BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 36077308)

  • 41. Hypoxia increases the heterogeneity of melanoma cell populations and affects the response to vemurafenib.
    Pucciarelli D; Lengger N; Takáčová M; Csaderova L; Bartosova M; Breiteneder H; Pastorekova S; Hafner C
    Mol Med Rep; 2016 Apr; 13(4):3281-8. PubMed ID: 26936534
    [TBL] [Abstract][Full Text] [Related]  

  • 42. A Novel Plant Sesquiterpene Lactone Derivative, DETD-35, Suppresses BRAFV600E Mutant Melanoma Growth and Overcomes Acquired Vemurafenib Resistance in Mice.
    Feng JH; Nakagawa-Goto K; Lee KH; Shyur LF
    Mol Cancer Ther; 2016 Jun; 15(6):1163-76. PubMed ID: 27048951
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Long-term vemurafenib treatment drives inhibitor resistance through a spontaneous KRAS G12D mutation in a BRAF V600E papillary thyroid carcinoma model.
    Danysh BP; Rieger EY; Sinha DK; Evers CV; Cote GJ; Cabanillas ME; Hofmann MC
    Oncotarget; 2016 May; 7(21):30907-23. PubMed ID: 27127178
    [TBL] [Abstract][Full Text] [Related]  

  • 44. miR-7 reverses the resistance to BRAFi in melanoma by targeting EGFR/IGF-1R/CRAF and inhibiting the MAPK and PI3K/AKT signaling pathways.
    Sun X; Li J; Sun Y; Zhang Y; Dong L; Shen C; Yang L; Yang M; Li Y; Shen G; Tu Y; Tao J
    Oncotarget; 2016 Aug; 7(33):53558-53570. PubMed ID: 27448964
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Everolimus selectively targets vemurafenib resistant BRAF
    Ruzzolini J; Peppicelli S; Andreucci E; Bianchini F; Margheri F; Laurenzana A; Fibbi G; Pimpinelli N; Calorini L
    Cancer Lett; 2017 Nov; 408():43-54. PubMed ID: 28826720
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Acquisition of resistance to vemurafenib leads to interleukin-10 production through an aberrant activation of Akt in a melanoma cell line.
    Inozume T; Tsunoda T; Morisaki T; Harada K; Shirasawa S; Kawamura T
    J Dermatol; 2018 Dec; 45(12):1434-1439. PubMed ID: 30222203
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Novel ATP-competitive MEK inhibitor E6201 is effective against vemurafenib-resistant melanoma harboring the MEK1-C121S mutation in a preclinical model.
    Narita Y; Okamoto K; Kawada MI; Takase K; Minoshima Y; Kodama K; Iwata M; Miyamoto N; Sawada K
    Mol Cancer Ther; 2014 Apr; 13(4):823-32. PubMed ID: 24448821
    [TBL] [Abstract][Full Text] [Related]  

