354 related articles for article (PubMed ID: 36041646)
1. Brequinar and dipyridamole in combination exhibits synergistic antiviral activity against SARS-CoV-2 in vitro: Rationale for a host-acting antiviral treatment strategy for COVID-19.
Demarest JF; Kienle M; Boytz R; Ayres M; Kim EJ; Patten JJ; Chung D; Gandhi V; Davey RA; Sykes DB; Shohdy N; Pottage JC; Kumar VS
Antiviral Res; 2022 Oct; 206():105403. PubMed ID: 36041646
[TBL] [Abstract][Full Text] [Related]
2. Classical swine fever virus non-structural protein 4A recruits dihydroorotate dehydrogenase to facilitate viral replication.
Zhao B-q; Chen J; Chen J-X; Cheng Y; Zhou J-f; Bai J-s; Mao D-y; Zhou B
J Virol; 2024 Jun; 98(6):e0049424. PubMed ID: 38757985
[TBL] [Abstract][Full Text] [Related]
3. IMU-838, a Developmental DHODH Inhibitor in Phase II for Autoimmune Disease, Shows Anti-SARS-CoV-2 and Broad-Spectrum Antiviral Efficacy In Vitro.
Hahn F; Wangen C; Häge S; Peter AS; Dobler G; Hurst B; Julander J; Fuchs J; Ruzsics Z; Überla K; Jäck HM; Ptak R; Muehler A; Gröppel M; Vitt D; Peelen E; Kohlhof H; Marschall M
Viruses; 2020 Dec; 12(12):. PubMed ID: 33291455
[TBL] [Abstract][Full Text] [Related]
4. A Broad Antiviral Strategy: Inhibitors of Human DHODH Pave the Way for Host-Targeting Antivirals against Emerging and Re-Emerging Viruses.
Zheng Y; Li S; Song K; Ye J; Li W; Zhong Y; Feng Z; Liang S; Cai Z; Xu K
Viruses; 2022 Apr; 14(5):. PubMed ID: 35632670
[TBL] [Abstract][Full Text] [Related]
5. Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2.
Xiong R; Zhang L; Li S; Sun Y; Ding M; Wang Y; Zhao Y; Wu Y; Shang W; Jiang X; Shan J; Shen Z; Tong Y; Xu L; Chen Y; Liu Y; Zou G; Lavillete D; Zhao Z; Wang R; Zhu L; Xiao G; Lan K; Li H; Xu K
Protein Cell; 2020 Oct; 11(10):723-739. PubMed ID: 32754890
[TBL] [Abstract][Full Text] [Related]
6. Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2.
Wagoner J; Herring S; Hsiang TY; Ianevski A; Biering SB; Xu S; Hoffmann M; Pöhlmann S; Gale M; Aittokallio T; Schiffer JT; White JM; Polyak SJ
Microbiol Spectr; 2022 Oct; 10(5):e0333122. PubMed ID: 36190406
[TBL] [Abstract][Full Text] [Related]
7. The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines.
Luban J; Sattler RA; Mühlberger E; Graci JD; Cao L; Weetall M; Trotta C; Colacino JM; Bavari S; Strambio-De-Castillia C; Suder EL; Wang Y; Soloveva V; Cintron-Lue K; Naryshkin NA; Pykett M; Welch EM; O'Keefe K; Kong R; Goodwin E; Jacobson A; Paessler S; Peltz SW
Virus Res; 2021 Jan; 292():198246. PubMed ID: 33249060
[TBL] [Abstract][Full Text] [Related]
8. Effective deploying of a novel DHODH inhibitor against herpes simplex type 1 and type 2 replication.
Luganini A; Sibille G; Mognetti B; Sainas S; Pippione AC; Giorgis M; Boschi D; Lolli ML; Gribaudo G
Antiviral Res; 2021 May; 189():105057. PubMed ID: 33716051
[TBL] [Abstract][Full Text] [Related]
9. Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses.
Luthra P; Naidoo J; Pietzsch CA; De S; Khadka S; Anantpadma M; Williams CG; Edwards MR; Davey RA; Bukreyev A; Ready JM; Basler CF
Antiviral Res; 2018 Oct; 158():288-302. PubMed ID: 30144461
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and Characterization of DHODH Inhibitors Based on the Vidofludimus Scaffold with Pronounced Anti-SARS-CoV-2 Activity.
Gege C; Hahn F; Wangen C; Häge S; Herrmann A; Uhlig N; Eberlein V; Issmail L; Klopfleisch R; Grunwald T; Marschall M; Kohlhof H; Vitt D
ChemMedChem; 2024 Jun; ():e202400292. PubMed ID: 38887198
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of dengue virus through suppression of host pyrimidine biosynthesis.
