BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 36077614)

  • 1. DNA Polymerase Theta Plays a Critical Role in Pancreatic Cancer Development and Metastasis.
    Smolinska A; Singer K; Golchert J; Smyczynska U; Fendler W; Sendler M; van den Brandt J; Singer S; Homuth G; Lerch MM; Moskwa P
    Cancers (Basel); 2022 Aug; 14(17):. PubMed ID: 36077614
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Loss of ATRX Increases Susceptibility to Pancreatic Injury and Oncogenic KRAS in Female But Not Male Mice.
    Young CC; Baker RM; Howlett CJ; Hryciw T; Herman JE; Higgs D; Gibbons R; Crawford H; Brown A; Pin CL
    Cell Mol Gastroenterol Hepatol; 2019; 7(1):93-113. PubMed ID: 30510993
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ANGPTL4 accelerates KRAS
    Yan HH; Jung KH; Lee JE; Son MK; Fang Z; Park JH; Kim SJ; Kim JY; Lim JH; Hong SS
    Cancer Lett; 2021 Oct; 519():185-198. PubMed ID: 34311032
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The biological features of PanIN initiated from oncogenic Kras mutation in genetically engineered mouse models.
    Shen R; Wang Q; Cheng S; Liu T; Jiang H; Zhu J; Wu Y; Wang L
    Cancer Lett; 2013 Oct; 339(1):135-43. PubMed ID: 23887057
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16.
    Chalabi-Dchar M; Cassant-Sourdy S; Duluc C; Fanjul M; Lulka H; Samain R; Roche C; Breibach F; Delisle MB; Poupot M; Dufresne M; Shimaoka T; Yonehara S; Mathonnet M; Pyronnet S; Bousquet C
    Gastroenterology; 2015 Jun; 148(7):1452-65. PubMed ID: 25683115
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A genetically engineered mouse model developing rapid progressive pancreatic ductal adenocarcinoma.
    Yamaguchi T; Ikehara S; Nakanishi H; Ikehara Y
    J Pathol; 2014 Oct; 234(2):228-38. PubMed ID: 25042889
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.
    Bardeesy N; Cheng KH; Berger JH; Chu GC; Pahler J; Olson P; Hezel AF; Horner J; Lauwers GY; Hanahan D; DePinho RA
    Genes Dev; 2006 Nov; 20(22):3130-46. PubMed ID: 17114584
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA Polymerase θ: A Unique Multifunctional End-Joining Machine.
    Black SJ; Kashkina E; Kent T; Pomerantz RT
    Genes (Basel); 2016 Sep; 7(9):. PubMed ID: 27657134
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma.
    Zhang W; Nandakumar N; Shi Y; Manzano M; Smith A; Graham G; Gupta S; Vietsch EE; Laughlin SZ; Wadhwa M; Chetram M; Joshi M; Wang F; Kallakury B; Toretsky J; Wellstein A; Yi C
    Sci Signal; 2014 May; 7(324):ra42. PubMed ID: 24803537
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis.
    Nishikawa Y; Kodama Y; Shiokawa M; Matsumori T; Marui S; Kuriyama K; Kuwada T; Sogabe Y; Kakiuchi N; Tomono T; Mima A; Morita T; Ueda T; Tsuda M; Yamauchi Y; Sakuma Y; Ota Y; Maruno T; Uza N; Uesugi M; Kageyama R; Chiba T; Seno H
    Oncogene; 2019 May; 38(22):4283-4296. PubMed ID: 30705405
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MicroRNA-21 is induced early in pancreatic ductal adenocarcinoma precursor lesions.
    du Rieu MC; Torrisani J; Selves J; Al Saati T; Souque A; Dufresne M; Tsongalis GJ; Suriawinata AA; Carrère N; Buscail L; Cordelier P
    Clin Chem; 2010 Apr; 56(4):603-12. PubMed ID: 20093556
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer.
    Morton JP; Timpson P; Karim SA; Ridgway RA; Athineos D; Doyle B; Jamieson NB; Oien KA; Lowy AM; Brunton VG; Frame MC; Evans TR; Sansom OJ
    Proc Natl Acad Sci U S A; 2010 Jan; 107(1):246-51. PubMed ID: 20018721
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nucleoside Analogs Radiosensitize G0 Cells by Activating DNA End Resection and Alternative End-Joining.
    Magin S; Meher PK; Iliakis G
    Radiat Res; 2021 May; 195(5):412-426. PubMed ID: 33755161
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues.
    Aichler M; Seiler C; Tost M; Siveke J; Mazur PK; Da Silva-Buttkus P; Bartsch DK; Langer P; Chiblak S; Dürr A; Höfler H; Klöppel G; Müller-Decker K; Brielmeier M; Esposito I
    J Pathol; 2012 Apr; 226(5):723-34. PubMed ID: 21984419
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oncogenic ERBB2 aberrations and KRAS mutations cooperate to promote pancreatic ductal adenocarcinoma progression.
    Li Z; Shao C; Liu X; Lu X; Jia X; Zheng X; Wang S; Zhu L; Li K; Pang Y; Xie F; Lu Y; Wang Y
    Carcinogenesis; 2020 Mar; 41(1):44-55. PubMed ID: 31046123
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alternative end-joining repair pathways are the ultimate backup for abrogated classical non-homologous end-joining and homologous recombination repair: Implications for the formation of chromosome translocations.
    Iliakis G; Murmann T; Soni A
    Mutat Res Genet Toxicol Environ Mutagen; 2015 Nov; 793():166-75. PubMed ID: 26520387
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inactivation of APC Induces CD34 Upregulation to Promote Epithelial-Mesenchymal Transition and Cancer Stem Cell Traits in Pancreatic Cancer.
    Hsieh MJ; Chiu TJ; Lin YC; Weng CC; Weng YT; Hsiao CC; Cheng KH
    Int J Mol Sci; 2020 Jun; 21(12):. PubMed ID: 32586050
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inactivation of Smad4 accelerates Kras(G12D)-mediated pancreatic neoplasia.
    Kojima K; Vickers SM; Adsay NV; Jhala NC; Kim HG; Schoeb TR; Grizzle WE; Klug CA
    Cancer Res; 2007 Sep; 67(17):8121-30. PubMed ID: 17804724
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Marked contribution of alternative end-joining to chromosome-translocation-formation by stochastically induced DNA double-strand-breaks in G2-phase human cells.
    Soni A; Siemann M; Pantelias GE; Iliakis G
    Mutat Res Genet Toxicol Environ Mutagen; 2015 Nov; 793():2-8. PubMed ID: 26520366
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Zeb1 in Stromal Myofibroblasts Promotes
    Sangrador I; Molero X; Campbell F; Franch-Expósito S; Rovira-Rigau M; Samper E; Domínguez-Fraile M; Fillat C; Castells A; Vaquero EC
    Cancer Res; 2018 May; 78(10):2624-2637. PubMed ID: 29490942
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.