These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 36069327)

  • 1. Synthesis of obtusifoliol and analogues as CYP51 substrates.
    Churchman LR; Salisbury LJ; De Voss JJ
    Org Biomol Chem; 2022 Sep; 20(36):7316-7324. PubMed ID: 36069327
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Optimized expression and catalytic properties of a wheat obtusifoliol 14alpha-demethylase (CYP51) expressed in yeast. Complementation of erg11Delta yeast mutants by plant CYP51.
    Cabello-Hurtado F; Taton M; Forthoffer N; Kahn R; Bak S; Rahier A; Werck-Reichhart D
    Eur J Biochem; 1999 Jun; 262(2):435-46. PubMed ID: 10336628
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sterol content analysis suggests altered eburicol 14alpha-demethylase (CYP51) activity in isolates of Mycosphaerella graminicola adapted to azole fungicides.
    Bean TP; Cools HJ; Lucas JA; Hawkins ND; Ward JL; Shaw MW; Fraaije BA
    FEMS Microbiol Lett; 2009 Jun; 296(2):266-73. PubMed ID: 19459949
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular diversity of sterol 14alpha-demethylase substrates in plants, fungi and humans.
    Lamb DC; Kelly DE; Kelly SL
    FEBS Lett; 1998 Mar; 425(2):263-5. PubMed ID: 9559662
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cytochrome P450 lanosterol 14α-demethylase (CYP51): insights from molecular genetic analysis of the ERG11 gene in Saccharomyces cerevisiae.
    Loper JC
    J Steroid Biochem Mol Biol; 1992 Dec; 43(8):1107-16. PubMed ID: 22217856
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of the sterol 14α-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function.
    Fan J; Urban M; Parker JE; Brewer HC; Kelly SL; Hammond-Kosack KE; Fraaije BA; Liu X; Cools HJ
    New Phytol; 2013 May; 198(3):821-835. PubMed ID: 23442154
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CYP51 from Trypanosoma brucei is obtusifoliol-specific.
    Lepesheva GI; Nes WD; Zhou W; Hill GC; Waterman MR
    Biochemistry; 2004 Aug; 43(33):10789-99. PubMed ID: 15311940
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lipid signaling in plants. Cloning and expression analysis of the obtusifoliol 14alpha-demethylase from Solanum chacoense Bitt., a pollination- and fertilization-induced gene with both obtusifoliol and lanosterol demethylase activity.
    O'Brien M; Chantha SC; Rahier A; Matton DP
    Plant Physiol; 2005 Oct; 139(2):734-49. PubMed ID: 16169959
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Azole Antifungal Sensitivity of Sterol 14α-Demethylase (CYP51) and CYP5218 from Malassezia globosa.
    Warrilow AG; Price CL; Parker JE; Rolley NJ; Smyrniotis CJ; Hughes DD; Thoss V; Nes WD; Kelly DE; Holman TR; Kelly SL
    Sci Rep; 2016 Jun; 6():27690. PubMed ID: 27291783
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structure of cytochrome P450 14alpha -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors.
    Podust LM; Poulos TL; Waterman MR
    Proc Natl Acad Sci U S A; 2001 Mar; 98(6):3068-73. PubMed ID: 11248033
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification, modeling and ligand affinity of early deuterostome CYP51s, and functional characterization of recombinant zebrafish sterol 14α-demethylase.
    Morrison AM; Goldstone JV; Lamb DC; Kubota A; Lemaire B; Stegeman JJ
    Biochim Biophys Acta; 2014 Jun; 1840(6):1825-36. PubMed ID: 24361620
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Isolation and reconstitution of the heme-thiolate protein obtusifoliol 14alpha-demethylase from Sorghum bicolor (L.) Moench.
    Kahn RA; Bak S; Olsen CE; Svendsen I; Moller BL
    J Biol Chem; 1996 Dec; 271(51):32944-50. PubMed ID: 8955137
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural modeling of cytochrome P450 51 from a deep-sea fish points to a novel structural feature in other CYP51s.
    Goldstone JV; Lamb DC; Kelly SL; Lepesheva GI; Stegeman JJ
    J Inorg Biochem; 2023 Aug; 245():112241. PubMed ID: 37209461
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Clotrimazole as a potent agent for treating the oomycete fish pathogen Saprolegnia parasitica through inhibition of sterol 14α-demethylase (CYP51).
    Warrilow AG; Hull CM; Rolley NJ; Parker JE; Nes WD; Smith SN; Kelly DE; Kelly SL
    Appl Environ Microbiol; 2014 Oct; 80(19):6154-66. PubMed ID: 25085484
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Heterologous Expression of Full-Length Lanosterol 14α-Demethylases of Prominent Fungal Pathogens Candida albicans and Candida glabrata Provides Tools for Antifungal Discovery.
    Keniya MV; Ruma YN; Tyndall JDA; Monk BC
    Antimicrob Agents Chemother; 2018 Nov; 62(11):. PubMed ID: 30126959
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural analyses of
    Hargrove TY; Friggeri L; Wawrzak Z; Qi A; Hoekstra WJ; Schotzinger RJ; York JD; Guengerich FP; Lepesheva GI
    J Biol Chem; 2017 Apr; 292(16):6728-6743. PubMed ID: 28258218
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Recent advances in antifungal drug development targeting lanosterol 14α-demethylase (CYP51): A comprehensive review with structural and molecular insights.
    Singh A; Singh K; Sharma A; Kaur K; Chadha R; Bedi PMS
    Chem Biol Drug Des; 2023 Sep; 102(3):606-639. PubMed ID: 37220949
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural complex of sterol 14α-demethylase (CYP51) with 14α-methylenecyclopropyl-Delta7-24, 25-dihydrolanosterol.
    Hargrove TY; Wawrzak Z; Liu J; Waterman MR; Nes WD; Lepesheva GI
    J Lipid Res; 2012 Feb; 53(2):311-20. PubMed ID: 22135275
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular modelling of lanosterol 14 alpha-demethylase (CYP51) from Saccharomyces cerevisiae via homology with CYP102, a unique bacterial cytochrome P450 isoform: quantitative structure-activity relationships (QSARs) within two related series of antifungal azole derivatives.
    Lewis DF; Wiseman A; Tarbit MH
    J Enzyme Inhib; 1999; 14(3):175-92. PubMed ID: 10445042
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cloning and expression in Escherichia coli of the obtusifoliol 14 alpha-demethylase of Sorghum bicolor (L.) Moench, a cytochrome P450 orthologous to the sterol 14 alpha-demethylases (CYP51) from fungi and mammals.
    Bak S; Kahn RA; Olsen CE; Halkier BA
    Plant J; 1997 Feb; 11(2):191-201. PubMed ID: 9076987
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.