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5. Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Glasser E; Maji D; Biancon G; Puthenpeedikakkal AMK; Cavender CE; Tebaldi T; Jenkins JL; Mathews DH; Halene S; Kielkopf CL Nucleic Acids Res; 2022 May; 50(9):5299-5312. PubMed ID: 35524551 [TBL] [Abstract][Full Text] [Related]
6. HNRNPA1 promotes recognition of splice site decoys by U2AF2 in vivo. Howard JM; Lin H; Wallace AJ; Kim G; Draper JM; Haeussler M; Katzman S; Toloue M; Liu Y; Sanford JR Genome Res; 2018 May; 28(5):689-698. PubMed ID: 29650551 [TBL] [Abstract][Full Text] [Related]
7. A splice site-sensing conformational switch in U2AF2 is modulated by U2AF1 and its recurrent myelodysplasia-associated mutation. Warnasooriya C; Feeney CF; Laird KM; Ermolenko DN; Kielkopf CL Nucleic Acids Res; 2020 Jun; 48(10):5695-5709. PubMed ID: 32343311 [TBL] [Abstract][Full Text] [Related]
8. In vitro iCLIP-based modeling uncovers how the splicing factor U2AF2 relies on regulation by cofactors. Sutandy FXR; Ebersberger S; Huang L; Busch A; Bach M; Kang HS; Fallmann J; Maticzka D; Backofen R; Stadler PF; Zarnack K; Sattler M; Legewie S; König J Genome Res; 2018 May; 28(5):699-713. PubMed ID: 29643205 [TBL] [Abstract][Full Text] [Related]
9. Monovalent Ionic Atmosphere Modulates the Selection of Suboptimal RNA Sequences by Splicing Factors' RNA Recognition Motifs. Rozza R; Janoš P; Magistrato A J Chem Inf Model; 2023 May; 63(10):3086-3093. PubMed ID: 37129986 [TBL] [Abstract][Full Text] [Related]
10. A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing. Galardi JW; Bela VN; Jeffery N; He X; Glasser E; Loerch S; Jenkins JL; Pulvino MJ; Boutz PL; Kielkopf CL J Biol Chem; 2022 Aug; 298(8):102224. PubMed ID: 35780835 [TBL] [Abstract][Full Text] [Related]
11. A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex. Chatrikhi R; Feeney CF; Pulvino MJ; Alachouzos G; MacRae AJ; Falls Z; Rai S; Brennessel WW; Jenkins JL; Walter MJ; Graubert TA; Samudrala R; Jurica MS; Frontier AJ; Kielkopf CL Cell Chem Biol; 2021 Aug; 28(8):1145-1157.e6. PubMed ID: 33689684 [TBL] [Abstract][Full Text] [Related]
12. An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2. Kang HS; Sánchez-Rico C; Ebersberger S; Sutandy FXR; Busch A; Welte T; Stehle R; Hipp C; Schulz L; Buchbender A; Zarnack K; König J; Sattler M Proc Natl Acad Sci U S A; 2020 Mar; 117(13):7140-7149. PubMed ID: 32188783 [TBL] [Abstract][Full Text] [Related]
16. Stuck on UUUU: New splicing inhibitors enhance U2AF2-RNA binding. Love SL; Hoskins AA Cell Chem Biol; 2021 Aug; 28(8):1106-1108. PubMed ID: 34416141 [TBL] [Abstract][Full Text] [Related]
17. Identification of a small molecule splicing inhibitor targeting UHM domains. Kobayashi A; Clément MJ; Craveur P; El Hage K; Salone JM; Bollot G; Pastré D; Maucuer A FEBS J; 2022 Feb; 289(3):682-698. PubMed ID: 34520118 [TBL] [Abstract][Full Text] [Related]
18. An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Agrawal AA; Salsi E; Chatrikhi R; Henderson S; Jenkins JL; Green MR; Ermolenko DN; Kielkopf CL Nat Commun; 2016 Mar; 7():10950. PubMed ID: 26952537 [TBL] [Abstract][Full Text] [Related]
19. A flexible RNA backbone within the polypyrimidine tract is required for U2AF65 binding and pre-mRNA splicing in vivo. Chen C; Zhao X; Kierzek R; Yu YT Mol Cell Biol; 2010 Sep; 30(17):4108-19. PubMed ID: 20606010 [TBL] [Abstract][Full Text] [Related]
20. SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns. Fukumura K; Yoshimoto R; Sperotto L; Kang HS; Hirose T; Inoue K; Sattler M; Mayeda A Nat Commun; 2021 Aug; 12(1):4910. PubMed ID: 34389706 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]