Wang QY; Bushell S; Qing M; Xu HY; Bonavia A; Nunes S; Zhou J; Poh MK; Florez de Sessions P; Niyomrattanakit P; Dong H; Hoffmaster K; Goh A; Nilar S; Schul W; Jones S; Kramer L; Compton T; Shi PY
J Virol; 2011 Jul; 85(13):6548-56. PubMed ID: 21507975
[TBL] [Abstract][Full Text] [Related]
12. A comprehensive drug repurposing study for COVID19 treatment: novel putative dihydroorotate dehydrogenase inhibitors show association to serotonin-dopamine receptors.
Berber B; Doluca O
Brief Bioinform; 2021 Mar; 22(2):1023-1037. PubMed ID: 33406218
[TBL] [Abstract][Full Text] [Related]
13. The FDA-Approved Drug Cobicistat Synergizes with Remdesivir To Inhibit SARS-CoV-2 Replication
Shytaj IL; Fares M; Gallucci L; Lucic B; Tolba MM; Zimmermann L; Adler JM; Xing N; Bushe J; Gruber AD; Ambiel I; Taha Ayoub A; Cortese M; Neufeldt CJ; Stolp B; Sobhy MH; Fathy M; Zhao M; Laketa V; Diaz RS; Sutton RE; Chlanda P; Boulant S; Bartenschlager R; Stanifer ML; Fackler OT; Trimpert J; Savarino A; Lusic M
mBio; 2022 Apr; 13(2):e0370521. PubMed ID: 35229634
[TBL] [Abstract][Full Text] [Related]
14. TMPRSS2 and RNA-Dependent RNA Polymerase Are Effective Targets of Therapeutic Intervention for Treatment of COVID-19 Caused by SARS-CoV-2 Variants (B.1.1.7 and B.1.351).
Lee J; Lee J; Kim HJ; Ko M; Jee Y; Kim S
Microbiol Spectr; 2021 Sep; 9(1):e0047221. PubMed ID: 34378968
[TBL] [Abstract][Full Text] [Related]
15. The Novel
Sibille G; Luganini A; Sainas S; Boschi D; Lolli ML; Gribaudo G
Viruses; 2022 Oct; 14(10):. PubMed ID: 36298835
[TBL] [Abstract][Full Text] [Related]
16. JIB-04 Has Broad-Spectrum Antiviral Activity and Inhibits SARS-CoV-2 Replication and Coronavirus Pathogenesis.
Son J; Huang S; Zeng Q; Bricker TL; Case JB; Zhou J; Zang R; Liu Z; Chang X; Darling TL; Xu J; Harastani HH; Chen L; Gomez Castro MF; Zhao Y; Kohio HP; Hou G; Fan B; Niu B; Guo R; Rothlauf PW; Bailey AL; Wang X; Shi PY; Martinez ED; Brody SL; Whelan SPJ; Diamond MS; Boon ACM; Li B; Ding S
mBio; 2022 Feb; 13(1):e0337721. PubMed ID: 35038906
[TBL] [Abstract][Full Text] [Related]
17. Antiviral Activity of Type I, II, and III Interferons Counterbalances ACE2 Inducibility and Restricts SARS-CoV-2.
Busnadiego I; Fernbach S; Pohl MO; Karakus U; Huber M; Trkola A; Stertz S; Hale BG
mBio; 2020 Sep; 11(5):. PubMed ID: 32913009
[TBL] [Abstract][Full Text] [Related]
18. SARS-CoV-2 couples evasion of inflammatory response to activated nucleotide synthesis.
Qin C; Rao Y; Yuan H; Wang TY; Zhao J; Espinosa B; Liu Y; Zhang S; Savas AC; Liu Q; Zarinfar M; Rice S; Henley J; Comai L; Graham NA; Chen C; Zhang C; Feng P
Proc Natl Acad Sci U S A; 2022 Jun; 119(26):e2122897119. PubMed ID: 35700355
[TBL] [Abstract][Full Text] [Related]
19. Stenoparib, an Inhibitor of Cellular Poly(ADP-Ribose) Polymerase, Blocks Replication of the SARS-CoV-2 and HCoV-NL63 Human Coronaviruses
Stone NE; Jaramillo SA; Jones AN; Vazquez AJ; Martz M; Versluis LM; Raniere MO; Nunnally HE; Zarn KE; Nottingham R; Ng KR; Sahl JW; Wagner DM; Knudsen S; Settles EW; Keim P; French CT
mBio; 2021 Jan; 12(1):. PubMed ID: 33468703
[TBL] [Abstract][Full Text] [Related]
20. Antiviral activity of brequinar against African swine fever virus infection in vitro.
Grigoryan R; Arabyan E; Izmailyan R; Karalyan Z; Jordão N; Ferreira F; Zakaryan H
Virus Res; 2022 Aug; 317():198826. PubMed ID: 35618075
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
