BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 36083801)

  • 21. G protein-coupled receptor kinase 2 promotes high-level Hedgehog signaling by regulating the active state of Smo through kinase-dependent and kinase-independent mechanisms in Drosophila.
    Chen Y; Li S; Tong C; Zhao Y; Wang B; Liu Y; Jia J; Jiang J
    Genes Dev; 2010 Sep; 24(18):2054-67. PubMed ID: 20844016
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Hedgehog reciprocally controls trafficking of Smo and Ptc through the Smurf family of E3 ubiquitin ligases.
    Li S; Li S; Wang B; Jiang J
    Sci Signal; 2018 Feb; 11(516):. PubMed ID: 29438012
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Smoothened oligomerization/higher order clustering in lipid rafts is essential for high Hedgehog activity transduction.
    Shi D; Lv X; Zhang Z; Yang X; Zhou Z; Zhang L; Zhao Y
    J Biol Chem; 2013 May; 288(18):12605-14. PubMed ID: 23532857
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The last 59 amino acids of Smoothened cytoplasmic tail directly bind the protein kinase Fused and negatively regulate the Hedgehog pathway.
    Malpel S; Claret S; Sanial M; Brigui A; Piolot T; Daviet L; Martin-Lannerée S; Plessis A
    Dev Biol; 2007 Mar; 303(1):121-33. PubMed ID: 17182028
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Phosphorylation of the atypical kinesin Costal2 by the kinase Fused induces the partial disassembly of the Smoothened-Fused-Costal2-Cubitus interruptus complex in Hedgehog signalling.
    Ruel L; Gallet A; Raisin S; Truchi A; Staccini-Lavenant L; Cervantes A; Thérond PP
    Development; 2007 Oct; 134(20):3677-89. PubMed ID: 17881487
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Hedgehog induces formation of PKA-Smoothened complexes to promote Smoothened phosphorylation and pathway activation.
    Li S; Ma G; Wang B; Jiang J
    Sci Signal; 2014 Jul; 7(332):ra62. PubMed ID: 24985345
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The extracellular loops of Smoothened play a regulatory role in control of Hedgehog pathway activation.
    Carroll CE; Marada S; Stewart DP; Ouyang JX; Ogden SK
    Development; 2012 Feb; 139(3):612-21. PubMed ID: 22223683
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Drosophila miR-5 suppresses Hedgehog signaling by directly targeting Smoothened.
    Wu LF; Gao L; Hou XM; Zhang QH; Li S; Yang YF; Lin XH
    FEBS Lett; 2012 Nov; 586(22):4052-60. PubMed ID: 23085394
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Hedgehog-regulated ubiquitination controls smoothened trafficking and cell surface expression in Drosophila.
    Li S; Chen Y; Shi Q; Yue T; Wang B; Jiang J
    PLoS Biol; 2012 Jan; 10(1):e1001239. PubMed ID: 22253574
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Hedgehog regulates smoothened activity by inducing a conformational switch.
    Zhao Y; Tong C; Jiang J
    Nature; 2007 Nov; 450(7167):252-8. PubMed ID: 17960137
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Distinct phosphorylations on kinesin costal-2 mediate differential hedgehog signaling strength.
    Ranieri N; Ruel L; Gallet A; Raisin S; Thérond PP
    Dev Cell; 2012 Feb; 22(2):279-94. PubMed ID: 22306085
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Hedgehog activates fused through phosphorylation to elicit a full spectrum of pathway responses.
    Zhou Q; Kalderon D
    Dev Cell; 2011 Jun; 20(6):802-14. PubMed ID: 21664578
    [TBL] [Abstract][Full Text] [Related]  

  • 33. An intracellular activation of Smoothened that is independent of Hedgehog stimulation in
    Jiang K; Liu Y; Zhang J; Jia J
    J Cell Sci; 2018 Jan; 131(1):. PubMed ID: 29142103
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Hh-induced Smoothened conformational switch is mediated by differential phosphorylation at its C-terminal tail in a dose- and position-dependent manner.
    Fan J; Liu Y; Jia J
    Dev Biol; 2012 Jun; 366(2):172-84. PubMed ID: 22537496
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Protein association changes in the Hedgehog signaling complex mediate differential signaling strength.
    Giordano C; Ruel L; Poux C; Therond P
    Development; 2018 Dec; 145(24):. PubMed ID: 30541874
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Hrs promotes ubiquitination and mediates endosomal trafficking of smoothened in Drosophila hedgehog signaling.
    Fan J; Jiang K; Liu Y; Jia J
    PLoS One; 2013; 8(11):e79021. PubMed ID: 24244405
    [TBL] [Abstract][Full Text] [Related]  

  • 37. SUMO regulates the activity of Smoothened and Costal-2 in Drosophila Hedgehog signaling.
    Zhang J; Liu Y; Jiang K; Jia J
    Sci Rep; 2017 Feb; 7():42749. PubMed ID: 28195188
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Transducing the Hedgehog signal across the plasma membrane.
    Zhao Y; Tong C; Jiang J
    Fly (Austin); 2007; 1(6):333-6. PubMed ID: 18820483
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Transduction of the Hedgehog signal through the dimerization of Fused and the nuclear translocation of Cubitus interruptus.
    Zhang Y; Mao F; Lu Y; Wu W; Zhang L; Zhao Y
    Cell Res; 2011 Oct; 21(10):1436-51. PubMed ID: 21844892
    [TBL] [Abstract][Full Text] [Related]  

  • 40. E3 ligase Herc4 regulates Hedgehog signalling through promoting Smoothened degradation.
    Jiang W; Yao X; Shan Z; Li W; Gao Y; Zhang Q
    J Mol Cell Biol; 2019 Sep; 11(9):791-803. PubMed ID: 30925584
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.