BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 36049535)

  • 1. Neuroprotection of resveratrol against cadmium-poisoning acts through dual inhibition of mTORC1/2 signaling.
    Liu C; Zhang R; Yang L; Ji T; Zhu C; Liu B; Zhang H; Xu C; Zhang N; Huang S; Chen L
    Neuropharmacology; 2022 Nov; 219():109236. PubMed ID: 36049535
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rapamycin prevents cadmium-induced neuronal cell death via targeting both mTORC1 and mTORC2 pathways.
    Xu C; Liu C; Liu L; Zhang R; Zhang H; Chen S; Luo Y; Chen L; Huang S
    Neuropharmacology; 2015 Oct; 97():35-45. PubMed ID: 26002629
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells.
    Zeng Q; Qin S; Zhang H; Liu B; Qin J; Wang X; Zhang R; Liu C; Dong X; Zhang S; Huang S; Chen L
    J Cell Physiol; 2018 Jan; 233(1):516-529. PubMed ID: 28300280
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Resveratrol prevents cadmium activation of Erk1/2 and JNK pathways from neuronal cell death via protein phosphatases 2A and 5.
    Liu C; Zhang R; Sun C; Zhang H; Xu C; Liu W; Gao W; Huang S; Chen L
    J Neurochem; 2015 Nov; 135(3):466-78. PubMed ID: 26146868
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Resveratrol inhibits Erk1/2-mediated adhesion of cancer cells via activating PP2A-PTEN signaling network.
    Chen X; Hu X; Li Y; Zhu C; Dong X; Zhang R; Ma J; Huang S; Chen L
    J Cell Physiol; 2019 Mar; 234(3):2822-2836. PubMed ID: 30066962
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson's disease.
    Xu Y; Liu C; Chen S; Ye Y; Guo M; Ren Q; Liu L; Zhang H; Xu C; Zhou Q; Huang S; Chen L
    Cell Signal; 2014 Aug; 26(8):1680-1689. PubMed ID: 24726895
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanistic Target of Rapamycin Complex 1 (mTORC1) and mTORC2 as Key Signaling Intermediates in Mesenchymal Cell Activation.
    Walker NM; Belloli EA; Stuckey L; Chan KM; Lin J; Lynch W; Chang A; Mazzoni SM; Fingar DC; Lama VN
    J Biol Chem; 2016 Mar; 291(12):6262-71. PubMed ID: 26755732
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion.
    Chen L; Xu B; Liu L; Liu C; Luo Y; Chen X; Barzegar M; Chung J; Huang S
    Oncotarget; 2015 Mar; 6(9):7136-50. PubMed ID: 25762619
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rapamycin ameliorates cadmium-induced activation of MAPK pathway and neuronal apoptosis by preventing mitochondrial ROS inactivation of PP2A.
    Xu C; Wang X; Zhu Y; Dong X; Liu C; Zhang H; Liu L; Huang S; Chen L
    Neuropharmacology; 2016 Jun; 105():270-284. PubMed ID: 26805420
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Celastrol Attenuates Cadmium-Induced Neuronal Apoptosis via Inhibiting Ca
    Zhang R; Zhu Y; Dong X; Liu B; Zhang N; Wang X; Liu L; Xu C; Huang S; Chen L
    J Cell Physiol; 2017 Aug; 232(8):2145-2157. PubMed ID: 27891586
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
    Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
    Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network.
    Chen S; Gu C; Xu C; Zhang J; Xu Y; Ren Q; Guo M; Huang S; Chen L
    J Neurochem; 2014 Jan; 128(2):256-266. PubMed ID: 24111524
    [TBL] [Abstract][Full Text] [Related]  

  • 13. AKT inhibition overcomes rapamycin resistance by enhancing the repressive function of PRAS40 on mTORC1/4E-BP1 axis.
    Mi W; Ye Q; Liu S; She QB
    Oncotarget; 2015 Jun; 6(16):13962-77. PubMed ID: 25961827
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metformin attenuates cadmium-induced neuronal apoptosis in vitro via blocking ROS-dependent PP5/AMPK-JNK signaling pathway.
    Chen X; Wu W; Gong B; Hou L; Dong X; Xu C; Zhao R; Yu Q; Zhou Z; Huang S; Chen L
    Neuropharmacology; 2020 Sep; 175():108065. PubMed ID: 32209321
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Celastrol ameliorates Cd-induced neuronal apoptosis by targeting NOX2-derived ROS-dependent PP5-JNK signaling pathway.
    Xu C; Wang X; Gu C; Zhang H; Zhang R; Dong X; Liu C; Hu X; Ji X; Huang S; Chen L
    J Neurochem; 2017 Apr; 141(1):48-62. PubMed ID: 28129433
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rapamycin inhibits Erk1/2-mediated neuronal apoptosis caused by cadmium.
    Xu C; Zhang H; Liu C; Zhu Y; Wang X; Gao W; Huang S; Chen L
    Oncotarget; 2015 Aug; 6(25):21452-67. PubMed ID: 26046303
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nobiletin prevents cadmium-induced neuronal apoptosis by inhibiting reactive oxygen species and modulating JNK/ERK1/2 and Akt/mTOR networks in rats.
    Qu Y; Liu Y; Chen L; Zhu Y; Xiao X; Wang D; Zhu Y
    Neurol Res; 2018 Mar; 40(3):211-220. PubMed ID: 29334873
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity.
    Liu L; Luo Y; Chen L; Shen T; Xu B; Chen W; Zhou H; Han X; Huang S
    J Biol Chem; 2010 Dec; 285(49):38362-73. PubMed ID: 20937815
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cadmium Activates Reactive Oxygen Species-dependent AKT/mTOR and Mitochondrial Apoptotic Pathways in Neuronal Cells.
    Yuan Y; Wang Y; Hu FF; Jiang CY; Zhang YJ; Yang JL; Zhao SW; Gu JH; Liu XZ; Bian JC; Liu ZP
    Biomed Environ Sci; 2016 Feb; 29(2):117-26. PubMed ID: 27003169
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selective interference of mTORC1/RAPTOR protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism with Akt and autophagy induction.
    Ito M; Yurube T; Kakutani K; Maeno K; Takada T; Terashima Y; Kakiuchi Y; Takeoka Y; Miyazaki S; Kuroda R; Nishida K
    Osteoarthritis Cartilage; 2017 Dec; 25(12):2134-2146. PubMed ID: 28888905
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.