BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 36043494)

  • 21. 2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol inhibits MDM2 and induces apoptosis in breast cancer cells through a p53-independent pathway.
    Xu J; Han M; Shen J; Guan Q; Bai Z; Lang B; Zhang H; Li Z; Zuo D; Zhang W; Wu Y
    Cancer Lett; 2016 Dec; 383(1):9-17. PubMed ID: 27693458
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Spiro-oxindole derivative 5-chloro-4',5'-diphenyl-3'-(4-(2-(piperidin-1-yl) ethoxy) benzoyl) spiro[indoline-3,2'-pyrrolidin]-2-one triggers apoptosis in breast cancer cells via restoration of p53 function.
    Saxena R; Gupta G; Manohar M; Debnath U; Popli P; Prabhakar YS; Konwar R; Kumar S; Kumar A; Dwivedi A
    Int J Biochem Cell Biol; 2016 Jan; 70():105-17. PubMed ID: 26556313
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Mdm2 promotes Cdc25C protein degradation and delays cell cycle progression through the G2/M phase.
    Giono LE; Resnick-Silverman L; Carvajal LA; St Clair S; Manfredi JJ
    Oncogene; 2017 Dec; 36(49):6762-6773. PubMed ID: 28806397
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Oridonin induces Mdm2-p60 to promote p53-mediated apoptosis and cell cycle arrest in neuroblastoma.
    Zhu HQ; Zhang C; Guo ZY; Yang JM; Guo JH; Chen C; Yao QH; Liu F; Zhang QW; Gao FH
    Cancer Med; 2019 Sep; 8(11):5313-5326. PubMed ID: 31339234
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Mutant p53 Sequestration of the MDM2 Acidic Domain Inhibits E3 Ligase Activity.
    Yang L; Song T; Cheng Q; Chen L; Chen J
    Mol Cell Biol; 2019 Feb; 39(4):. PubMed ID: 30455251
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Ret finger protein 2 enhances ionizing radiation-induced apoptosis via degradation of AKT and MDM2.
    Joo HM; Kim JY; Jeong JB; Seong KM; Nam SY; Yang KH; Kim CS; Kim HS; Jeong M; An S; Jin YW
    Eur J Cell Biol; 2011 May; 90(5):420-31. PubMed ID: 21333377
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The role of miR-18b in MDM2-p53 pathway signaling and melanoma progression.
    Dar AA; Majid S; Rittsteuer C; de Semir D; Bezrookove V; Tong S; Nosrati M; Sagebiel R; Miller JR; Kashani-Sabet M
    J Natl Cancer Inst; 2013 Mar; 105(6):433-42. PubMed ID: 23365201
    [TBL] [Abstract][Full Text] [Related]  

  • 28. p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug.
    Wang SP; Wang WL; Chang YL; Wu CT; Chao YC; Kao SH; Yuan A; Lin CW; Yang SC; Chan WK; Li KC; Hong TM; Yang PC
    Nat Cell Biol; 2009 Jun; 11(6):694-704. PubMed ID: 19448627
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Enigma negatively regulates p53 through MDM2 and promotes tumor cell survival in mice.
    Jung CR; Lim JH; Choi Y; Kim DG; Kang KJ; Noh SM; Im DS
    J Clin Invest; 2010 Dec; 120(12):4493-506. PubMed ID: 21060154
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Regulation of p53: a collaboration between Mdm2 and Mdmx.
    Pei D; Zhang Y; Zheng J
    Oncotarget; 2012 Mar; 3(3):228-35. PubMed ID: 22410433
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase.
    Okamoto K; Taya Y; Nakagama H
    FEBS Lett; 2009 Sep; 583(17):2710-4. PubMed ID: 19619542
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Smad ubiquitylation regulatory factor 1/2 (Smurf1/2) promotes p53 degradation by stabilizing the E3 ligase MDM2.
    Nie J; Xie P; Liu L; Xing G; Chang Z; Yin Y; Tian C; He F; Zhang L
    J Biol Chem; 2010 Jul; 285(30):22818-30. PubMed ID: 20484049
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A second p53 binding site in the central domain of Mdm2 is essential for p53 ubiquitination.
    Ma J; Martin JD; Zhang H; Auger KR; Ho TF; Kirkpatrick RB; Grooms MH; Johanson KO; Tummino PJ; Copeland RA; Lai Z
    Biochemistry; 2006 Aug; 45(30):9238-45. PubMed ID: 16866370
    [TBL] [Abstract][Full Text] [Related]  

  • 34. MDM2 acts downstream of p53 as an E3 ligase to promote FOXO ubiquitination and degradation.
    Fu W; Ma Q; Chen L; Li P; Zhang M; Ramamoorthy S; Nawaz Z; Shimojima T; Wang H; Yang Y; Shen Z; Zhang Y; Zhang X; Nicosia SV; Zhang Y; Pledger JW; Chen J; Bai W
    J Biol Chem; 2009 May; 284(21):13987-4000. PubMed ID: 19321440
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Regulation of Mdm2 protein stability and the p53 response by NEDD4-1 E3 ligase.
    Xu C; Fan CD; Wang X
    Oncogene; 2015 Jan; 34(3):281-9. PubMed ID: 24413081
    [TBL] [Abstract][Full Text] [Related]  

  • 36. TRIAD1 inhibits MDM2-mediated p53 ubiquitination and degradation.
    Bae S; Jung JH; Kim K; An IS; Kim SY; Lee JH; Park IC; Jin YW; Lee SJ; An S
    FEBS Lett; 2012 Sep; 586(19):3057-63. PubMed ID: 22819825
    [TBL] [Abstract][Full Text] [Related]  

  • 37. SUMO-specific protease SUSP4 positively regulates p53 by promoting Mdm2 self-ubiquitination.
    Lee MH; Lee SW; Lee EJ; Choi SJ; Chung SS; Lee JI; Cho JM; Seol JH; Baek SH; Kim KI; Chiba T; Tanaka K; Bang OS; Chung CH
    Nat Cell Biol; 2006 Dec; 8(12):1424-31. PubMed ID: 17086174
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Aciculatin induces p53-dependent apoptosis via MDM2 depletion in human cancer cells in vitro and in vivo.
    Lai CY; Tsai AC; Chen MC; Chang LH; Sun HL; Chang YL; Chen CC; Teng CM; Pan SL
    PLoS One; 2012; 7(8):e42192. PubMed ID: 22912688
    [TBL] [Abstract][Full Text] [Related]  

  • 39. MDM2 Inhibits Axin-Induced p53 Activation Independently of its E3 Ligase Activity.
    He Y; Lian G; Lin S; Ye Z; Li Q
    PLoS One; 2013; 8(6):e67529. PubMed ID: 23826318
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation.
    Lindström MS; Jin A; Deisenroth C; White Wolf G; Zhang Y
    Mol Cell Biol; 2007 Feb; 27(3):1056-68. PubMed ID: 17116689
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.