131 related articles for article (PubMed ID: 36047190)
21. Increased FasL expression correlates with apoptotic changes in granulocytes cultured with oxidized clozapine.
Husain Z; Almeciga I; Delgado JC; Clavijo OP; Castro JE; Belalcazar V; Pinto C; Zuñiga J; Romero V; Yunis EJ
Toxicol Appl Pharmacol; 2006 Aug; 214(3):326-34. PubMed ID: 16510162
[TBL] [Abstract][Full Text] [Related]
22. Metabolism of clozapine by human neutrophils: evidence for a specific oxidation of clozapine by the myeloperoxidase system with inhibition of enzymatic chlorination cycle.
Frimat B; Gressier B; Odou P; Brunet C; Dine T; Luycky M; Cazin M; Cazin JC
Fundam Clin Pharmacol; 1997; 11(3):267-74. PubMed ID: 9243259
[TBL] [Abstract][Full Text] [Related]
23. Role of human glutathione S-transferases in the inactivation of reactive metabolites of clozapine.
Dragovic S; Boerma JS; van Bergen L; Vermeulen NP; Commandeur JN
Chem Res Toxicol; 2010 Sep; 23(9):1467-76. PubMed ID: 20849150
[TBL] [Abstract][Full Text] [Related]
24. Bioactivation and covalent binding of hydroxyfluperlapine in human neutrophils: implications for fluperlapine-induced agranulocytosis.
Lai WG; Gardner I; Zahid N; Uetrecht JP
Drug Metab Dispos; 2000 Mar; 28(3):255-63. PubMed ID: 10681368
[TBL] [Abstract][Full Text] [Related]
25. Comparative oxidation of loxapine and clozapine by human neutrophils.
Jegouzo A; Gressier B; Frimat B; Brunet C; Dine T; Luyckx M; Kouach M; Cazin M; Cazin JC
Fundam Clin Pharmacol; 1999; 13(1):113-9. PubMed ID: 10027097
[TBL] [Abstract][Full Text] [Related]
26. Investigation of Clozapine and Olanzapine Reactive Metabolite Formation and Protein Binding by Liquid Chromatography-Tandem Mass Spectrometry.
Geib T; Thulasingam M; Haeggström JZ; Sleno L
Chem Res Toxicol; 2020 Sep; 33(9):2420-2431. PubMed ID: 32786547
[TBL] [Abstract][Full Text] [Related]
27. [Antipsychotics in bipolar disorders].
Vacheron-Trystram MN; Braitman A; Cheref S; Auffray L
Encephale; 2004; 30(5):417-24. PubMed ID: 15627046
[TBL] [Abstract][Full Text] [Related]
28. Bioactivation of clozapine by murine cardiac tissue in vivo and in vitro.
Williams DP; O'Donnell CJ; Maggs JL; Leeder JS; Uetrecht J; Pirmohamed M; Park BK
Chem Res Toxicol; 2003 Oct; 16(10):1359-64. PubMed ID: 14565776
[TBL] [Abstract][Full Text] [Related]
29. Clozapine is oxidized by activated human neutrophils to a reactive nitrenium ion that irreversibly binds to the cells.
Liu ZC; Uetrecht JP
J Pharmacol Exp Ther; 1995 Dec; 275(3):1476-83. PubMed ID: 8531118
[TBL] [Abstract][Full Text] [Related]
30. Reactive metabolites and agranulocytosis.
Uetrecht JP
Eur J Haematol Suppl; 1996; 60():83-8. PubMed ID: 8987247
[TBL] [Abstract][Full Text] [Related]
31. Neutrophil Myeloperoxidase-Mediated N-Demethylation of Quetiapine Leads to
Rashid MH; Babu D; Tran N; Reiz B; Siraki AG
Chem Res Toxicol; 2022 Jun; 35(6):1001-1010. PubMed ID: 35575633
[TBL] [Abstract][Full Text] [Related]
32. Thymoquinone reduces mitochondrial damage and death of cardiomyocytes induced by clozapine.
Hafez AA; Jamali Z; Khezri S; Salimi A
Naunyn Schmiedebergs Arch Pharmacol; 2021 Aug; 394(8):1675-1684. PubMed ID: 33937934
[TBL] [Abstract][Full Text] [Related]
33. Characterization of human cytochrome P450s involved in the bioactivation of clozapine.
Dragovic S; Gunness P; Ingelman-Sundberg M; Vermeulen NP; Commandeur JN
Drug Metab Dispos; 2013 Mar; 41(3):651-8. PubMed ID: 23297297
[TBL] [Abstract][Full Text] [Related]
34. Clozapine-induced agranulocytosis/granulocytopenia: mechanisms and monitoring.
Wiciński M; Węclewicz MM
Curr Opin Hematol; 2018 Jan; 25(1):22-28. PubMed ID: 28984748
[TBL] [Abstract][Full Text] [Related]
35. Examination of possible toxic and immune mechanisms of clozapine-induced agranulocytosis.
Guest I; Sokoluk B; MacCrimmon J; Uetrecht J
Toxicology; 1998 Nov; 131(1):53-65. PubMed ID: 9881934
[TBL] [Abstract][Full Text] [Related]
36. Role of Oxidative Stress and Reactive Metabolites in Cytotoxicity & Mitotoxicity of Clozapine, Diclofenac and Nifedipine in CHO-K1 Cells In Vitro.
Ergüç A; Karakuş F; Arzuk E; Mutlu N; Orhan H
Endocr Metab Immune Disord Drug Targets; 2023 Apr; ():. PubMed ID: 37114786
[TBL] [Abstract][Full Text] [Related]
37. Y-931, a novel atypical antipsychotic drug, is less sensitive to oxidative phenomena.
Kohara T; Koyama T; Fujimura M; Tanaka H; Maeda J; Fujimoto T; Yamamoto I; Arita M
Chem Pharm Bull (Tokyo); 2002 Jun; 50(6):818-21. PubMed ID: 12045338
[TBL] [Abstract][Full Text] [Related]
38. Uptake of clozapine into HL-60 promyelocytic leukaemia cells.
Henning U; Löffler S; Krieger K; Klimke A
Pharmacopsychiatry; 2002 May; 35(3):90-5. PubMed ID: 12107852
[TBL] [Abstract][Full Text] [Related]
39. Exploring off-targets and off-systems for adverse drug reactions via chemical-protein interactome--clozapine-induced agranulocytosis as a case study.
Yang L; Wang K; Chen J; Jegga AG; Luo H; Shi L; Wan C; Guo X; Qin S; He G; Feng G; He L
PLoS Comput Biol; 2011 Mar; 7(3):e1002016. PubMed ID: 21483481
[TBL] [Abstract][Full Text] [Related]
40. The role of oxidative stress in antipsychotics induced ovarian toxicity.
Elmorsy E; Al-Ghafari A; Aggour AM; Khan R; Amer S
Toxicol In Vitro; 2017 Oct; 44():190-195. PubMed ID: 28712880
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
