; Ermann M; Johnston D; Saluste CG
    J Med Chem; 2008 Mar; 51(6):1637-48. PubMed ID: 18278858
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Impact of T-cell immunity on chemotherapy response in childhood acute lymphoblastic leukemia.
    Li Y; Yang X; Sun Y; Li Z; Yang W; Ju B; Easton J; Pei D; Cheng C; Lee S; Pui CH; Yu J; Chi H; Yang JJ
    Blood; 2022 Sep; 140(13):1507-1521. PubMed ID: 35675514
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Protein tyrosine kinase p56-Lck regulates lymphocyte function-associated 1 adhesion molecule expression, granule exocytosis, and cytolytic effector function in a cloned T cell.
    Torigoe T; Millan JA; Chan KW; Taichman R; Brian AA; Reed JC; Tachman R [corrected to Taichman R]
    J Exp Med; 1994 Sep; 180(3):1115-27. PubMed ID: 7914906
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Downregulation of p56(lck) tyrosine kinase activity in T cells of squirrel monkeys (Saimiri sciureus) correlates with the nontransforming and apathogenic properties of herpesvirus saimiri in its natural host.
    Greve T; Tamgüney G; Fleischer B; Fickenscher H; Bröker BM
    J Virol; 2001 Oct; 75(19):9252-61. PubMed ID: 11533187
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Lymphocyte-specific protein tyrosine kinase (Lck) interacts with CR6-interacting factor 1 (CRIF1) in mitochondria to repress oxidative phosphorylation.
    Vahedi S; Chueh FY; Chandran B; Yu CL
    BMC Cancer; 2015 Jul; 15():551. PubMed ID: 26210498
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Lck protein tyrosine kinase is a key regulator of T-cell activation and a target for signal intervention by Herpesvirus saimiri and other viral gene products.
    Isakov N; Biesinger B
    Eur J Biochem; 2000 Jun; 267(12):3413-21. PubMed ID: 10848956
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Subcellular distribution of Lck during CD4 T-cell maturation in the thymic medulla regulates the T-cell activation threshold.
    Stephen TL; Wilson BS; Laufer TM
    Proc Natl Acad Sci U S A; 2012 May; 109(19):7415-20. PubMed ID: 22529380
    [TBL] [Abstract][Full Text] [Related]  

  • 50. The EMT/ITK/TSK (EMT) tyrosine kinase is activated during TCR signaling: LCK is required for optimal activation of EMT.
    Gibson S; August A; Kawakami Y; Kawakami T; Dupont B; Mills GB
    J Immunol; 1996 Apr; 156(8):2716-22. PubMed ID: 8609388
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Evidence of LAT as a dual substrate for Lck and Syk in T lymphocytes.
    Jiang Y; Cheng H
    Leuk Res; 2007 Apr; 31(4):541-5. PubMed ID: 16938345
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Combination therapy of BCR-ABL-positive B cell acute lymphoblastic leukemia by tyrosine kinase inhibitor dasatinib and c-JUN N-terminal kinase inhibition.
    Xiao X; Liu P; Li D; Xia Z; Wang P; Zhang X; Liu M; Liao L; Jiao B; Ren R
    J Hematol Oncol; 2020 Jun; 13(1):80. PubMed ID: 32552902
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Lck and the nature of the T cell receptor trigger.
    Davis SJ; van der Merwe PA
    Trends Immunol; 2011 Jan; 32(1):1-5. PubMed ID: 21190897
    [TBL] [Abstract][Full Text] [Related]  

  • 54. An oncogenic tyrosine kinase inhibits DNA repair and DNA-damage-induced Bcl-xL deamidation in T cell transformation.
    Zhao R; Yang FT; Alexander DR
    Cancer Cell; 2004 Jan; 5(1):37-49. PubMed ID: 14749125
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Dasatinib: a tyrosine kinase inhibitor for the treatment of chronic myelogenous leukemia and philadelphia chromosome-positive acute lymphoblastic leukemia.
    Steinberg M
    Clin Ther; 2007 Nov; 29(11):2289-308. PubMed ID: 18158072
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Nuclear localization of lymphocyte-specific protein tyrosine kinase (Lck) and its role in regulating LIM domain only 2 (Lmo2) gene.
    Venkitachalam S; Chueh FY; Yu CL
    Biochem Biophys Res Commun; 2012 Jan; 417(3):1058-62. PubMed ID: 22222369
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Integrin-mediated tyrosine phosphorylation of Shc in T cells is regulated by protein kinase C-dependent phosphorylations of Lck.
    Niu S; Xie H; Marcantonio EE
    Mol Biol Cell; 2003 Feb; 14(2):349-60. PubMed ID: 12589038
    [TBL] [Abstract][Full Text] [Related]  

  • 58. 7,12-Dimethylbenz[a]anthracene activates protein-tyrosine kinases Fyn and Lck in the HPB-ALL human T-cell line and increases tyrosine phosphorylation of phospholipase C-gamma 1, formation of inositol 1,4,5-trisphosphate, and mobilization of intracellular calcium.
    Archuleta MM; Schieven GL; Ledbetter JA; Deanin GG; Burchiel SW
    Proc Natl Acad Sci U S A; 1993 Jul; 90(13):6105-9. PubMed ID: 8327490
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Dasatinib as an investigational drug for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia in adults.
    Brattås MK; Reikvam H; Tvedt THA; Bruserud Ø
    Expert Opin Investig Drugs; 2019 May; 28(5):411-420. PubMed ID: 30916583
    [TBL] [Abstract][Full Text] [Related]  

  • 60. p56Lck tyrosine kinase enhances the assembly of death-inducing signaling complex during Fas-mediated apoptosis.
    Sharif-Askari E; Gaucher D; Halwani R; Ma J; Jao K; Abdallah A; Haddad EK; Sékaly RP
    J Biol Chem; 2007 Dec; 282(49):36048-56. PubMed ID: 17932036
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.