BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 36089748)

  • 1. Design and Characterization of a Natural Arf-GEFs Inhibitor Prodrug
    Jiang YY; Gao Y; Liu JY; Xu Y; Wei MY; Wang CY; Gu YC; Shao CL
    J Med Chem; 2022 Sep; 65(18):11970-11984. PubMed ID: 36089748
    [TBL] [Abstract][Full Text] [Related]  

  • 2. New brefeldin A-cinnamic acid ester derivatives as potential antitumor agents: Design, synthesis and biological evaluation.
    Jiang YY; Wu S; Wu YW; Gao Y; Chong D; Sun C; Wei MY; Gu YC; Shao CL; Gu Y
    Eur J Med Chem; 2022 Oct; 240():114598. PubMed ID: 35849940
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Preparation and evaluation of sulfide derivatives of the antibiotic brefeldin a as potential prodrug candidates with enhanced aqueous solubilities.
    Fox BM; Vroman JA; Fanwick PE; Cushman M
    J Med Chem; 2001 Nov; 44(23):3915-24. PubMed ID: 11689077
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dual specificity of the interfacial inhibitor brefeldin a for arf proteins and sec7 domains.
    Zeeh JC; Zeghouf M; Grauffel C; Guibert B; Martin E; Dejaegere A; Cherfils J
    J Biol Chem; 2006 Apr; 281(17):11805-14. PubMed ID: 16484231
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Si113-prodrugs selectively activated by plasmin against hepatocellular and ovarian carcinoma.
    Rango E; D'Antona L; Iovenitti G; Brai A; Mancini A; Zamperini C; Trivisani CI; Marianelli S; Fallacara AL; Molinari A; Cianciusi A; Schenone S; Perrotti N; Dreassi E; Botta M
    Eur J Med Chem; 2021 Nov; 223():113653. PubMed ID: 34161866
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BEN3/BIG2 ARF GEF is Involved in Brefeldin A-Sensitive Trafficking at the trans-Golgi Network/Early Endosome in Arabidopsis thaliana.
    Kitakura S; Adamowski M; Matsuura Y; Santuari L; Kouno H; Arima K; Hardtke CS; Friml J; Kakimoto T; Tanaka H
    Plant Cell Physiol; 2017 Oct; 58(10):1801-1811. PubMed ID: 29016942
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evaluation of a reductively activated duocarmycin prodrug against murine and human solid cancers.
    Vielhauer GA; Swink M; Parelkar NK; Lajiness JP; Wolfe AL; Boger D
    Cancer Biol Ther; 2013 Jun; 14(6):527-36. PubMed ID: 23760495
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and evaluation of nitroheterocyclic carbamate prodrugs for use with nitroreductase-mediated gene-directed enzyme prodrug therapy.
    Hay MP; Anderson RF; Ferry DM; Wilson WR; Denny WA
    J Med Chem; 2003 Dec; 46(25):5533-45. PubMed ID: 14640560
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and Characterization of a Pyridone-Containing EZH2 Inhibitor Phosphate Prodrug.
    Kung PP; Fan C; Gukasyan HJ; Huang B; Kephart S; Kraus M; Lee JH; Sutton SC; Yamazaki S; Zehnder L
    J Med Chem; 2021 Feb; 64(3):1725-1732. PubMed ID: 33529029
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development of water-soluble prodrugs of the HIV-1 protease inhibitor KNI-727: importance of the conversion time for higher gastrointestinal absorption of prodrugs based on spontaneous chemical cleavage.
    Sohma Y; Hayashi Y; Ito T; Matsumoto H; Kimura T; Kiso Y
    J Med Chem; 2003 Sep; 46(19):4124-35. PubMed ID: 12954064
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dibrefeldins A and B, A pair of epimers representing the first brefeldin A dimers with cytotoxic activities from Penicillium janthinellum.
    Zeng F; Chen C; Al Chnani AA; Zhou Q; Tong Q; Wang W; Zang Y; Gong J; Wu Z; Liu J; Wang J; Zhu H; Zhang Y
    Bioorg Chem; 2019 May; 86():176-182. PubMed ID: 30711700
    [TBL] [Abstract][Full Text] [Related]  

  • 12. GBF1, a guanine nucleotide exchange factor for Arf, is crucial for coxsackievirus B3 RNA replication.
    Lanke KH; van der Schaar HM; Belov GA; Feng Q; Duijsings D; Jackson CL; Ehrenfeld E; van Kuppeveld FJ
    J Virol; 2009 Nov; 83(22):11940-9. PubMed ID: 19740986
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Highly water-soluble prodrugs of anthelmintic benzimidazole carbamates: synthesis, pharmacodynamics, and pharmacokinetics.
    Chassaing C; Berger M; Heckeroth A; Ilg T; Jaeger M; Kern C; Schmid K; Uphoff M
    J Med Chem; 2008 Mar; 51(5):1111-4. PubMed ID: 18271517
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, chemical and enzymatic hydrolysis, and bioavailability evaluation in rabbits of metronidazole amino acid ester prodrugs with enhanced water solubility.
    Mahfouz NM; Hassan MA
    J Pharm Pharmacol; 2001 Jun; 53(6):841-8. PubMed ID: 11428660
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and in vitro/in vivo evaluation of novel oral N-alkyl- and N,N-dialkyl-carbamate esters of entacapone.
    Savolainen J; Leppanen J; Forsberg M; Taipale H; Nevalainen T; Huuskonen J; Gynther J; Mannisto PT; Jarvinen T
    Life Sci; 2000; 67(2):205-16. PubMed ID: 10901288
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of butanoate, retinoate, and bis(2,2,2-trichloroethyl)phosphate derivatives of 5-fluoro-2'-deoxyuridine and 2',5-difluoro-2'-deoxyuridine as potential dual action anticancer prodrugs.
    Xia Z; Wiebe LI; Miller GG; Knaus EE
    Arch Pharm (Weinheim); 1999 Aug; 332(8):286-94. PubMed ID: 10489539
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design and synthesis of brefeldin A sulfide derivatives as prodrug candidates with enhanced aqueous solubilities.
    Argade AB; Devraj R; Vroman JA; Haugwitz RD; Hollingshead M; Cushman M
    J Med Chem; 1998 Aug; 41(18):3337-46. PubMed ID: 9719586
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Purification and cloning of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors.
    Togawa A; Morinaga N; Ogasawara M; Moss J; Vaughan M
    J Biol Chem; 1999 Apr; 274(18):12308-15. PubMed ID: 10212200
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nonselective Chemical Inhibition of Sec7 Domain-Containing ARF GTPase Exchange Factors.
    Mishev K; Lu Q; Denoo B; Peurois F; Dejonghe W; Hullaert J; De Rycke R; Boeren S; Bretou M; De Munck S; Sharma I; Goodman K; Kalinowska K; Storme V; Nguyen LSL; Drozdzecki A; Martins S; Nerinckx W; Audenaert D; Vert G; Madder A; Otegui MS; Isono E; Savvides SN; Annaert W; De Vries S; Cherfils J; Winne J; Russinova E
    Plant Cell; 2018 Oct; 30(10):2573-2593. PubMed ID: 30018157
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and Synthesis of Polymer Prodrugs for Improving Water-Solubility, Pharmacokinetic Behavior and Antitumor Efficacy of TXA9.
    Li Y; Ye C; Cai C; Zhao M; Han N; Liu Z; Zhai J; Yin J
    Pharm Res; 2020 Mar; 37(3):66. PubMed ID: 32166420
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.