223 related articles for article (PubMed ID: 36051457)
1. Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity.
Choudhury S; Huang AY; Kim J; Zhou Z; Morillo K; Maury EA; Tsai JW; Miller MB; Lodato MA; Araten S; Hilal N; Lee EA; Chen MH; Walsh CA
Nat Aging; 2022 Aug; 2(8):714-725. PubMed ID: 36051457
[TBL] [Abstract][Full Text] [Related]
2. Landscape of somatic mutations in aging human heart muscle cells.
Walsh C; Choudhury S; Chen MH
Nat Aging; 2022 Aug; 2(8):686-687. PubMed ID: 36471785
[TBL] [Abstract][Full Text] [Related]
3. Single-neuron whole genome sequencing identifies increased somatic mutation burden in Alzheimer's disease related genes.
Li Z; Min S; Alliey-Rodriguez N; Giase G; Cheng L; Craig DW; Faulkner GJ; Asif H; Liu C; Gershon ES
Neurobiol Aging; 2023 Mar; 123():222-232. PubMed ID: 36599749
[TBL] [Abstract][Full Text] [Related]
4. Contrasting somatic mutation patterns in aging human neurons and oligodendrocytes.
Ganz J; Luquette LJ; Bizzotto S; Miller MB; Zhou Z; Bohrson CL; Jin H; Tran AV; Viswanadham VV; McDonough G; Brown K; Chahine Y; Chhouk B; Galor A; Park PJ; Walsh CA
Cell; 2024 Apr; 187(8):1955-1970.e23. PubMed ID: 38503282
[TBL] [Abstract][Full Text] [Related]
5. Somatic genomic changes in single Alzheimer's disease neurons.
Miller MB; Huang AY; Kim J; Zhou Z; Kirkham SL; Maury EA; Ziegenfuss JS; Reed HC; Neil JE; Rento L; Ryu SC; Ma CC; Luquette LJ; Ames HM; Oakley DH; Frosch MP; Hyman BT; Lodato MA; Lee EA; Walsh CA
Nature; 2022 Apr; 604(7907):714-722. PubMed ID: 35444284
[TBL] [Abstract][Full Text] [Related]
6. Contrasting patterns of somatic mutations in neurons and glia reveal differential predisposition to disease in the aging human brain.
Ganz J; Luquette LJ; Bizzotto S; Bohrson CL; Jin H; Miller MB; Zhou Z; Galor A; Park PJ; Walsh CA
bioRxiv; 2023 Jan; ():. PubMed ID: 36711756
[TBL] [Abstract][Full Text] [Related]
7. Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan.
Zhang L; Dong X; Lee M; Maslov AY; Wang T; Vijg J
Proc Natl Acad Sci U S A; 2019 Apr; 116(18):9014-9019. PubMed ID: 30992375
[TBL] [Abstract][Full Text] [Related]
8. Ultra-sensitive sequencing reveals an age-related increase in somatic mitochondrial mutations that are inconsistent with oxidative damage.
Kennedy SR; Salk JJ; Schmitt MW; Loeb LA
PLoS Genet; 2013; 9(9):e1003794. PubMed ID: 24086148
[TBL] [Abstract][Full Text] [Related]
9. Aging and neurodegeneration are associated with increased mutations in single human neurons.
Lodato MA; Rodin RE; Bohrson CL; Coulter ME; Barton AR; Kwon M; Sherman MA; Vitzthum CM; Luquette LJ; Yandava CN; Yang P; Chittenden TW; Hatem NE; Ryu SC; Woodworth MB; Park PJ; Walsh CA
Science; 2018 Feb; 359(6375):555-559. PubMed ID: 29217584
[TBL] [Abstract][Full Text] [Related]
