BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

350 related articles for article (PubMed ID: 36046356)

  • 1. Targeting the two-pore channel 2 in cancer progression and metastasis.
    Skelding KA; Barry DL; Theron DZ; Lincz LF
    Explor Target Antitumor Ther; 2022; 3(1):62-89. PubMed ID: 36046356
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Endolysosomal two-pore channels regulate autophagy in cardiomyocytes.
    García-Rúa V; Feijóo-Bandín S; Rodríguez-Penas D; Mosquera-Leal A; Abu-Assi E; Beiras A; María Seoane L; Lear P; Parrington J; Portolés M; Roselló-Lletí E; Rivera M; Gualillo O; Parra V; Hill JA; Rothermel B; González-Juanatey JR; Lago F
    J Physiol; 2016 Jun; 594(11):3061-77. PubMed ID: 26757341
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Endolysosomal Cation Channels and Cancer-A Link with Great Potential.
    Grimm C; Bartel K; Vollmar AM; Biel M
    Pharmaceuticals (Basel); 2018 Jan; 11(1):. PubMed ID: 29303993
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Naringenin Impairs Two-Pore Channel 2 Activity And Inhibits VEGF-Induced Angiogenesis.
    Pafumi I; Festa M; Papacci F; Lagostena L; Giunta C; Gutla V; Cornara L; Favia A; Palombi F; Gambale F; Filippini A; Carpaneto A
    Sci Rep; 2017 Jul; 7(1):5121. PubMed ID: 28698624
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth.
    Müller M; Gerndt S; Chao YK; Zisis T; Nguyen ONP; Gerwien A; Urban N; Müller C; Gegenfurtner FA; Geisslinger F; Ortler C; Chen CC; Zahler S; Biel M; Schaefer M; Grimm C; Bracher F; Vollmar AM; Bartel K
    Cell Chem Biol; 2021 Aug; 28(8):1119-1131.e27. PubMed ID: 33626324
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Endolysosomal Ca
    Alharbi AF; Parrington J
    Front Cell Dev Biol; 2019; 7():302. PubMed ID: 31867325
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis for inhibition of the lysosomal two-pore channel TPC2 by a small molecule antagonist.
    Chi G; Jaślan D; Kudrina V; Böck J; Li H; Pike ACW; Rautenberg S; Krogsaeter E; Bohstedt T; Wang D; McKinley G; Fernandez-Cid A; Mukhopadhyay SMM; Burgess-Brown NA; Keller M; Bracher F; Grimm C; Dürr KL
    Structure; 2024 May; ():. PubMed ID: 38815576
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Endolysosomal two-pore channel 2 plays opposing roles in primary and metastatic malignant melanoma cells.
    Barbonari S; D'Amore A; Hanbashi AA; Palombi F; Riccioli A; Parrington J; Filippini A
    Cell Biol Int; 2024 Apr; 48(4):521-540. PubMed ID: 38263578
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Endolysosomal Ca
    Faris P; Shekha M; Montagna D; Guerra G; Moccia F
    Cancers (Basel); 2018 Dec; 11(1):. PubMed ID: 30591696
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TPC2 polymorphisms associated with a hair pigmentation phenotype in humans result in gain of channel function by independent mechanisms.
    Chao YK; Schludi V; Chen CC; Butz E; Nguyen ONP; Müller M; Krüger J; Kammerbauer C; Ben-Johny M; Vollmar AM; Berking C; Biel M; Wahl-Schott CA; Grimm C
    Proc Natl Acad Sci U S A; 2017 Oct; 114(41):E8595-E8602. PubMed ID: 28923947
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation.
    Lin-Moshier Y; Keebler MV; Hooper R; Boulware MJ; Liu X; Churamani D; Abood ME; Walseth TF; Brailoiu E; Patel S; Marchant JS
    Proc Natl Acad Sci U S A; 2014 Sep; 111(36):13087-92. PubMed ID: 25157141
    [TBL] [Abstract][Full Text] [Related]  

  • 12. mTORC1 controls lysosomal Ca
    Ogunbayo OA; Duan J; Xiong J; Wang Q; Feng X; Ma J; Zhu MX; Evans AM
    Sci Signal; 2018 Apr; 11(525):. PubMed ID: 29636391
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels.
    Yamaguchi S; Jha A; Li Q; Soyombo AA; Dickinson GD; Churamani D; Brailoiu E; Patel S; Muallem S
    J Biol Chem; 2011 Jul; 286(26):22934-42. PubMed ID: 21540176
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting TPC2 sensitizes acute lymphoblastic leukemia cells to chemotherapeutics by impairing lysosomal function.
    Geisslinger F; Müller M; Chao YK; Grimm C; Vollmar AM; Bartel K
    Cell Death Dis; 2022 Aug; 13(8):668. PubMed ID: 35915060
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lysosomal two-pore channel subtype 2 (TPC2) regulates skeletal muscle autophagic signaling.
    Lin PH; Duann P; Komazaki S; Park KH; Li H; Sun M; Sermersheim M; Gumpper K; Parrington J; Galione A; Evans AM; Zhu MX; Ma J
    J Biol Chem; 2015 Feb; 290(6):3377-89. PubMed ID: 25480788
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A Role for Two-Pore Channel Type 2 (TPC2)-Mediated Regulation of Membrane Contact Sites During Zebrafish Notochord Biogenesis?
    Rice KL; Chan CM; Kelu JJ; Miller AL; Webb SE
    Contact (Thousand Oaks); 2023; 6():25152564231211409. PubMed ID: 38028019
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of potassium and calcium channel inhibitors as modulators of polyomavirus endosomal trafficking.
    Dobson SJ; Mankouri J; Whitehouse A
    Antiviral Res; 2020 Jul; 179():104819. PubMed ID: 32389733
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ca
    Kelu JJ; Webb SE; Parrington J; Galione A; Miller AL
    Dev Biol; 2017 May; 425(2):109-129. PubMed ID: 28390800
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TPC2 controls pigmentation by regulating melanosome pH and size.
    Ambrosio AL; Boyle JA; Aradi AE; Christian KA; Di Pietro SM
    Proc Natl Acad Sci U S A; 2016 May; 113(20):5622-7. PubMed ID: 27140606
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Endolysosomal Cation Channels and MITF in Melanocytes and Melanoma.
    Abrahamian C; Grimm C
    Biomolecules; 2021 Jul; 11(7):. PubMed ID: 34356645
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.