BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

150 related articles for article (PubMed ID: 36003621)

  • 1. Design, Synthesis, and Activity Assays of Cyclin-Dependent Kinase 1 Inhibitors With Flavone Scaffolds.
    Fu L; Mou J; Deng Y; Ren X; Qiu S
    Front Chem; 2022; 10():940427. PubMed ID: 36003621
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and primary activity assays of baicalein derivatives as cyclin-dependent kinase 1 inhibitors.
    Mou J; Qiu S; Chen D; Deng Y; Tekleab T
    Chem Biol Drug Des; 2021 Oct; 98(4):639-654. PubMed ID: 34233076
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells.
    Carlson BA; Dubay MM; Sausville EA; Brizuela L; Worland PJ
    Cancer Res; 1996 Jul; 56(13):2973-8. PubMed ID: 8674031
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Eco-friendly sequential one-pot synthesis, molecular docking, and anticancer evaluation of arylidene-hydrazinyl-thiazole derivatives as CDK2 inhibitors.
    El-Naggar AM; El-Hashash MA; Elkaeed EB
    Bioorg Chem; 2021 Mar; 108():104615. PubMed ID: 33484942
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and Biological Evaluation of Scutellaria Flavone Cyclaneaminol Mannich Base Derivatives as Novel CDK1 Inhibitors.
    Ha L; Qian Y; Zhang S; Ju X; Sun S; Guo H; Wang Q; Li K; Fan Q; Zheng Y; Li H
    Anticancer Agents Med Chem; 2016; 16(7):914-24. PubMed ID: 26411959
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, Molecular Docking and Biological Evaluation of Novel Flavone Derivatives as Potential Anticancer Agents Targeting Akt.
    Abo-Salem HM; Gibriel AA; El Awady ME; Mandour AH
    Med Chem; 2021; 17(2):158-170. PubMed ID: 32141421
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of a promising hit from a new series of pyrazolo[1,5-a]pyrimidine based compounds as a potential anticancer agent with potent CDK1 inhibitory and pro-apoptotic properties through a multistep in vitro assessment.
    Elgiushy HR; Mohamed SH; Taha H; Sawaf H; Hassan Z; Abou-Taleb NA; El-Labbad EM; Hassan AS; Abouzid KAM; Hammad SF
    Bioorg Chem; 2022 Mar; 120():105646. PubMed ID: 35134645
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, Biological Evaluation and In Silico Studies of Certain Oxindole-Indole Conjugates as Anticancer CDK Inhibitors.
    Al-Warhi T; El Kerdawy AM; Aljaeed N; Ismael OE; Ayyad RR; Eldehna WM; Abdel-Aziz HA; Al-Ansary GH
    Molecules; 2020 Apr; 25(9):. PubMed ID: 32349307
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, Synthesis, and Molecular Docking of Paracyclophanyl-Thiazole Hybrids as Novel CDK1 Inhibitors and Apoptosis Inducing Anti-Melanoma Agents.
    Aly AA; Bräse S; Hassan AA; Mohamed NK; El-Haleem LEA; Nieger M; Morsy NM; Alshammari MB; Ibrahim MAA; Abdelhafez EMN
    Molecules; 2020 Nov; 25(23):. PubMed ID: 33260954
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, in vitro anticancer activity and in silico studies of certain pyrazole-based derivatives as potential inhibitors of cyclin dependent kinases (CDKs).
    Mohammed EZ; Mahmoud WR; George RF; Hassan GS; Omar FA; Georgey HH
    Bioorg Chem; 2021 Nov; 116():105347. PubMed ID: 34555628
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A New Oxadiazole-Based Topsentin Derivative Modulates Cyclin-Dependent Kinase 1 Expression and Exerts Cytotoxic Effects on Pancreatic Cancer Cells.
    Pecoraro C; Parrino B; Cascioferro S; Puerta A; Avan A; Peters GJ; Diana P; Giovannetti E; Carbone D
    Molecules; 2021 Dec; 27(1):. PubMed ID: 35011251
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibitors of Cyclin-Dependent Kinase 1/2 for Anticancer Treatment.
    Mou J; Chen D; Deng Y
    Med Chem; 2020; 16(3):307-325. PubMed ID: 31241436
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles.
    Arris CE; Boyle FT; Calvert AH; Curtin NJ; Endicott JA; Garman EF; Gibson AE; Golding BT; Grant S; Griffin RJ; Jewsbury P; Johnson LN; Lawrie AM; Newell DR; Noble ME; Sausville EA; Schultz R; Yu W
    J Med Chem; 2000 Jul; 43(15):2797-804. PubMed ID: 10956187
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, Synthesis, In Vitro Anti-cancer Activity, ADMET Profile and Molecular Docking of Novel Triazolo[3,4-a]phthalazine Derivatives Targeting VEGFR-2 Enzyme.
    El-Helby AA; Sakr H; Ayyad RRA; El-Adl K; Ali MM; Khedr F
    Anticancer Agents Med Chem; 2018; 18(8):1184-1196. PubMed ID: 29651967
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of a class of diheteroaromatic amines as orally bioavailable CDK1/4/6 inhibitors.
    Fu Y; Tang S; Su Y; Lan X; Ye Y; Zha C; Li L; Cao J; Chen Y; Jiang L; Huang Y; Ding J; Geng M; Huang M; Wan H
    Bioorg Med Chem Lett; 2017 Dec; 27(23):5332-5336. PubMed ID: 29074254
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cyclin-dependent protein kinase inhibitors including palbociclib as anticancer drugs.
    Roskoski R
    Pharmacol Res; 2016 May; 107():249-275. PubMed ID: 26995305
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular models of cyclin-dependent kinase 1 complexed with inhibitors.
    Canduri F; Uchoa HB; de Azevedo WF
    Biochem Biophys Res Commun; 2004 Nov; 324(2):661-6. PubMed ID: 15474478
    [TBL] [Abstract][Full Text] [Related]  

  • 18. C-glycosyl flavone from
    Bevara GB; Naveen Kumar AD; Koteshwaramma KL; Badana A; Kumari S; Malla RR
    Indian J Med Res; 2018 Feb; 147(2):158-168. PubMed ID: 29806604
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 3D-QSAR CoMFA study on oxindole derivatives as cyclin dependent kinase 1 (CDK1) and cyclin dependent kinase 2 (CDK2) inhibitors.
    Singh SK; Dessalew N; Bharatam PV
    Med Chem; 2007 Jan; 3(1):75-84. PubMed ID: 17266627
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pulchranin A: First report of isolation from an endophytic fungus and its inhibitory activity on cyclin dependent kinases.
    Moussa AY; Mostafa NM; Singab ANB
    Nat Prod Res; 2020 Oct; 34(19):2715-2722. PubMed ID: 30887847
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.