BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 36009039)

  • 1. The Catalytic Domain Mediates Homomultimerization of MT1-MMP and the Prodomain Interferes with MT1-MMP Oligomeric Complex Assembly.
    Fogarasi M; Dima S
    Biomolecules; 2022 Aug; 12(8):. PubMed ID: 36009039
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Collagen binding properties of the membrane type-1 matrix metalloproteinase (MT1-MMP) hemopexin C domain. The ectodomain of the 44-kDa autocatalytic product of MT1-MMP inhibits cell invasion by disrupting native type I collagen cleavage.
    Tam EM; Wu YI; Butler GS; Stack MS; Overall CM
    J Biol Chem; 2002 Oct; 277(41):39005-14. PubMed ID: 12145314
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oligomerization through hemopexin and cytoplasmic domains regulates the activity and turnover of membrane-type 1 matrix metalloproteinase.
    Lehti K; Lohi J; Juntunen MM; Pei D; Keski-Oja J
    J Biol Chem; 2002 Mar; 277(10):8440-8. PubMed ID: 11779859
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Distinct roles for the catalytic and hemopexin domains of membrane type 1-matrix metalloproteinase in substrate degradation and cell migration.
    Cao J; Kozarekar P; Pavlaki M; Chiarelli C; Bahou WF; Zucker S
    J Biol Chem; 2004 Apr; 279(14):14129-39. PubMed ID: 14729674
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sequence motifs of tissue inhibitor of metalloproteinases 2 (TIMP-2) determining progelatinase A (proMMP-2) binding and activation by membrane-type metalloproteinase 1 (MT1-MMP).
    Worley JR; Thompkins PB; Lee MH; Hutton M; Soloway P; Edwards DR; Murphy G; Knäuper V
    Biochem J; 2003 Jun; 372(Pt 3):799-809. PubMed ID: 12630911
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Domain interactions in the gelatinase A.TIMP-2.MT1-MMP activation complex. The ectodomain of the 44-kDa form of membrane type-1 matrix metalloproteinase does not modulate gelatinase A activation.
    Overall CM; Tam E; McQuibban GA; Morrison C; Wallon UM; Bigg HF; King AE; Roberts CR
    J Biol Chem; 2000 Dec; 275(50):39497-506. PubMed ID: 10991943
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The hemopexin domain of membrane-type matrix metalloproteinase-1 (MT1-MMP) Is not required for its activation of proMMP2 on cell surface but is essential for MT1-MMP-mediated invasion in three-dimensional type I collagen.
    Wang P; Nie J; Pei D
    J Biol Chem; 2004 Dec; 279(49):51148-55. PubMed ID: 15381707
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion.
    Itoh Y; Takamura A; Ito N; Maru Y; Sato H; Suenaga N; Aoki T; Seiki M
    EMBO J; 2001 Sep; 20(17):4782-93. PubMed ID: 11532942
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Competitive disruption of the tumor-promoting function of membrane type 1 matrix metalloproteinase/matrix metalloproteinase-14 in vivo.
    Nonaka T; Nishibashi K; Itoh Y; Yana I; Seiki M
    Mol Cancer Ther; 2005 Aug; 4(8):1157-66. PubMed ID: 16093431
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cellular activation of proMMP-13 by MT1-MMP depends on the C-terminal domain of MMP-13.
    Knäuper V; Bailey L; Worley JR; Soloway P; Patterson ML; Murphy G
    FEBS Lett; 2002 Dec; 532(1-2):127-30. PubMed ID: 12459476
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Internal cleavages of the autoinhibitory prodomain are required for membrane type 1 matrix metalloproteinase activation, although furin cleavage alone generates inactive proteinase.
    Golubkov VS; Cieplak P; Chekanov AV; Ratnikov BI; Aleshin AE; Golubkova NV; Postnova TI; Radichev IA; Rozanov DV; Zhu W; Motamedchaboki K; Strongin AY
    J Biol Chem; 2010 Sep; 285(36):27726-36. PubMed ID: 20605791
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proteolysis of the membrane type-1 matrix metalloproteinase prodomain: implications for a two-step proteolytic processing and activation.
    Golubkov VS; Chekanov AV; Shiryaev SA; Aleshin AE; Ratnikov BI; Gawlik K; Radichev I; Motamedchaboki K; Smith JW; Strongin AY
    J Biol Chem; 2007 Dec; 282(50):36283-91. PubMed ID: 17938169
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Analysis of tissue inhibitor of metalloproteinases-2 effect on pro-matrix metalloproteinase-2 activation by membrane-type 1 matrix metalloproteinase using baculovirus/insect-cell expression system.
    Jo Y; Yeon J; Kim HJ; Lee ST
    Biochem J; 2000 Feb; 345 Pt 3(Pt 3):511-9. PubMed ID: 10642509
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Plasmin activates pro-matrix metalloproteinase-2 with a membrane-type 1 matrix metalloproteinase-dependent mechanism.
    Monea S; Lehti K; Keski-Oja J; Mignatti P
    J Cell Physiol; 2002 Aug; 192(2):160-70. PubMed ID: 12115722
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Catalytic- and ecto-domains of membrane type 1-matrix metalloproteinase have similar inhibition profiles but distinct endopeptidase activities.
    Hurst DR; Schwartz MA; Ghaffari MA; Jin Y; Tschesche H; Fields GB; Sang QX
    Biochem J; 2004 Feb; 377(Pt 3):775-9. PubMed ID: 14533979
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CD44 binding through the hemopexin-like domain is critical for its shedding by membrane-type 1 matrix metalloproteinase.
    Suenaga N; Mori H; Itoh Y; Seiki M
    Oncogene; 2005 Jan; 24(5):859-68. PubMed ID: 15558018
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Claudin promotes activation of pro-matrix metalloproteinase-2 mediated by membrane-type matrix metalloproteinases.
    Miyamori H; Takino T; Kobayashi Y; Tokai H; Itoh Y; Seiki M; Sato H
    J Biol Chem; 2001 Jul; 276(30):28204-11. PubMed ID: 11382769
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Membrane type-1 matrix metalloproteinase functions as a proprotein self-convertase. Expression of the latent zymogen in Pichia pastoris, autolytic activation, and the peptide sequence of the cleavage forms.
    Rozanov DV; Strongin AY
    J Biol Chem; 2003 Mar; 278(10):8257-60. PubMed ID: 12514192
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tissue inhibitor of matrix metalloproteinase-2 regulates matrix metalloproteinase-2 activation by modulation of membrane-type 1 matrix metalloproteinase activity in high and low invasive melanoma cell lines.
    Kurschat P; Zigrino P; Nischt R; Breitkopf K; Steurer P; Klein CE; Krieg T; Mauch C
    J Biol Chem; 1999 Jul; 274(30):21056-62. PubMed ID: 10409657
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential inhibition of membrane type 3 (MT3)-matrix metalloproteinase (MMP) and MT1-MMP by tissue inhibitor of metalloproteinase (TIMP)-2 and TIMP-3 rgulates pro-MMP-2 activation.
    Zhao H; Bernardo MM; Osenkowski P; Sohail A; Pei D; Nagase H; Kashiwagi M; Soloway PD; DeClerck YA; Fridman R
    J Biol Chem; 2004 Mar; 279(10):8592-601. PubMed ID: 14681236
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.