BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

172 related articles for article (PubMed ID: 36059938)

  • 1. Shikonin ameliorated mice colitis by inhibiting dimerization and tetramerization of PKM2 in macrophages.
    Huang B; Wang Q; Jiang L; Lu S; Li C; Xu C; Wang C; Zhang E; Zhang X
    Front Pharmacol; 2022; 13():926945. PubMed ID: 36059938
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Shikonin Inhibits Tumor Growth in Mice by Suppressing Pyruvate Kinase M2-mediated Aerobic Glycolysis.
    Zhao X; Zhu Y; Hu J; Jiang L; Li L; Jia S; Zen K
    Sci Rep; 2018 Sep; 8(1):14517. PubMed ID: 30266938
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Shikonin Inhibits Tumor Growth of ESCC by suppressing PKM2 mediated Aerobic Glycolysis and STAT3 Phosphorylation.
    Zhang Q; Liu Q; Zheng S; Liu T; Yang L; Han X; Lu X
    J Cancer; 2021; 12(16):4830-4840. PubMed ID: 34234853
    [No Abstract]   [Full Text] [Related]  

  • 4. SIRT5 Desuccinylates and Activates Pyruvate Kinase M2 to Block Macrophage IL-1β Production and to Prevent DSS-Induced Colitis in Mice.
    Wang F; Wang K; Xu W; Zhao S; Ye D; Wang Y; Xu Y; Zhou L; Chu Y; Zhang C; Qin X; Yang P; Yu H
    Cell Rep; 2017 Jun; 19(11):2331-2344. PubMed ID: 28614718
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Shikonin induces hepatocellular carcinoma cell apoptosis by suppressing PKM2/PHD3/HIF-1
    Zhang H; Chen Z; Zhao X; Huo Q; Cheng X
    Nan Fang Yi Ke Da Xue Xue Bao; 2023 Jan; 43(1):92-98. PubMed ID: 36856215
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.
    Zhang H; Wang D; Li M; Plecitá-Hlavatá L; D'Alessandro A; Tauber J; Riddle S; Kumar S; Flockton A; McKeon BA; Frid MG; Reisz JA; Caruso P; El Kasmi KC; Ježek P; Morrell NW; Hu CJ; Stenmark KR
    Circulation; 2017 Dec; 136(25):2468-2485. PubMed ID: 28972001
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activator-Mediated Pyruvate Kinase M2 Activation Contributes to Endotoxin Tolerance by Promoting Mitochondrial Biogenesis.
    Yi Z; Wu Y; Zhang W; Wang T; Gong J; Cheng Y; Miao C
    Front Immunol; 2020; 11():595316. PubMed ID: 33542713
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Experimental Study of Hepatocellular Carcinoma Treatment by Shikonin Through Regulating PKM2.
    Liu T; Li S; Wu L; Yu Q; Li J; Feng J; Zhang J; Chen J; Zhou Y; Ji J; Chen K; Mao Y; Wang F; Dai W; Fan X; Wu J; Guo C
    J Hepatocell Carcinoma; 2020; 7():19-31. PubMed ID: 32110554
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PKM2 inhibitor shikonin suppresses TPA-induced mitochondrial malfunction and proliferation of skin epidermal JB6 cells.
    Li W; Liu J; Zhao Y
    Mol Carcinog; 2014 May; 53(5):403-12. PubMed ID: 23255458
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Shikonin inhibited glycolysis and sensitized cisplatin treatment in non-small cell lung cancer cells via the exosomal pyruvate kinase M2 pathway.
    Dai Y; Liu Y; Li J; Jin M; Yang H; Huang G
    Bioengineered; 2022 May; 13(5):13906-13918. PubMed ID: 35706397
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pyruvate Kinase M2 Tetramerization Protects against Hepatic Stellate Cell Activation and Liver Fibrosis.
    Zheng D; Jiang Y; Qu C; Yuan H; Hu K; He L; Chen P; Li J; Tu M; Lin L; Chen H; Lin Z; Lin W; Fan J; Cheng G; Hong J
    Am J Pathol; 2020 Nov; 190(11):2267-2281. PubMed ID: 32805235
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of pyruvate kinase M2 in oxidized LDL-induced macrophage foam cell formation and inflammation.
    Kumar A; Gupta P; Rana M; Chandra T; Dikshit M; Barthwal MK
    J Lipid Res; 2020 Mar; 61(3):351-364. PubMed ID: 31988148
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Shikonin inhibits immune checkpoint PD-L1 expression on macrophage in sepsis by modulating PKM2.
    Yuan L; Wang Y; Chen Y; Chen X; Li S; Liu X
    Int Immunopharmacol; 2023 Aug; 121():110401. PubMed ID: 37302371
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line.
    Yang W; Liu J; Hou L; Chen Q; Liu Y
    Life Sci; 2021 Jan; 265():118796. PubMed ID: 33220292
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sulforaphane diminishes moonlighting of pyruvate kinase M2 and interleukin 1β expression in M1 (LPS) macrophages.
    Bahiraii S; Brenner M; Yan F; Weckwerth W; Heiss EH
    Front Immunol; 2022; 13():935692. PubMed ID: 35983049
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Norisoboldine Attenuates Sepsis-Induced Acute Lung Injury by Modulating Macrophage Polarization via PKM2/HIF-1α/PGC-1α Pathway.
    Chen Q; Shao X; He Y; Lu E; Zhu L; Tang W
    Biol Pharm Bull; 2021; 44(10):1536-1547. PubMed ID: 34602563
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cynaroside prevents macrophage polarization into pro-inflammatory phenotype and alleviates cecal ligation and puncture-induced liver injury by targeting PKM2/HIF-1α axis.
    Pei L; Le Y; Chen H; Feng J; Liu Z; Zhu J; Wang C; Chen L; Dou X; Lu D
    Fitoterapia; 2021 Jul; 152():104922. PubMed ID: 33984439
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gene Regulatory Effect of Pyruvate Kinase M2 is Involved in Renal Inflammation in Type 2 Diabetic Nephropathy.
    Li L; Tang L; Yang X; Chen R; Zhang Z; Leng Y; Chen AF
    Exp Clin Endocrinol Diabetes; 2020 Sep; 128(9):599-606. PubMed ID: 31958846
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SENP3 facilitates M1 macrophage polarization via the HIF-1α/PKM2 axis in lipopolysaccharide-induced acute lung injury.
    He S; Fan C; Ji Y; Su Q; Zhao F; Xie C; Chen X; Zhang Y; Chen Y
    Innate Immun; 2023 Jan; 29(1-2):25-34. PubMed ID: 37016838
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lycium barbarum Polysaccharide Antagonizes LPS-Induced Inflammation by Altering the Glycolysis and Differentiation of Macrophages by Triggering the Degradation of PKM2.
    Ding H; Wang JJ; Zhang XY; Yin L; Feng T
    Biol Pharm Bull; 2021 Mar; 44(3):379-388. PubMed ID: 33390389
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.