  • 48. The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma.
    Van Allen EM; Wagle N; Sucker A; Treacy DJ; Johannessen CM; Goetz EM; Place CS; Taylor-Weiner A; Whittaker S; Kryukov GV; Hodis E; Rosenberg M; McKenna A; Cibulskis K; Farlow D; Zimmer L; Hillen U; Gutzmer R; Goldinger SM; Ugurel S; Gogas HJ; Egberts F; Berking C; Trefzer U; Loquai C; Weide B; Hassel JC; Gabriel SB; Carter SL; Getz G; Garraway LA; Schadendorf D;
    Cancer Discov; 2014 Jan; 4(1):94-109. PubMed ID: 24265153
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Detailed imaging and genetic analysis reveal a secondary BRAF(L505H) resistance mutation and extensive intrapatient heterogeneity in metastatic BRAF mutant melanoma patients treated with vemurafenib.
    Hoogstraat M; Gadellaa-van Hooijdonk CG; Ubink I; Besselink NJ; Pieterse M; Veldhuis W; van Stralen M; Meijer EF; Willems SM; Hadders MA; Kuilman T; Krijgsman O; Peeper DS; Koudijs MJ; Cuppen E; Voest EE; Lolkema MP
    Pigment Cell Melanoma Res; 2015 May; 28(3):318-23. PubMed ID: 25515853
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Hypoxia-Driven Mechanism of Vemurafenib Resistance in Melanoma.
    Qin Y; Roszik J; Chattopadhyay C; Hashimoto Y; Liu C; Cooper ZA; Wargo JA; Hwu P; Ekmekcioglu S; Grimm EA
    Mol Cancer Ther; 2016 Oct; 15(10):2442-2454. PubMed ID: 27458138
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Dissecting Mechanisms of Melanoma Resistance to BRAF and MEK Inhibitors Revealed Genetic and Non-Genetic Patient- and Drug-Specific Alterations and Remarkable Phenotypic Plasticity.
    Hartman ML; Sztiller-Sikorska M; Gajos-Michniewicz A; Czyz M
    Cells; 2020 Jan; 9(1):. PubMed ID: 31936151
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Joint action of miR-126 and MAPK/PI3K inhibitors against metastatic melanoma.
    Pedini F; De Luca G; Felicetti F; Puglisi R; Boe A; Arasi MB; Fratini F; Mattia G; Spada M; Caporali S; Biffoni M; Giuliani A; Carè A; Felli N
    Mol Oncol; 2019 Sep; 13(9):1836-1854. PubMed ID: 31115969
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Aurora B is regulated by the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway and is a valuable potential target in melanoma cells.
    Bonet C; Giuliano S; Ohanna M; Bille K; Allegra M; Lacour JP; Bahadoran P; Rocchi S; Ballotti R; Bertolotto C
    J Biol Chem; 2012 Aug; 287(35):29887-98. PubMed ID: 22767597
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance.
    Shi H; Moriceau G; Kong X; Lee MK; Lee H; Koya RC; Ng C; Chodon T; Scolyer RA; Dahlman KB; Sosman JA; Kefford RF; Long GV; Nelson SF; Ribas A; Lo RS
    Nat Commun; 2012 Mar; 3():724. PubMed ID: 22395615
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Mitochondrial complex I inhibitor deguelin induces metabolic reprogramming and sensitizes vemurafenib-resistant BRAF
    Carpenter EL; Chagani S; Nelson D; Cassidy PB; Laws M; Ganguli-Indra G; Indra AK
    Mol Carcinog; 2019 Sep; 58(9):1680-1690. PubMed ID: 31211467
    [TBL] [Abstract][Full Text] [Related]  

  • 56. CHMFL-BMX-078, a BMX inhibitor, overcomes the resistance of melanoma to vemurafenib via inhibiting AKT pathway.
    Jiang S; Jiang T; Huang H; Chen X; Li L; Wang Z; Fei J; Liu C; Liu Z; Cheng Y
    Chem Biol Interact; 2022 Jan; 351():109747. PubMed ID: 34813779
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Evolving Acquired Vemurafenib Resistance in a BRAF V600E Mutant Melanoma PDTX Model to Reveal New Potential Targets.
    Tóvári J; Vári-Mező D; Surguta SE; Ladányi A; Kigyós A; Cserepes M
    Cells; 2023 Jul; 12(14):. PubMed ID: 37508582
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Reversing vemurafenib-resistance in primary melanoma cells by combined romidepsin and type I IFN treatment through blocking of tumorigenic signals and induction of immunogenic effects.
    Fragale A; Stellacci E; Romagnoli G; Licursi V; Parlato S; Canini I; Remedi G; Buoncervello M; Matarrese P; Pedace L; Ascione B; Pizzi S; Tartaglia M; D'Atri S; Presutti C; Capone I; Gabriele L
    Int J Cancer; 2023 Sep; 153(5):1080-1095. PubMed ID: 37293858
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells.
    Faião-Flores F; Alves-Fernandes DK; Pennacchi PC; Sandri S; Vicente AL; Scapulatempo-Neto C; Vazquez VL; Reis RM; Chauhan J; Goding CR; Smalley KS; Maria-Engler SS
    Oncogene; 2017 Mar; 36(13):1849-1861. PubMed ID: 27748762
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Evaluating melanoma drug response and therapeutic escape with quantitative proteomics.
    Rebecca VW; Wood E; Fedorenko IV; Paraiso KH; Haarberg HE; Chen Y; Xiang Y; Sarnaik A; Gibney GT; Sondak VK; Koomen JM; Smalley KS
    Mol Cell Proteomics; 2014 Jul; 13(7):1844-54. PubMed ID: 24760959
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.