138 related articles for article (PubMed ID: 36062554)
1. Anticancer Approach Inspired by the Hepatotoxic Mechanism of Pyrrolizidine Alkaloids with Glycosylated Artificial Metalloenzymes.
Kurimoto M; Chang TC; Nishiyama Y; Suzuki T; Dohmae N; Tanaka K; Yokoshima S
Angew Chem Int Ed Engl; 2022 Oct; 61(43):e202205541. PubMed ID: 36062554
[TBL] [Abstract][Full Text] [Related]
2. Pyrrole-protein adducts - A biomarker of pyrrolizidine alkaloid-induced hepatotoxicity.
Ma J; Xia Q; Fu PP; Lin G
J Food Drug Anal; 2018 Jul; 26(3):965-972. PubMed ID: 29976414
[TBL] [Abstract][Full Text] [Related]
3. Primary and secondary pyrrolic metabolites of pyrrolizidine alkaloids form DNA adducts in human A549 cells.
He X; Xia Q; Wu Q; Tolleson WH; Lin G; Fu PP
Toxicol In Vitro; 2019 Feb; 54():286-294. PubMed ID: 30366057
[TBL] [Abstract][Full Text] [Related]
4. Pulmonary toxicity is a common phenomenon of toxic pyrrolizidine alkaloids.
Song Z; He Y; Ma J; Fu PP; Lin G
J Environ Sci Health C Toxicol Carcinog; 2020; 38(2):124-140. PubMed ID: 32500835
[TBL] [Abstract][Full Text] [Related]
5. Intestinal and hepatic biotransformation of pyrrolizidine alkaloid N-oxides to toxic pyrrolizidine alkaloids.
Yang M; Ma J; Ruan J; Ye Y; Fu PP; Lin G
Arch Toxicol; 2019 Aug; 93(8):2197-2209. PubMed ID: 31222523
[TBL] [Abstract][Full Text] [Related]
6. Cytotoxicity of pyrrolizidine alkaloid in human hepatic parenchymal and sinusoidal endothelial cells: Firm evidence for the reactive metabolites mediated pyrrolizidine alkaloid-induced hepatotoxicity.
Yang M; Ruan J; Fu PP; Lin G
Chem Biol Interact; 2016 Jan; 243():119-26. PubMed ID: 26365561
[TBL] [Abstract][Full Text] [Related]
7. Effects of glutathione and cysteine on pyrrolizidine alkaloid-induced hepatotoxicity and DNA adduct formation in rat primary hepatocytes.
He X; Xia Q; Shi Q; Fu PP
J Environ Sci Health C Toxicol Carcinog; 2020; 38(2):109-123. PubMed ID: 32500832
[TBL] [Abstract][Full Text] [Related]
8. 7-Glutathione-pyrrole and 7-cysteine-pyrrole are potential carcinogenic metabolites of pyrrolizidine alkaloids.
He X; Xia Q; Fu PP
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2017 Apr; 35(2):69-83. PubMed ID: 28418776
[TBL] [Abstract][Full Text] [Related]
9. The role of formation of pyrrole-ATP synthase subunit beta adduct in pyrrolizidine alkaloid-induced hepatotoxicity.
Lu Y; Ma J; Song Z; Ye Y; Fu PP; Lin G
Arch Toxicol; 2018 Nov; 92(11):3403-3414. PubMed ID: 30244272
[TBL] [Abstract][Full Text] [Related]
10. Metabolic activation of pyrrolizidine alkaloids: insights into the structural and enzymatic basis.
Ruan J; Yang M; Fu P; Ye Y; Lin G
Chem Res Toxicol; 2014 Jun; 27(6):1030-9. PubMed ID: 24836403
[TBL] [Abstract][Full Text] [Related]
11. Correlation Investigation between Pyrrole-DNA and Pyrrole-Protein Adducts in Male ICR Mice Exposed to Retrorsine, a Hepatotoxic Pyrrolizidine Alkaloid.
Zhu L; Xue J; He Y; Xia Q; Fu PP; Lin G
Toxins (Basel); 2022 May; 14(6):. PubMed ID: 35737038
[TBL] [Abstract][Full Text] [Related]
12. Immunoassay approach for diagnosis of exposure to pyrrolizidine alkaloids.
Li N; Zhang F; Lian W; Wang H; Zheng J; Lin G
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2017 Jul; 35(3):127-139. PubMed ID: 28506107
[TBL] [Abstract][Full Text] [Related]
13. First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans.
Yang M; Ruan J; Gao H; Li N; Ma J; Xue J; Ye Y; Fu PP; Wang J; Lin G
Arch Toxicol; 2017 Dec; 91(12):3913-3925. PubMed ID: 28620673
[TBL] [Abstract][Full Text] [Related]
14. Developing urinary pyrrole-amino acid adducts as non-invasive biomarkers for identifying pyrrolizidine alkaloids-induced liver injury in human.
Zhu L; Zhang C; Zhang W; Xia Q; Ma J; He X; He Y; Fu PP; Jia W; Zhuge Y; Lin G
Arch Toxicol; 2021 Oct; 95(10):3191-3204. PubMed ID: 34390356
[TBL] [Abstract][Full Text] [Related]
15. Establishment of a novel CYP3A4-transduced human hepatic sinusoidal endothelial cell model and its application in screening hepatotoxicity of pyrrolizidine alkaloids.
Lu Y; Wong KY; Tan C; Ma J; Feng B; Lin G
J Environ Sci Health C Toxicol Carcinog; 2020; 38(2):169-185. PubMed ID: 32469285
[TBL] [Abstract][Full Text] [Related]
16. Protein cross-linking in primary cultured mouse hepatocytes by dehydropyrrolizidine alkaloids: Structure-toxicity relationship.
Xiong F; Jiang K; Chen Y; Ju Z; Yang L; Xiong A; Wang Z
Toxicon; 2020 Oct; 186():4-11. PubMed ID: 32687888
[TBL] [Abstract][Full Text] [Related]
17. 7-N-Acetylcysteine-pyrrole conjugate-A potent DNA reactive metabolite of pyrrolizidine alkaloids.
He X; Ma L; Xia Q; Fu PP
J Food Drug Anal; 2016 Oct; 24(4):682-694. PubMed ID: 28911605
[TBL] [Abstract][Full Text] [Related]
18. Editor's Highlight: Identification of Any Structure-Specific Hepatotoxic Potential of Different Pyrrolizidine Alkaloids Using Random Forests and Artificial Neural Networks.
Schöning V; Hammann F; Peinl M; Drewe J
Toxicol Sci; 2017 Dec; 160(2):361-370. PubMed ID: 28973379
[TBL] [Abstract][Full Text] [Related]
19. Metabolism-mediated cytotoxicity and genotoxicity of pyrrolizidine alkaloids.
He Y; Zhu L; Ma J; Lin G
Arch Toxicol; 2021 Jun; 95(6):1917-1942. PubMed ID: 34003343
[TBL] [Abstract][Full Text] [Related]
20. Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cells.
Abdelfatah S; Naß J; Knorz C; Klauck SM; Küpper JH; Efferth T
Cell Biol Toxicol; 2022 Apr; 38(2):325-345. PubMed ID: 33884520
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]