10. Somatic mutations in the brain: relationship to aging?
Evans DA; Burbach JP; van Leeuwen FW
Mutat Res; 1995 Oct; 338(1-6):173-82. PubMed ID: 7565872
[TBL] [Abstract][Full Text] [Related]
11. Oxidative mutagenesis, mismatch repair, and aging.
Skinner AM; Turker MS
Sci Aging Knowledge Environ; 2005 Mar; 2005(9):re3. PubMed ID: 15744047
[TBL] [Abstract][Full Text] [Related]
12. Somatic mutation load and spectra: A record of DNA damage and repair in healthy human cells.
Saini N; Gordenin DA
Environ Mol Mutagen; 2018 Oct; 59(8):672-686. PubMed ID: 30152078
[TBL] [Abstract][Full Text] [Related]
13. DNA repair in cardiomyocytes is critical for maintaining cardiac function in mice.
de Boer M; Te Lintel Hekkert M; Chang J; van Thiel BS; Martens L; Bos MM; de Kleijnen MGJ; Ridwan Y; Octavia Y; van Deel ED; Blonden LA; Brandt RMC; Barnhoorn S; Bautista-Niño PK; Krabbendam-Peters I; Wolswinkel R; Arshi B; Ghanbari M; Kupatt C; de Windt LJ; Danser AHJ; van der Pluijm I; Remme CA; Stoll M; Pothof J; Roks AJM; Kavousi M; Essers J; van der Velden J; Hoeijmakers JHJ; Duncker DJ
Aging Cell; 2023 Mar; 22(3):e13768. PubMed ID: 36756698
[TBL] [Abstract][Full Text] [Related]
14. Oxidative stress is not a major contributor to somatic mitochondrial DNA mutations.
Itsara LS; Kennedy SR; Fox EJ; Yu S; Hewitt JJ; Sanchez-Contreras M; Cardozo-Pelaez F; Pallanck LJ
PLoS Genet; 2014 Feb; 10(2):e1003974. PubMed ID: 24516391
[TBL] [Abstract][Full Text] [Related]
15. Aging affects the levels of DNA damage in postmitotic cells.
Gaubatz JW; Tan BH
Ann N Y Acad Sci; 1994 May; 719():97-107. PubMed ID: 8010628
[TBL] [Abstract][Full Text] [Related]
16. Negative Selection Allows DNA Mismatch Repair-Deficient Mouse Fibroblasts
Zhang L; Lee M; Hao X; Ehlert J; Chi Z; Jin B; Maslov AY; Barabási AL; Hoeijmakers JHJ; Edelmann W; Vijg J; Dong X
bioRxiv; 2024 May; ():. PubMed ID: 38766154
[TBL] [Abstract][Full Text] [Related]
17. Linked-read analysis identifies mutations in single-cell DNA-sequencing data.
Bohrson CL; Barton AR; Lodato MA; Rodin RE; Luquette LJ; Viswanadham VV; Gulhan DC; Cortés-Ciriano I; Sherman MA; Kwon M; Coulter ME; Galor A; Walsh CA; Park PJ
Nat Genet; 2019 Apr; 51(4):749-754. PubMed ID: 30886424
[TBL] [Abstract][Full Text] [Related]
18. Genome aging: somatic mutation in the brain links age-related decline with disease and nominates pathogenic mechanisms.
Lodato MA; Walsh CA
Hum Mol Genet; 2019 Oct; 28(R2):R197-R206. PubMed ID: 31578549
[TBL] [Abstract][Full Text] [Related]
19. Base excision repair: a critical player in many games.
Wallace SS
DNA Repair (Amst); 2014 Jul; 19():14-26. PubMed ID: 24780558
[TBL] [Abstract][Full Text] [Related]
20. Replication-independent instability of Friedreich's ataxia GAA repeats during chronological aging.
Neil AJ; Hisey JA; Quasem I; McGinty RJ; Hitczenko M; Khristich AN; Mirkin SM
Proc Natl Acad Sci U S A; 2021 Feb; 118(5):. PubMed ID: 33495349
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]